Whole-genome methylation profiling of menstrual stem cells identifies novel biomarkers for endometriosis

Raúl Pérez-Moraga, Cemsel Bafligil
2025 · doi:10.5281/zenodo.15878286 · W7151751707
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Whole-genome methylation profiling of menstrual blood-derived mesenchymal stem cells was performed to identify novel biomarkers associated with endometriosis.

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This data paper describes the bioinformatics scripts and methodologies employed for whole-genome methylation profiling of DNA extracted from menstrual blood-derived mesenchymal stem cells. The primary objective of this computational analysis was to identify distinct epigenetic patterns that could serve as novel biomarkers for endometriosis. By detailing the analytical pipeline, the authors provide a reproducible framework for investigating the role of MenSCs in the pathophysiology of the disease. This paper is centrally about endometriosis — specifically focusing on the identification of diagnostic biomarkers through methylation analysis of menstrual stem cells.

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Abstract

This repository contains scripts used in the bioinformatics analysis of DNA methylation in menstrual blood-derived mesenchymal stem cells (MenSCs), aiming to identify biomarkers related to endometriosis.
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Published July 14, 2025 | Version v1 Data paper Open Whole-genome methylation profiling of menstrual stem cells identifies novel biomarkers for endometriosis Contributors Contact person: - 1. endogene.bio - 2. Complejo Hosiptalario Universitario Insular Materno Infantil de Canarias, Las Palmas de Gran Canaria, Spain - 3. Department of Gynecology, Institut Clínic of Gynecology, Obstetrics and Neonatology, Hospital Clínic of Barcelona, Institut d'Investigacions Biomédiques August Pi I Sunyer (IDIBAPS), Barcelona Spain - 4. Service of Gynecology, Institut Clínic of Gynecology, Obstetrics and Neonatology, Hospital Clínic of Barcelona, Universitat de Barcelona, Institut d'Investigacions Biomédiques August Pi I Sunyer (IDIBAPS), Barcelona Spain Description This repository contains scripts used in the bioinformatics analysis of DNA methylation in menstrual blood-derived mesenchymal stem cells (MenSCs), aiming to identify biomarkers related to endometriosis.

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endometriosis

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last seen: 2026-06-10T17:14:06.276822+00:00
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