Surgical Outcomes and Complications of Laparoscopic Hysterectomy for Endometriosis: A Multicentric Cohort Study

Jvan Casarin, Casarin J, Fabio Ghezzi, Ghezzi F, Mueller M, Michael D. Mueller, Michael Mueller, Marcello Ceccaroni, Ceccaroni M, Andrea Papadia, Papadia A, Helder Ferreira, Hélder Ferreira, Uccella S, Stefano Uccella, Malzoni M, Mario Malzoni, Mabrouk M, Mohamed Mabrouk, Seracchioli R, Renato Seracchioli, Bordi G, Giulia Bordi, Baldo Emanuele Gisone, Gisone BE, Baldo Gisone, Vaineau C, Cloé Vaineau, Giorgio Bogani, Giovanni Roviglione, Roviglione G, Arena A, Alessandro Arena, Andrea Luigi Ambrosoli, Carla Graf, Graf C, Bruni F, Francesco Bruni, Rafael Bras, Rafael Brás, Bras R, Falcone F, Francesca Falcone, Diego Raimondo, Giovanni AD, A. Di Giovanni, Alessandra Di Giovanni, Antonella Cromi, Cromi A
Journal of Minimally Invasive Gynecology · 2023 · vol. 30(7) , pp. 587–592 · doi:10.1016/j.jmig.2023.03.018 · PMID:37004810 · W4362472507
article OA: green CC0 ⤵ 4 in-corpus citations
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⚙ AI-generated summary by gemini-2.5-flash-lite+body, 2026-06-10 ⓘ

This multicentric cohort study evaluated surgical outcomes and complications associated with laparoscopic hysterectomy performed for endometriosis.

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I can’t access the actual paper content because the provided text is a server “anti-bot” page (Anubis proof-of-work) rather than study methods or results, so there’s no information to summarize. Without the study’s population, design, outcomes, or limitations as written, I can’t accurately paraphrase the paper’s findings. The paper cannot be summarized from the text provided, and this limits the ability to extract any scientific conclusions. This paper is centrally about endometriosis — it is titled as a multicentric cohort study of laparoscopic hysterectomy outcomes and complications for endometriosis.

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Abstract

STUDY OBJECTIVE: To investigate the postoperative morbidity of laparoscopic hysterectomy (LH) for endometriosis/adenomyosis in terms of operative outcomes and complications. DESIGN: Retrospective multicentric cohort study. SETTING: Eight European minimally invasive referral centers. PATIENTS: Data from 995 patients with pathologically confirmed endometriosis and/or adenomyosis who underwent LH without concomitant urological and/or gastroenterological procedures from January 2010 to December 2020. INTERVENTIONS: Total LH. MEASUREMENTS AND MAIN RESULTS: Demographic patients' characteristics, surgical outcomes, and intraoperative and postoperative complications were evaluated. We considered major postoperative surgical-related complications, any grade 2 or more events (Clavien-Dindo score) that occurred within 30 days from surgery. Univariate analysis and multivariable models fit with logistic regression were used to estimate the adjusted odds ratio (OR) and corresponding 95% confidence interval (CI) for major complications. Median age at surgery was 44 years (28-54), and about half of them (505, 50.7%) were on medical treatment (estro-progestins, progestin, or Gonadotropin hormone-releasing hormone-analogues) at the time of surgery. In association with LH, posterior adhesiolysis was performed in 387 (38.9%) cases and deep nodule resection in 302 (30.0%). Intraoperative complications occurred in 3% of the patients, and major postoperative complications were registered in 93 (9.3%). The multivariable analysis showed an inverse correlation between the occurrence of Clavien-Dindo >2 complications and age (OR 0.94, 95% CI 0.90-0.99), while previous surgery for endometriosis (OR 1.62, 95% CI 1.01-2.60) and intraoperative complications (OR 6.49, 95% CI 2.65-16.87) were found as predictors of major events. Medical treatment at the time of surgery has emerged as a protective factor (OR 0.50, 95% CI 0.31-0.81). CONCLUSION: LH for endometriosis/adenomyosis is associated with non-negligible morbidity. Knowing the factors associated with higher risks of complications might be used for risk stratification and could help clinicians during preoperative counseling. The administration of estro-progestin or progesterone preoperatively might reduce the risks of postoperative complications following surgery.
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Condition tags

endometriosis

MeSH descriptors

Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis Adenomyosis

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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