[Psychosomatic aspects and antipsychotics medication in ethiopathogenesis of endometrial carcinoma].

OBJECTIVE: To assess possible role of psychosomatic aspects and antipsychotic medical treatment in ethio-pathogenesis of endometrial cancer. DESIGN: Prospective study and revue of literature. SETTING: Department of Obstetrics and Gynecology, Faculty of Medicine and Dentistry, University Hospital, Olomouc; Department of Health Care Science, Faculty of Humanities, Tomas Bata University in Zlín. METHODS: A case-control study was conducted on 40 patients who underwent surgical treatment for histopathologicly confirmed diagnosis of endometrial cancer. Patients on admition were examined by means of the standardised Minnesota personality inventory MMPI-2. Antipsychotic medical treatment in patients history was recorded. RESULTS: Our study confirmed signinicantly increas in the scale of depression, anxiety, psychastenia, social introversion, low self-respect, A-type behaviour and hostility. On the other hand there were no changes in the scale of hysteria and lie. A possible role of antipsychotics is discussed. KEYWORDS: endometrial carcinoma, psychosomatic aspects, antipsychotics medication.