Gonadtropin-releasing hormone agonist combined with addback therapy in the treatment of endometriosis

Objectives:To explore the clinical efficacy of taking gonadotrophin-releasing hormone agonist combined with addback therapy for patients with endometriosis after laparoscopic surgery.Method:116 patients were selected who received laparoscopic surgical treatment,and they were randomly divided into observation group and control group.In both groups,the patients were operated with laparoscopic surgery.The patients in the control group were given postoperative light gonadorelin treatment while the patients in the observation group received reverse adding treatment.And the indicators of sex hormone level and the pain degree score were recorded and compared in the two groups.Results:In the observation group,the sex hormone level improved,and the pain score improvement was superior to that of the control group,with statistically significant difference(P0.05).In the observation group,the patients' relapse rate was lower than that in the control group,with statistically significant difference(P0.05).Conclusion:For Endometriosis cyst patients,using gonadotrophin-releasing hormone agonist joint add-on therapy after laparoscopic surgery is safe and effective,which can reduce the recurrence rate and the patients pain symptom scores,with less effect on endocrine metabolism.