Novel anionic magnetic nanosorbent for the automatic and simultaneous determination of arsenic and antimony by MSPE-HG-ICP-MS

Novel anionic magnetic nanosorbent for the automatic and simultaneous determination of arsenic and antimony by MSPE-HG-ICP-MS | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Novel anionic magnetic nanosorbent for the automatic and simultaneous determination of arsenic and antimony by MSPE-HG-ICP-MS Irene Morales-Benítez, Álvaro Doblado-Onieva, Irene Sánchez-Trujillo, and 3 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-9190679/v1 This work is licensed under a CC BY 4.0 License Status: Under Review Version 1 posted 8 You are reading this latest preprint version Abstract Antimony and arsenic are two pollutants known for their bioaccumulative effects and toxic properties even in low concentrations, therefore there is a need to develop efficient and reliable extraction and preconcentration methods of these analytes in water systems simultaneously. In this work, an online ultratrace extraction and preconcentration methodology for environmental waters was carried out by combining magnetic solid phase extraction (MSPE), hydride generation (HG) and inductively coupled plasma mass spectrometry (ICP-MS). A novel anionic nanosorbent, called M@GONIO, based on graphene oxide and magnetic nanoparticles functionalized with ammonium groups was designed, synthesized, and characterized for MSPE. The developed method was carefully optimized through univariate analysis and response surface methodology based on a central composite design. Under the optimized conditions, the enrichment factors for As and Sb were 84.7 and 84.6, respectively. The intra-day and inter-day precision expressed as relative standard deviation (RSD) were below 5.1% in all the evaluated conditions. The proposed analytical method was successfully validated and applied to the determination of trace of As and Sb in environmental waters from diverse origin. Full Text Additional Declarations No competing interests reported. Supplementary Files GraphicalAbstract.png Cite Share Download PDF Status: Under Review Version 1 posted Editorial decision: Revision requested 02 May, 2026 Reviews received at journal 19 Apr, 2026 Reviewers agreed at journal 05 Apr, 2026 Reviewers agreed at journal 31 Mar, 2026 Reviewers invited by journal 31 Mar, 2026 Editor assigned by journal 26 Mar, 2026 Submission checks completed at journal 26 Mar, 2026 First submitted to journal 22 Mar, 2026 You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. 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Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-9190679","acceptedTermsAndConditions":true,"allowDirectSubmit":false,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":615271677,"identity":"531e165e-6df3-4c39-8533-73aa33d121ca","order_by":0,"name":"Irene Morales-Benítez","email":"","orcid":"","institution":"University of Malaga","correspondingAuthor":false,"prefix":"","firstName":"Irene","middleName":"","lastName":"Morales-Benítez","suffix":""},{"id":615271678,"identity":"6ab382a3-805f-49d4-81ae-ba6e8a42a644","order_by":1,"name":"Álvaro Doblado-Onieva","email":"","orcid":"","institution":"University of Malaga","correspondingAuthor":false,"prefix":"","firstName":"Álvaro","middleName":"","lastName":"Doblado-Onieva","suffix":""},{"id":615271679,"identity":"7660b24d-a84e-472a-90ff-4a503f04d68b","order_by":2,"name":"Irene Sánchez-Trujillo","email":"","orcid":"","institution":"University of Malaga","correspondingAuthor":false,"prefix":"","firstName":"Irene","middleName":"","lastName":"Sánchez-Trujillo","suffix":""},{"id":615271680,"identity":"b3626fb6-e386-46a1-bb7b-d44828282e41","order_by":3,"name":"Carlos Vereda-Alonso","email":"","orcid":"","institution":"University of Malaga","correspondingAuthor":false,"prefix":"","firstName":"Carlos","middleName":"","lastName":"Vereda-Alonso","suffix":""},{"id":615271681,"identity":"a051ac66-d9bf-4682-975d-b1e8a71a0b37","order_by":4,"name":"Mª del Mar López Guerrero","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAApElEQVRIiWNgGAWjYFAC5gYQKUeKFkawFmPStSQ2EK1Bd9rBxscFFXXpG64dfsDw4Q8RWsxuJzYbzzjDlrvhdpoB48w24rS0SfO28QC1JBgw8xLjPIiWfxLpBrfTPzD/IdJhQC0NBgkGt3MMmBnYiNMC9MuxBMOZt3MKDvYS55fkg48Laurk+W6nb3zwgxiHgQAzjHGASA1IWkbBKBgFo2AUYAUACZ443fWhRHsAAAAASUVORK5CYII=","orcid":"","institution":"University of Malaga","correspondingAuthor":true,"prefix":"","firstName":"Mª","middleName":"del Mar López","lastName":"Guerrero","suffix":""},{"id":615271682,"identity":"99718d3e-34ec-4c66-a1a7-6ccaa5976d0c","order_by":5,"name":"Elisa I. 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