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This letter discusses the exclusion criteria for subjects in a study investigating reactive oxygen species (ROS) and its link to pregnancy outcomes, suggesting a larger sample size for studies on ROS in endometriosis.
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Abstract
women who had salpingectomy for ectopic pregnancy and prox-imal tubal obstruction because of low-grade infection or fimbrial occlusion with or without mild peritubal adhesion). Tubal infer-tility associated with gross hydrosalpingeal changes, dense pel-vic adhesion because of endometriosis or pelvic inflammatory disease (PID) was excluded. In other words, our subjects had no chronic disease condition. This was done to account for the fact that diseased conditions are often associated with reactive oxy-gen species (ROS) generation. Presently, we are not in a position to comment on the high levels of ROS in endometriosis as mentioned by Attaran et al. (2000). It is, however, suggested that the sample size be increased for assessing ROS levels in endometriosis as only 12 subjects are reported by the group which appear to be too small a population to comment on the significant correlation between ROS and pregnancy outcome in endometriosis.
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- openalex
- last seen: 2026-05-11T09:01:08.081461+00:00
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