Expression of Sema 3A, Plexin A1 and NRP-1 in peritoneal endometriotic lesions and deep infiltrating endometriotic lesions of uterosacral ligament.

A: Comparison of semi-quantitative expression of Sema 3A, Plexin A1 and NRP-1 of glandular epithelial cells between peritoneal endometriosis, deep infiltrating endometriosis of uterosacral ligament and eutopic endometrium from patients with endometriosis (EM) as well as without endometriosis (NEM). B: Comparison of semi-quantitative expression of Sema 3A, Plexin A1 and NRP-1 of stromal cells between peritoneal endometriosis, deep infiltrating endometriosis of uterosacral ligament and eutopic endometrium from patients with endometriosis (EM) as well as without endometriosis (NEM). C: Immunohistochemical staining of Sema 3A, Plexin A1 and NRP-1 in PEM and USL-EM. PEM: peritoneal endometriosis; USL-EM: deep infiltrating endometriosis of uterosacral ligament. (immunohistochemical stain, 200 × magnification) Mann-Whitney test: *P<0.05 (versus NEM); ** P<0.001 (versus EM); §P<0.05 (versus NEM); §§P<0.001(versus EM); NS, not significant.