To block estrogen's synthesis or action: that is the question

Richard J. Santen, Santen RJ
The Journal of clinical endocrinology and metabolism · 2002 · doi:10.1210/jcem.87.7.8589 · PMID:12107191
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-08-08 ⓘ

This paper explores the contrasting strategies of blocking estrogen synthesis versus blocking its action, a fundamental decision in developing anti-estrogen therapies.

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Condition tags

endometriosis

MeSH descriptors

Aromatase Inhibitors Breast Neoplasms Endometrial Neoplasms Endometriosis Enzyme Inhibitors Estrogen Antagonists Infertility, Female Breast Neoplasms Endometrial Neoplasms Endometriosis Enzyme Inhibitors Estrogen Antagonists Female Humans Infertility, Female

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europepmc
last seen: 2026-09-20T09:27:46.357103+00:00
pubmed
last seen: 2026-05-13T22:13:07.520820+00:00
unpaywall
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License: public-domain-us · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine