Optimal use of postmenopausal hormone replacement

The well-informed physician can use the following specific strategies to help postmenopausal women obtain maximum benefit from estrogen therapy: 1) choosing the woman most likely to benefit; 2) initiating therapy at a time when it will do the most good; 3) tailoring treatment to maximize safety, efficacy, and acceptability; and 4) fostering patient commitment to long-term treatment through education, monitoring, and supportive counseling.