Considerations in selecting appropriate medical therapy for endometriosis.

M Y Dawood, M. Yusoff Dawood
International Journal of Gynecology & Obstetrics · 1993 · vol. 40 Suppl , pp. S29–42 · PMID:8099023 · W2440312036
article OA: closed CC0 ⤵ 3 in-corpus citations
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This review examines the mechanisms and compares the efficacy, side effects, and fertility implications of hormonal therapies for endometriosis based on patient factors and disease stage.

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Abstract

The mechanisms of action of estrogen/progestin oral contraceptives, derivatives of testosterone including danazol and synthetic luteinizing hormone or gonadotropin-releasing hormone agonists in the treatment of endometriosis are reviewed. The selection of therapy depends on the stage of endometriosis, symptoms, current and future fertility needs, patient's age and recurrence rates. The efficacy, dosing regimens, effects on menstruation and fertility, recurrence rates and potential adverse effects, with particular emphasis on bone loss, of alternative therapies are compared.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Bone Density Bone Density Contraceptives, Oral, Hormonal Contraceptives, Oral, Hormonal Contraceptives, Oral, Hormonal Danazol Danazol Danazol Drug Administration Routes Drug Administration Schedule Endometriosis Female Fertility Fertility Gestrinone Gestrinone Gestrinone Gonadotropin-Releasing Hormone Gonadotropin-Releasing Hormone

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Cited by (3)

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License: CC0 · commercial use OK