Bacterial efflux pumps excrete SYTO™dyes from bacteria and lead to false-negative staining results
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Abstract
Multidrug efflux pumps excrete a range of small molecules from bacterial cells. In this study, we show that bacterial efflux pumps have affinity for a range of SYTO™ dyes that are commonly used to label bacteria. Efflux pump activity will there lead to false negative results from bacterial staining and SYTO™ dyes should be used with caution on live samples. Abstract Figure
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- last seen: 2026-05-19T01:45:01.086888+00:00