Heading direction with respect to a reference point modulates place-cell activity

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Abstract

Utilizing electrophysiological recordings from CA1 pyramidal cells in freely moving mice, we find that a majority of neural responses are modulated by the heading-direction of the animal relative to a point within or outside their enclosure that we call a reference point. Our findings identify a novel representation in the neuronal responses in the dorsal hippocampus.

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europepmc
last seen: 2026-05-19T01:45:01.086888+00:00