Implantable Collamer Lenses (ICL) for treating keratoconus

Abstract Purpose: Implantable Collamer Lens (ICL) implantation is a promising solution for correcting refractive errors, particularly in advanced Keratoconus (KC). Despite its increasing use, comprehensive data on its efficacy and complications remain limited, especially in regions with high KC prevalence like the Middle East.This study aims to evaluate ICL implantation's effectiveness in KC patients, examining demographic factors and various variables, while examining the alterations in various ocular parameters. Methodology: This retrospective longitudinal study included 38 eyes of 20 patients who underwent ICL implantation for KC at Al Shami Eye Center in Amman, Jordan between 2017 and 2020. The study compared preoperative and postoperative data, including demographic information, Endothelial Cell Density, Central Corneal Thickness, Anterior Chamber Depth, Anterior Chamber Angle, Anterior Chamber Volume, Spherical Power, Cylinder Power, Spherical Equivalent, Intraocular Pressure, and white-to-white. Results: Significant improvements were observed in refractive outcomes, with reductions in spherical equivalent and cylinder power (both p < 0.00001). Visual acuity also improved significantly (p < 0.00001), However, certain anterior chamber parameters and endothelial cell density showed concerning changes postoperatively. Conclusion: ICL implantation effectively improved visual and refractive outcomes for KC patients. Concerns were raised regarding changes in anterior chamber parameters and endothelial cell density, but stable intraocular pressure and central corneal thickness were found postoperatively.