Implementing Disciplines of Neuroeconomics to Study the Causing Factors of Emergence For Adolescent Perturbation and Depression

Major depressive disorder, also known as MDD, is characterized by an extreme sensitivity to negative feedback, possibly related to frontocingulate abnormalities. One of the signs of MDD is a heightened sensitivity to negative input. Electrophysiological responses to negative internal and external inputs are increased in patients with MDD. Using a task requiring probabilistic punishment learning, we explored feedback-related negativity (FRN) in both RD (remitted depressed) and control participants. The bulk of experimental paradigms have been non-social, considering the importance of investigating the functional domain of reward in adolescent depression. In this study, we hypothesize that the processes and concepts of neuroeconomics can fill this gap in the existing scope of research. We will explore a social incentive model that is used to explain teenage depression vulnerability. This model was created to encapsulate how adolescent suicide is more prevalent than adult suicide. Next, we demonstrate how the study of neuroeconomics has the potential to improve the accuracy of this model by providing the means to research the mechanisms of social interactions that either contribute to the maintenance of depression or put individuals at risk for developing it. We offer a neureoeconomic model of adolescent depression as a result. According to this paradigm, depression is a disruption of the incentive and reward exchange that occurs between interpersonal ties. This model is designed to serve as a roadmap for future study.