Drugs for chronic pain in children: a commentary on clinical practice and the absence of evidence

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This commentary examines pharmacological approaches to pediatric chronic pain, highlighting the lack of evidence and identifying knowledge gaps to suggest future research directions for clinical care.

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Abstract

Pediatric chronic pain is widespread, under-recognized and undertreated. Best management usually involves a multimodal approach coordinated by a multidisciplinary team. The present commentary specifically discusses common pharmacological approaches to chronic pain in children, identifies gaps in knowledge and suggests several research directions that would benefit future clinical care.

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MeSH descriptors

Analgesics Chronic Pain Pain Management Adolescent Analgesics Child Chronic Pain Humans Pain Management

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europepmc
last seen: 2026-10-25T09:32:14.900964+00:00
pubmed
last seen: 2026-10-08T21:11:31.379484+00:00
License: CC-BY-4.0 · commercial use OK · attribution required
Per Europe PMC