Characterization of 100 sequential SARS-CoV-2 convalescent plasma donations

2020 · doi:10.1101/2020.06.21.163444
preprint OA: gold CC-BY-NC-ND-4.0
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This study characterized 100 SARS-CoV-2 convalescent plasma donations to identify donor characteristics and inform effective collection strategies for potent plasma.

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Abstract

Transfusion of SARS-CoV-2 convalescent plasma is a promising treatment for severe COVID-19 cases, with success of the intervention based on neutralizing antibody content. Measurement by serological correlates without biocontainment needs, and an understanding of donor characteristics that may allow for targeting of more potent donors would greatly facilitate effective collection.

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europepmc
last seen: 2026-05-19T01:45:01.086888+00:00
unpaywall
last seen: 2026-05-21T05:10:58.409756+00:00
License: CC-BY-NC-ND-4.0