Chronic Endometritis and Endometriosis: Two Sides of the Same Coin?

Kalaitzopoulos, Dimitrios Rafail, Catena, Ursula, Kohl Schwartz, Alexandra, Schoretsanitis, Georgios, Leeners, Brigitte, Drakopoulos, Panagiotis, Samartzis, Nicolas
2025 · doi:10.48620/84980 · W6892108039
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This meta-analysis found a 28% prevalence of chronic endometritis in women with endometriosis, significantly higher than in controls, and a higher rate in advanced endometriosis stages.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-07 · read from full text ⓘ

I can’t access the paper’s content because the provided text is a server protection/anti-scraping page (Anubis proof-of-work challenge) rather than the study itself, so the study design, population, results, and limitations aren’t available to summarize. The only information present is about why the website blocks automated access and that modern JavaScript is required. The paper’s title suggests a conceptual discussion relating chronic endometritis and endometriosis, but no actual findings or methods are accessible in what I received. This paper is centrally about endometriosis — it is framed as linking chronic endometritis with endometriosis.

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Abstract

Both chronic endometritis and endometriosis are common entities in infertile patients. The association and the co-existence of these two entities are poorly evaluated. The aim of this systematic review and meta-analysis was to examine the association between chronic endometritis and endometriosis and to find the prevalence of chronic endometritis in women with endometriosis. A systematic electronic search was conducted using the MEDLINE, Scopus and Cochrane databases up to May 2022. Observational studies which examined the prevalence of chronic endometritis in women with endometriosis were included. Newcastle-Ottawa Scale was used for the quality assessment. Odds ratios (OR) with 95% confidence intervals (CIs) for dichotomous outcomes and pooled prevalences with 95% CIs were calculated. 855 studies were identified, of which six studies were included in the systematic review and five in the meta-analysis. The prevalence of chronic endometritis in women with endometriosis was 28%, with higher frequency observed in women with endometriosis rASRM stage III-IV (43%) in comparison to women with endometriosis rASRM stage I-II (25%). The meta-analysis showed a significantly higher chronic endometritis in women with endometriosis in comparison to the control group (five studies, 264 endometriosis vs. 435 control, OR = 2.07; 95% CI 1.11-3.84, I2 43%, p = 0.02). The present meta-analysis showed a significantly higher risk of chronic endometritis in women with endometriosis in comparison to the control group. These findings contribute to a better understanding of the causes and consequences of endometriosis and chronic endometritis and may help in the development of more efficient treatment strategies for women with associated infertility.
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Outcome instruments

rASRM

Condition tags

endometriosisinfertility

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