Does Obesity Impact Assisted Reproductive Outcomes in Patients with Endometriosis?

Aim: It is not known whether overweight or obese women with endometriosis have the same outcomes of in vitro fertilization (IVF) when compared with normal weight patients. In the present study, we aimed to evaluate the impact of obesity on assisted reproductive outcomes in patients with endometriosis. Material and Method: A total of 45 women with a history of endometrioma operation who underwent IVF or ICSI treatment from 2009 to 2014 in our center were included in this retrospective cohort study. The patients were divided into two groups according to their body mass index (BMI): Group 1 was composed of 15 patients with a BMI of %≥25 kg/m2; group 2 included 30 normal weight women (18.5-25 kg/m2). IVF/ICSI characteristics and outcomes were analyzed. Only fresh cycles were included. Women over the age of 38 were excluded. BMI was calculated by using height and weight information from the medical records. Results: There were no significant differences between the groups regarding mean age, basal FSH, and basal LH. The overweight and obese patients had similar numbers of oocytes retrieved (p=0.739), metaphase 2 oocytes (p=0.680), and peak estradiol levels on HCG administra¬tion day (p=0.751) compared with the normal weight patients. The clinical pregnancy rate was also similar in the two groups. Discussion: BMI does not seem to affect IVF/ICSI characteristics and outcomes in patients with a history of endometrioma operations.