Experience with the Tecnis Symfony Extended Range of Vision IOL in Patients with Pre- existing Retinal Pathology

Background: There are limited publications about multifocal IOLs and patients with pre-existing retinal pathologies. Published outcomes have been mixed, with some showing good visualization of the retina postoperatively, while others report difficulty with visualization of the retina through MIOL. This study evaluated outcomes with TECNIS Symfony ® Extended Range of Vision IOL (Symfony) in patients with and without pre-existing retinal pathology. Methods: Visual acuity (VA) was retrospectively evaluated for patients who underwent cataract surgery with implantation of the Symfony IOL from 09/1/2016 to 05/31/2018 at a single, US clinical site. Month 2 postoperative outcomes were compared for eyes with (70 eyes) and without pre-existing retinal pathology (616 eyes). Outcomes included mean monocular uncorrected visual acuity (±SD) at near (UNVA) at 40 cm, far distance (UDVA) at 20 ft, and with best correction (CDVA). Results: UNVA was 0.07 ± 0.10 logMAR in the non-pathology eyes vs. 0.17 ± 0.20 logMAR in eyes with pathology (p<0.0001). Mean monocular UDVA was 0.11 ± 0.90 logMAR in the non-pathology eyes vs. 0.21± 0.19 logMAR in eyes with pathology (p<0.0001). Mean monocular CDVA was 0.02 ± 0.06 logMAR in the non-pathology eyes vs. 0.11± 0.17 logMAR in eyes with pathology (p<0.0001). Eyes with mild to moderate pathology had VA comparable with non-pathology eyes. Conclusion: In this retrospective review, the Symfony IOL provided good uncorrected and best-corrected visual acuity at near and far distances in eyes with and without retinal pathology. Trial Registration: NCT05111106 (clinicaltrials.gov)