Einfluss einer Langzeit-Hormonsubstitution auf klinische und biochemische Parameter

Cornelia med. Wüstefeld
2006 · W2282013478
dissertation OA: green CC0
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This study evaluated the effects of long-term hormone replacement therapy with Dienogest and natural estrogen versus NETA and estrogen on clinical and biochemical parameters in postmenopausal women.

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The provided “paper body” does not include study content; instead, it contains a website protection message describing an Anubis proof-of-work system that blocks automated access. Because the methods, population, results, and limitations of the underlying research are not present, no biomedical findings about long-term hormone substitution can be extracted or accurately summarized. Therefore, the paper’s key findings cannot be determined from the text provided. The paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Abstract

Der Dissertation liegt eine Studie von Jenapharm zugrunde, in der das neu entwickelte Gestagen Dienogest erstmals bei postmenopausalen Frauen angewandt wurde. Bisher hat Dienogest in der Kontrazeption seine antiandrogene Eigenschaft hervorragend unter Beweis gestellt. Nun wird es in Kombination mit einem natürlichen Estrogen als Climodien® zur Therapie postmenopausaler Beschwerden eingesetzt. Dem gegenüber steht das alt bekannte Präparat Kliogest®, welches mit NETA (Norethisteronacetat) ein Gestagen mit einer androgenen Restwirkung beinhaltet.
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