Predictive value of peak strain dispersion on left ventricular remolding in patients with ST-segment elevation myocardial infarction after primary percutaneous coronary intervention

Background: Left ventricular (LV) remolding is associated with a higher rate of heart failure hospitalization in patients with ST-segment elevation myocardial infraction (STEMI). The aim of the current study was to demonstrate the predictive value of peak strain dispersion (PSD) for LV remodeling. Methods: and results 76 patients with STEMI undergoing primary PCI were prospectively included from June 2019 and August 2020. Patients underwent two-dimensional echocardiography within 48h of admission and 6 months after STEMI. LV remodeling was defined as an increase in the LV end-diastolic volume (LVEDV) ≥ 20% at 6 months after STEMI. According to the echocardiographic criteria used, 13 patients (17.1%) presented with left ventricular remolding after the index event. GLS and myocardial work parameters were similar in patients with left ventricular remolding and those without LV remolding, while patients with left ventricular remolding had a higher PSD than those without remolding (p<0.01). Conclusion: PSD demonstrated incremental value in predicting left ventricular remodeling in STMEI patients undergoing primary PCI.