Hysteroscopic endometrial ablation as a treatment for abnormal uterine bleeding in patients with renal transplants

Jeong KA, Kyung-Ah Jeong, Ki Hyun Park, Park KH, Da Jung Chung, Chung DJ, Shin JS, Jong Seung Shin, Sang Wook Bai, Byung Seok Lee, Dong Jae Cho, Cho DJ, Chan Ho Song, Song CH
The Journal of the American Association of Gynecologic Laparoscopists · 2004 · vol. 11(2) , pp. 252–255 · doi:10.1016/s1074-3804(05)60209-5 · PMID:15200785 · W1969455658
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This paper describes hysteroscopic endometrial ablation as a treatment option for abnormal uterine bleeding in patients who have received kidney transplants.

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Abstract

STUDY OBJECTIVE: To assess the effectiveness and safety of hysteroscopic endometrial ablation as a surgical management of abnormal uterine bleeding that develops in patients with renal transplants. DESIGN: Retrospective study (Canadian Task Force classification II-2). SETTING: Yonsei University Medical College, Severance Hospital. PATIENTS: Sixty-two women with abnormal uterine bleeding who had undergone renal transplantation. INTERVENTION: Hysteroscopic endometrial ablation. MEASUREMENTS AND MAIN RESULTS: Fifty-four out of 62 patients (87.0%) who had undergone hysteroscopic endometrial ablation reported decreased bleeding (95% CI: 0.76 to 0.94): amenorrhea in 25 (40.3%), spotting in 19 (30.6%), and eumenorrhea in 10 (16.1%). Mean follow-up duration was 6 months. No complications related to the procedure were reported. Levonorgestrel-releasing intrauterine systems (LNG-IUSs) were inserted into eight patients who experienced continuous bleeding, five of whom showed symptomatic improvement: spotting in three (4.9%) and eumenorrhea in two (3.2%). The three patients (4.9%) in whom the LNG-IUS had no effect had hysterectomies, and the resultant pathologic findings were two cases of adenomyosis and one case of simple endometrial hyperplasia without atypia. CONCLUSION: Hysteroscopic endometrial ablation as a surgical management of abnormal uterine bleeding that develops in patients with renal transplants is an effective and safe procedure.

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MeSH descriptors

Hysteroscopy Kidney Failure, Chronic Kidney Transplantation Kidney Transplantation Menorrhagia Adult Adult Cohort Studies Cohort Studies Confidence Intervals Confidence Intervals Electrocoagulation Electrocoagulation Electrocoagulation Endometrium Endometrium Endometrium Female Female Follow-Up Studies

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