Markers of connective tissue dysplasia in patients with chronic venouse insufficiency

Elena I. Rusina
In: Journal of obstetrics and women's diseases · 2005 · vol. 54(5S) , pp. 100–101 · doi:10.17816/jowd87604 · W3212082400
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-08 ⓘ

This study investigated markers of connective tissue dysplasia in patients experiencing chronic venous insufficiency.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-10 · read from full text ⓘ

This review article evaluates markers of connective tissue dysplasia in 25 female patients with chronic pelvic pain and pelvic varicose, using laparoscopic findings and a physical examination assessing 65 connective-tissue dysplasia indicators. All participants had unilateral or bilateral varicose parametrial veins; nine patients (36%) showed thinness or defects of the uterine wide ligaments, while no other reproductive system diseases were found. The study reports that 96% had at least one dysplasia marker (most commonly migraine, asthenic somatotype, easy hemorrhage, and vegetative dysfunction), and that 85% also had dysembriogenesis stigmata. Relevance to endometriosis: the paper’s introduction states that pelvic varicose is associated with different gynecologic diseases including endometriosis, though the study itself focused on connective tissue dysplasia markers in patients with pelvic varicose.

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Abstract

Introduction. Pelvic varicose is associated with different gynecologic diseases (myoma, ovarian tumors, endometriosis and others). Also it may be the independent disorder and cause chronic pelvic pain, sterility. The role of connective tissue disoders in varicose progressing is studed actively.
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Abstract

Introduction. Pelvic varicose is associated with different gynecologic diseases (myoma, ovarian tumors, endometriosis and others). Also it may be the independent disorder and cause chronic pelvic pain, sterility. The role of connective tissue disoders in varicose progressing is studed actively. Full Text Introduction. Pelvic varicose is associated with different gynecologic diseases (myoma, ovarian tumors, endometriosis and others). Also it may be the independent disorder and cause chronic pelvic pain, sterility. The role of connective tissue disoders in varicose progressing is studed actively.

Objective

to evaluate markers of connective tissue displasia in female patients with pelvic varicose.

Materials and methods

The laporoscopy and physical exam were performed in 25 female patients (mean age range 32 ± 5,5 years) with symptoms of chronic pelvic pain. Physical examination was done to asses sixty five markers of connective tissue displasia by author's algorithm.

Results

Unilateral or bilateral varicose parametrial veins were found in all patients during laporoscopy. Nine patients (36%) had thinness or defects of uterine wide ligaments. Another diseases of reproductive system were not found. Twenty four patients (96%) had any markers of connective tissue displasia, such as migraine (91%), asthenic somatotype (74%), easy haemorrage formation (65%), vegetative disfunction (63%), constipation (55%), joint hypermobility (49%), thorax and spine deformation (36%), vaginal prolaps I - II (25%). Combination of 6-10 markers were found in 78% cases, 10-15 markers - in 22% cases. Any disembriogenesis stigms such as - the distorted little finger, epicantus, teeth anomaly, deformation of external ear, sandal shaped foot were found in 85% patients.

Conclusion

Markers of connective tissue system disorder were revealed in the most of patients with pelvic varicose. It is necessary take into account for risk groups formation and choice of treatment methods for patients with this disease. About the authors E. I. Rusina Ott’s Research Institute of Obstetrics and Gynecology RAMS Author for correspondence. Email: [email protected] Doctor of Medical Sciences Russian Federation, Saint-Petersburg

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endometriosischronic_pelvic_pain

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