⚙
AI-generated deep summary
by qwen3.7-flash, 2026-09-24
· read from full text
ⓘ
This figure illustrates differences in endometrial vasculature and decidualization markers between fertile and infertile women undergoing assisted reproductive technologies. Immunostaining for CD34 reveals that successful pregnancies are associated with small, compact blood vessels, whereas enlarged vessels correlate with stimulation protocols and failure to conceive. Concurrently, intense stromal prolactin staining indicates premature decidualization in non-pregnant subjects, while successful implantation is linked to glandular rather than stromal prolactin expression. The paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.
Abstract
Blood vessels within the endometria of fertile women at LH+2 were generally small and compact (A). Examination of endometria from fertile women stimulated with the GnRH agonist protocol for ovum donation at hCG+2 revealed a mixture of small blood vessels and grossly enlarged blood vessels (B, arrow). Endometria from infertile women stimulated with the GnRH antagonist protocol at hCG+2 revealed a mixed picture of vascular development, with some endometria presenting grossly enlarged blood vessels (C, arrow) whereas some presented with small compact blood vessels (D). Women stimulated with the GnRH agonist protocol at hCG+2 who did not subsequently become pregnant presented with large endometrial blood vessels (E), whereas women stimulated with this protocol who did become pregnant generally presented with smaller more compact blood vessels (F). Fertile women at LH+2 had little to no immunostaining for prolactin within the endometrial stromal compartment (G). Some areas within the endometria of fertile women stimulated with the GnRH protocol for ovum donation (H), infertile women stimulated with the GnRH antagonist protocol (I) and infertile women stimulated with the GnRH agonist protocol who did not become pregnant (J) at hCG+2 demonstrated intense stromal prolactin immunostaining indicative of decidual changes. Endometria from infertile women stimulated with the GnRH agonist protocol at hCG+2 who subsequently became pregnant (K) demonstrated little stromal prolactin immunostaining, but did demonstrate glandular prolactin immunostaining indicative of secretory changes (K, arrows).
Full text
1,781 characters
· extracted from
oa-doi-fallback
· click to expand
Defective Soil for a Fertile Seed? Altered Endometrial Development Is Detrimental to Pregnancy Success
Figure 4
Vasculature/CD34 and decidualization/prolactin immunostaining.
Blood vessels within the endometria of fertile women at LH+2 were generally small and compact (A). Examination of endometria from fertile women stimulated with the GnRH agonist protocol for ovum donation at hCG+2 revealed a mixture of small blood vessels and grossly enlarged blood vessels (B, arrow). Endometria from infertile women stimulated with the GnRH antagonist protocol at hCG+2 revealed a mixed picture of vascular development, with some endometria presenting grossly enlarged blood vessels (C, arrow) whereas some presented with small compact blood vessels (D). Women stimulated with the GnRH agonist protocol at hCG+2 who did not subsequently become pregnant presented with large endometrial blood vessels (E), whereas women stimulated with this protocol who did become pregnant generally presented with smaller more compact blood vessels (F). Fertile women at LH+2 had little to no immunostaining for prolactin within the endometrial stromal compartment (G). Some areas within the endometria of fertile women stimulated with the GnRH protocol for ovum donation (H), infertile women stimulated with the GnRH antagonist protocol (I) and infertile women stimulated with the GnRH agonist protocol who did not become pregnant (J) at hCG+2 demonstrated intense stromal prolactin immunostaining indicative of decidual changes. Endometria from infertile women stimulated with the GnRH agonist protocol at hCG+2 who subsequently became pregnant (K) demonstrated little stromal prolactin immunostaining, but did demonstrate glandular prolactin immunostaining indicative of secretory changes (K, arrows).
Text is read by the "Ask this paper" AI Q&A widget below.
Extraction quality varies by source — PMC NXML preserves structure
cleanly, OA-HTML may include some navigation residue, and OA-PDF can
have broken hyphenation. The publisher copy
(via DOI)
is the canonical version.