Influence of the operative treatment of leiomyomas on lipid profile.

Alfred Reroń; Hubert Huras

Influence of the operative treatment of leiomyomas on lipid profile.

Alfred Reroń, Hubert Huras

In: Neuro endocrinology letters · 2004 · vol. 25(6) , pp. 429–34 · PMID:15665805 · W2399486009

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This study analyzed 130 women with leiomyomas and found that cholesterol, HDL, and LDL levels decreased 10 days post-surgery but returned to baseline at 6 months, with hysterectomy and bilateral oophorectomy showing the highest lipid levels at 6 months.

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This 2004 study in Neuro-Endocrinology Letters examined how operative treatment of uterine leiomyomas affected patients’ lipid profiles, using clinical assessment of lipid-related measurements before and after surgery. The key reported outcome was that the operative management of leiomyomas was associated with changes in lipid profile parameters. A major limitation is that the provided paper text contains only bibliographic metadata and does not specify the sample size, exact lipid outcomes, follow-up duration, or statistical details needed to fully interpret the findings. The paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Abstract

OBJECTIVE: The aim of this study was to asses the influence of operative treatment of leiomyomas on lipid profile. The study was conducted from April 1, 2000, through April 30, 2002 in The Department of Septic Gynecology and Obstetrics at Collegium Medicum of the Jagiellonian University. METHODOLOGY: Most hysterectomies are performed because of leiomyomas, which are the most common benign tumors of the female reproductive organ. Pathogenesis and evolution of uterine leiomyomas are not well understood. Treatment of leiomyomas is divided into operative and inoperative. Operative methods include generally laparoscopic myomectomy, conservative myomectomy and hysterectomy. 130 women with diagnosed leiomyomas were analyzed in four groups. CONCLUSION: Regardless of the type of performed surgery, decrease in cholesterol, HDL and LDL are observed 10 days after operation, with return to preoperative values at 6 months after surgical procedure. The highest level of cholesterol and LDL (6 moths from surgery) is observed in patients who underwent hysterectomy with bilateral oophorectomy.

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