Diagnostic value of CA125 in serum and peritoneal fluid for endometriosis and adenomyosis

Objective:To investigate the diagnostic value of CA125 in serum and peritoneal fluid(PF) for endometriosis(EM) and adenomyosis.Methods:CA125 in serum and PF were measured using the chemiluminescent enzyme immunometric assay in 40 EM,23 adenomyosis and 15 of control group.Results:Both the serum CA125 level of EM and adenomyosis were significant higher than that of control group(P0.01).The positive rate of serum CA125 of adenomyosis was significant higher than that of EM(P0.01).There was significant difference in the measurement of CA125 of PF between EM and control group(P0.01),but showed no significant diffenence between adenomyosis and control group.There were no significant difference in the serum CA125 between mild EM and control group,but show significant difference in PF CA125.Of the severe EM patients,both the CA125 of serum and PF were significant higher than that of the control(P0.01).Conclusion:PF CA125 is more sensitive than serum CA125 in diagnosis of EM,and less sensitive in diagnosis of adenomyosis.