The application of laparoscopic operation and drugs in diagnosing and treating endometriosis midrange and severe

In: Journal of laparoscopic surgery · 2008 · W2379356212
article OA: closed CC0 ⤵ 1 in-corpus citation
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This study compared mifepristone and gestrione post-laparoscopic surgery for midrange and severe endometriosis, finding gestrione had a higher effect rate and lower relapse rate.

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Abstract

Objective:To explore the effect of diagnosing and treating midrange and severe endometriosis with laparoscope and drugs.Methods:The 98 cases of endometriosis diagnosed with laparoscope from December 2003 to December 2006 were divided into two groups A and B.Group A was treated with mifepristone while group B with gestrione postoperatively.The rate of effect,relapse and pregnancy operatively,level of CA125,function of liver and kidney were compared during the following up of 12 to 36 months.Results:The effect rate of group A and B is 60.0% and 84.3%.The relapse rate of group B is lower than group A.There are significant difference between the two groups(P0.05).Conclusions:Mifepristone and gestrione are both effective in treating midrange and severe endometriosis after laparoscopic operation.Mifepristone is better than gestrione with no influence on endometrium and effect on relapse endometriosis.

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endometriosis

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