Therapeutic Effect Of β-Glucan On Ehrlich Ascites Carcinoma That Induced Liver Toxicity

In this study, the protective effects of β-glucan against Ehrlich ascites carcinoma (EAC) induced liver injury, toxicity, and changes in AFP, ANA, and anti-dsDNA are explored. 40 mice were allocated evenly and randomly into 4 groups: Group1, the control group; Group2, the β-glucan group; Group3, the EAC group; and Group4, the EAC+β-glucan group. The most recent findings showed that EAC caused liver damage and elevated levels of serum ALT, AST, ALP, AFP, and anti-dsDNA. The levels of serum total proteins and albumin, however, significantly decreased as compared to the control. β-glucan treatment of EAC improved liver function and structure against EAC. This suggests that β-glucan may be useful in the prevention and management of liver toxicity.