Targeted Lung Health Check: breast related incidental findings-imaging appearances and lessons learned.
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This study analyzed incidental breast findings during lung cancer screening, identifying breast nodules as the most common finding, with smooth, well-defined nodules being benign and recommending established referral pathways.
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Abstract
ObjectiveThe introduction of Targeted Lung Health Checks (TLHC) to screen for lung cancer has highlighted that incidental findings are common and require management strategies. This study analyses retrospectively, incidentally detected breast lesions reported as part of the TLHC referred to the Breast Cancer clinicians.MethodsAll participants with incidental breast nodules referred to the Breast Cancer team in the first year of screening were reviewed.ResultsFifty-two participants (48 female; 92.3%) were referred to the Breast Multidisciplinary Team Meeting for assessment of 43 breast nodules, 8 breast asymmetry/dense breasts, and 2 likely breast related metastatic disease. One participant declined breast team referral. For the 42 breast nodules investigated, the final diagnoses were 5 breast carcinomas, 10 normal breast tissue, and 27 benign nodules. One male patient was diagnosed with breast carcinoma. The 29 breast nodules classified as smooth and well defined were all benign. No malignancy was demonstrated in the group with asymmetric or dense breast tissue. Metastatic breast carcinoma was confirmed in two participants. Twenty-six out of thirty-seven (54%) females had prior breast screening mammograms precluding further investigation.ConclusionIncidental breast nodules are common on THLC scans. Smooth, sharply defined breast nodules are likely to be benign but low-dose CT is poor at accurately assessing breast nodules. Agreed breast referral pathways prior to starting the Lung Cancer Screening programme are recommended. Access to screening mammograms can reduce referrals to the Breast clinic.Advances in knowledgeLessons learned from TLHC pilot studies can be useful to sites commencing national TLHC programme.
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- europepmc
- last seen: 2026-08-01T06:07:04.264727+00:00