Study of thymol bioformulations with potential phytosanitary application | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Study of thymol bioformulations with potential phytosanitary application SEBASTIAN E RAMOS, M. CAROLINA PAZOS, MARIA D ALBA This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-8722570/v1 This work is licensed under a CC BY 4.0 License Status: Under Review Version 1 posted 5 You are reading this latest preprint version Abstract The essential oil (EO) of thyme ( Thymus vulgaris ) exhibits antifungal and antimicrobial properties. Its high concentration of terpenes, such as thymol, provides them with great effectiveness as a fungicide, particularly against fungi such as Moniliophthora roreri , a cocoa pathogen. However, its potential application as an organic fungicide is limited by the photostability and volatilization of essential oils. Thus, the use of carriers for the extract has been the aim of this research. In this study, the adsorption-desorption process of thymol has been evaluated in calcium alginate-bentonite microcapsules and the bentonite-chitosan composite as EO carriers. The results have shown that the maximum adsorption capacity was higher for the microcapsules than for the organoclays. However, the desorption percentages indicated that organoclays showed the most adequate release. Finally, the water activity values generated by both bioformulations were below 0.6, indicating that carriers can reduce the probability of microbial growth. Phytosanitary Microcapsules Organoclay Thyme Chitosan Full Text Supplementary Files Supplementarymaterialsv3.docx Cite Share Download PDF Status: Under Review Version 1 posted Reviewers agreed at journal 26 Mar, 2026 Reviewers invited by journal 05 Mar, 2026 Editor invited by journal 29 Jan, 2026 Editor assigned by journal 29 Jan, 2026 First submitted to journal 28 Jan, 2026 You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. 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