An adverse event after high-intensity focused ultrasound treatment.

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This case report describes a 46-year-old woman with adenomyosis who developed transient rectal wall signal changes after high-intensity focused ultrasound treatment, which resolved with conservative management.

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This study evaluated the optimization of treatment parameters for high-intensity focused ultrasound in patients with uterine adenomyosis, reporting both short-term and long-term clinical outcomes. The authors illustrated a specific adverse event involving rectal wall inflammation that occurred immediately following the procedure but resolved with conservative management within one month. Despite this complication, the imaging results demonstrated successful shrinkage of the adenomyotic lesions and symptom improvement in the patient. This paper is centrally about adenomyosis — specifically focusing on the efficacy and safety profile of high-intensity focused ultrasound treatment for the condition.

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Abstract

Sagittal T2-weighted images (A, B, E) and contrast-enhanced T1-weighted images (C, D) of a 46-year-old woman with adenomyosis (arrowhead). (A) Before HIFU treatment. (B, C) Increased signal intensity and enhancement along the anterior wall of the upper rectum adjacent to the adenomyosis was detected in the immediate posttreatment images (arrows). Her symptoms improved after conservative management, and she was discharged. (D, E) At the 1-month follow-up, the signal intensity of the rectal wall was normalized (arrow). Note the shrinkage of the treated adenomyosis (arrowhead).
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Optimized treatment parameter by computer simulation for high-intensity focused ultrasound treatment of uterine adenomyosis: Short-term and long-term results Fig 4 An adverse event after high-intensity focused ultrasound treatment. Sagittal T2-weighted images (A, B, E) and contrast-enhanced T1-weighted images (C, D) of a 46-year-old woman with adenomyosis (arrowhead). (A) Before HIFU treatment. (B, C) Increased signal intensity and enhancement along the anterior wall of the upper rectum adjacent to the adenomyosis was detected in the immediate posttreatment images (arrows). Her symptoms improved after conservative management, and she was discharged. (D, E) At the 1-month follow-up, the signal intensity of the rectal wall was normalized (arrow). Note the shrinkage of the treated adenomyosis (arrowhead).

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adenomyosis

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last seen: 2026-05-11T08:54:20.463269+00:00
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