Lselectin Levels in Patients with Endometriosis
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Abstract
Objective: To investigate the L-selectin profile in endometrioticpatients.Methods: This was a cross-sectional study. Subjects were patientsdiagnosed endometriosis based on clinical examination, transvaginalultrasound, MRI and CT scan at the Department of Obstetricsand Gynecology of Prof. Dr. R.D. Kandou Hospital Manado, SiloamHospital and Network Hospital starting from January 2017 to May2017. The blood samples in patients prior to surgery were taken ona vein and then separated to obtain serum. Further more, serumlevels of L-selectin were measured using enzyme-linked immunosorbentassay (ELISA). Data were analyzed with SPSS version 22.0to see significance level.Results: Of the 18 samples, based on age, endometriosis highest inthe group > 26 years ie 17 patients (94.44%), followed by the agegroup of 21-25 years in 1 patient (5:56%), and none of thepatients in the age group 4 (0%). Based on the highest stage is thethird stage as many as 11 people (61.11%), followed by stage 4 of7 patients (38.99%), and none of the patients in stage 1 or stage 2(0%). From a statistical test used to stage endometriosis age, theT test, p value 0.286. From a statistical test according to the levelsof L-selectin on endometriosis stadium used, the T test, p value0.090. Results of correlation tests were used, namely statingPearson test p value of 0.921.Conclusion: L-selectin levels in women with endometriosisincreased according to clinical stage, but not significant in statisticaltests. There is no significant relationship between age withstages or levels of L-selectin in women with endometriosis.Keywords: adhesion, age, endometriosis, L-selectin, stage
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Objective
To investigate the L-selectin profile in endometriotic
patients.
Methods
This was a cross-sectional study. Subjects were patients
diagnosed endometriosis based on clinical examination, transvaginal
ultrasound, MRI and CT scan at the Department of Obstetrics
and Gynecology of Prof. Dr. R.D. Kandou Hospital Manado, Siloam
Hospital and Network Hospital starting from January 2017 to May
2017. The blood samples in patients prior to surgery were taken on
a vein and then separated to obtain serum. Further more, serum
levels of L-selectin were measured using enzyme-linked immunosorbent
assay (ELISA). Data were analyzed with SPSS version 22.0
to see significance level.
Results
Of the 18 samples, based on age, endometriosis highest in
the group > 26 years ie 17 patients (94.44%), followed by the age
group of 21-25 years in 1 patient (5:56%), and none of the
patients in the age group 4 (0%). Based on the highest stage is the
third stage as many as 11 people (61.11%), followed by stage 4 of
7 patients (38.99%), and none of the patients in stage 1 or stage 2
(0%). From a statistical test used to stage endometriosis age, the
T test, p value 0.286. From a statistical test according to the levels
of L-selectin on endometriosis stadium used, the T test, p value
0.090. Results of correlation tests were used, namely stating
Pearson test p value of 0.921.
Conclusion
L-selectin levels in women with endometriosis
increased according to clinical stage, but not significant in statistical
tests. There is no significant relationship between age with
stages or levels of L-selectin in women with endometriosis.
Keywords
adhesion, age, endometriosis, L-selectin, stage
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