High Anti-Müllerian Hormone Strongly Correlates with Reproductive Outcomes in Women Undergoing Assisted Reproduction

Masoome Jabarpour; Jabarpour M; Amidi F; Fardin Amidi; Sahar Rostami; Rostami S; Aleyasin A; Ashraf Aleyasin; Marzieh Aghahosseini; Aghahosseini M; Khodarahmian M; Mahshad Khodarahmian; Aida Najafian; Najafian A; Hosseinimousa S; Sedigheh Hosseinimousa; Yasaman Abbasi; Abbasi Y; Maryam Shabani Nashtaei; Nashtaei MS

doi:10.7754/clin.lab.2023.230524

High Anti-Müllerian Hormone Strongly Correlates with Reproductive Outcomes in Women Undergoing Assisted Reproduction

Masoome Jabarpour, Jabarpour M, Amidi F, Fardin Amidi, Sahar Rostami, Rostami S, Aleyasin A, Ashraf Aleyasin, Marzieh Aghahosseini, Aghahosseini M, Khodarahmian M, Mahshad Khodarahmian, Aida Najafian, Najafian A, Hosseinimousa S, Sedigheh Hosseinimousa, Yasaman Abbasi, Abbasi Y, Maryam Shabani Nashtaei, Nashtaei MS

Clinical laboratory · 2023 · vol. 69(12/2023) · doi:10.7754/clin.lab.2023.230524 · PMID:38084695 · W4389616511

article OA: closed CC0

Full text JSON View on OpenAlex View on PubMed View at publisher

⚙ AI-generated summary by claude@2026-06, 2026-06-13 ⓘ

This study found that high anti-Müllerian hormone levels strongly correlate with improved outcomes in women undergoing assisted reproduction, regardless of age or infertility cause.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

⚙ AI-generated deep summary by claude@2026-06, 2026-06-13 · read from full text ⓘ

This retrospective cohort study evaluated 881 women aged 20–45 with gynecologic or unexplained infertility who underwent their first fresh autologous ART cycle (2012–2020) without preimplantation genetic diagnosis, examining how serum anti-Müllerian hormone (AMH) relates to reproductive outcomes across infertility causes that included endometriosis. The authors found that higher AMH was strongly associated with better outcomes independent of age and infertility cause, including more oocytes, more mature (MII) oocytes, more good-quality embryos, higher chemical and clinical pregnancy rates, and a higher live birth rate in the reported analyses. The paper’s major caveat is that AMH should not be used as the only predictive marker, and it calls for larger studies to define specific AMH cutoff values for accurate prediction. Relevance to endometriosis: the study included women with endometriosis among infertility causes and reports that the AMH–outcome correlations held independent of the cause of infertility, which encompasses endometriosis.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Abstract

BACKGROUND: In a retrospective cohort of 881 women with gynecologic and unexplained infertility, we aimed to study the relationship between serum AMH levels and ART outcomes. This retrospective cohort includes 881 infertile women aged 20 - 45 who underwent their first fresh autologous non-preimplantation genetic diagnosis ART cycles between 2012 and 2020. METHODS: We assessed the correlation between AMH levels and reproductive outcomes among infertile women with different causes of infertility (including endometriosis, polycystic ovary syndrome (PCOS), and unexplained infertility). RESULTS: We found a strong correlation between high AMH levels and reproductive outcomes independent of age and the cause of infertility in women undergoing ART. In all patients with gynecologic and unexplained infertility, higher AMH correlated with the improved number of oocytes (p < 0.001), MII oocytes (p < 0.001), good-quality embryos (p < 0.001), chemical pregnancy rate (p < 0.001 in women < 37; and p = 0.002 in women over 37), clinical pregnancy rate (p < 0.05), and live birth rate (p = 0.05). CONCLUSIONS: Serum AMH concentrations can be invaluable for predicting ovarian reserve and reproductive outcomes in young and advanced-age infertile patients undergoing ART. However, it should not be used as the sole predictive marker for disqualifying infertile women from ART treatment. Further large cohort studies are warranted to determine an exact cutoff point for AMH to provide an accurate ART success prediction.

Full text 1,876 characters · extracted from oa-doi-fallback · 5 sections · click to expand

Abstract

| High Anti-Müllerian Hormone Strongly Correlates with Reproductive Outcomes in Women Undergoing Assisted Reproduction by Masoome Jabarpour, Fardin Amidi, Sahar Rostami, Ashraf Aleyasin, Marzieh Aghahosseini, Mahshad Khodarahmian, Aida Najafian, Sedigheh Hosseinimousa, Yasaman Abbasi, Maryam Shabani Nashtaei | | |

Background

In a retrospective cohort of 881 women with gynecologic and unexplained infertility, we aimed to study the relationship between serum AMH levels and ART outcomes. This retrospective cohort includes 881 infertile women aged 20 - 45 who underwent their first fresh autologous non–preimplantation genetic diagnosis ART cycles between 2012 and 2020.

Methods

We assessed the correlation between AMH levels and reproductive outcomes among infertile women with different causes of infertility (including endometriosis, polycystic ovary syndrome (PCOS), and unexplained infertility).

Results

We found a strong correlation between high AMH levels and reproductive outcomes independent of age and the cause of infertility in women undergoing ART. In all patients with gynecologic and unexplained infertility, higher AMH correlated with the improved number of oocytes (p < 0.001), MII oocytes (p < 0.001), good-quality embryos (p < 0.001), chemical pregnancy rate (p < 0.001 in women < 37; and p = 0.002 in women over 37), clinical pregnancy rate (p < 0.05), and live birth rate (p = 0.05).

Conclusions

Serum AMH concentrations can be invaluable for predicting ovarian reserve and reproductive outcomes in young and advanced-age infertile patients undergoing ART. However, it should not be used as the sole predictive marker for disqualifying infertile women from ART treatment. Further large cohort studies are warranted to determine an exact cutoff point for AMH to provide an accurate ART success prediction. DOI: 10.7754/Clin.Lab.2023.230524 |

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

⚙ Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback ⓘ

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Condition tags

endometriosisinfertility

MeSH descriptors

Infertility, Female Infertility, Female Infertility, Female Infertility, Female Infertility, Female Infertility, Female Infertility, Female Infertility, Female Infertility, Female Infertility, Female Infertility, Female Infertility, Female Infertility, Female Infertility, Female Infertility, Female Infertility, Female Infertility, Female Infertility, Female Infertility, Female Infertility, Female

Citation neighborhood (no data yet)

We don't have any in-corpus citations linked to this paper yet. The paper's references may be in our DB but unresolved to ``paper_id`` (resolution happens at ingest when the cited DOI matches a row we already have). Run the cross-source citation reconcile pass to retry.

Source provenance

europepmc: last seen: 2026-07-27T06:15:28.040536+00:00
openalex: last seen: 2026-06-04T00:00:01.174412+00:00
pubmed: last seen: 2026-07-27T06:13:39.119345+00:00

License: CC0 · commercial use OK