Shrinkage of uterine fibroids by preoperative LHRH analogue injection.
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AI-generated summary
Preoperative goserelin implants reduced uterine fibroid volume by 30-47% and alleviated symptoms in six patients, indicating potential utility for shrinking fibroids prior to hysterectomy.
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Abstract
Six patients with large uterine fibroids were given a single subcutaneous implant of an LHRH analogue (goserelin 3.5 mg) prior to elective hysterectomy. Overall fibroid volume decreased by 30-47% within six weeks of implantation. All patients reported improvement in their symptoms of pressure and pain, and were rendered amenorrhoeic prior to surgery.
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- europepmc
- last seen: 2026-09-06T09:34:12.023084+00:00