Distribution and antimicrobial resistance of Acinetobacter spp. isolated from different types of infections from hospitalized patients and outpatients in Poland

Distribution and antimicrobial resistance of Acinetobacter spp. isolated from different types of infections from hospitalized patients and outpatients in Poland | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Distribution and antimicrobial resistance of Acinetobacter spp. isolated from different types of infections from hospitalized patients and outpatients in Poland Kasperski Tomasz, Pobiega Monika, Pomorska-Wesołowska Monika, and 2 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-5821427/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Background: Acinetobacter baumannii (AB) is the most frequently isolated nosocomial pathogen, but severe infections by A. pittii , A. ursingii , and A. bereziniae are increasing. This study investigated the distribution and antibiotic resistance of Acinetobacter spp. strains from various infections. Methods: Data were collected between 2021–2023 from clinical samples of hospitalized and outpatient individuals in southern Poland. Strains were identified using MALDI-TOF Biotyper, and antibiotic susceptibility was tested with the MIDITECH-Analyzer system. Statistical analyses were conducted using IBM SPSS Statistics. Results: Among 1507 isolated Acinetobacter strains, 951 (63.1%) were AB, while 556 (36.9%) represented 27 non-AB species. Most isolates (73.6%) came from outpatients, while 26.4% were from hospitalized patients. A. ursingii (30.2%), A. pittii (20.6%), and A. junii (13%) were the most common non-AB species. A. bereziniae , A. calcoaceticus , and A. proteolyticus were more frequently found in hospitalized patients. Non-AB species dominated in/among genital tract infections (87%), whereas AB was more common in invasive infections. Nearly all strains were non-susceptible to ciprofloxacin (98.4%), with lower resistance rates to ampicillin/sulbactam (11.1%), trimethoprim/sulfamethoxazole (5.8%), gentamicin (2.9%), amikacin (2.5%), meropenem (1.6%), and colistin (1.6%). A. bereziniae showed frequently resistance to carbapenems, aminoglycosides, and trimethoprim/sulfamethoxazole. Colistin resistance was observed in A. ursingii and A. pittii . Conclusions: While AB accounted for 63.1% of isolates, non-AB species were common, particularly in genitourinary and skin infections. Emerging hospital-acquired infections by species like A. pittii underline the need for vigilant monitoring. The high resistance to ciprofloxacin and low but noticeable resistance to carbapenems and colistin highlights the importance of early detection and resistance surveillance to prevent the spread of resistant strains. Acinetobacter spp. antimicrobial resistance genitourinary infections skin and soft tissue infections colistin Figures Figure 1 Figure 2 Figure 3 Introduction Acinetobacter , a genus consisting of biochemically and physiologically versatile Gram-negative coccobacilli that are distributed in nature, may play an important role in opportunistic human infections. This genus is characterized as aerobic, nonfermenting, nonfastidious, immobile, catalase-positive, and oxidase-negative bacteria ( 1 ). The taxonomy of the genus currently consists of 85 distinct validly named species ( 2 , 3 ). On the basis of the genomic analyses, new individual species are still being distinguished, characterized by genomic distinctness and monophyly. The last species to be fully validated are Acinetobacter suaedae and Acinetobacter oleivorans ( 4 , 5 ). Among this genus, A. baumannii (AB) is the most frequently isolated nosocomial pathogen and is considered the most clinically relevant, followed by other members of the Acinetobacter baumannii - calcoaceticus complex (Abc) ( A. calcaoaceticus , A. pitti , A. nosocomialis , A. seifertti , A. dijkshoorniaem ) ( 6 , 7 ). There are also reports of less common but still important and serious infections caused by Acinetobacter ursingii , Acinetobacter haemolyticus , Acinetobacter lwoffii , Acinetobacter parvus , and Acinetobacter junii ( 8 – 13 ). Human infections caused by A. lwoffii , A. courvalinii , A. johnsonii , and A. bereziniae have been recognized recently by using new diagnostic methods ( 14 – 16 ). Acinetobacter spp. are also involved in cases of coinfection with SARS-CoV-2 ( 15 , 16 ) A. pittii is associated with hospital-acquired infections, such as bloodstream infections, ventilator-associated pneumonia, and wound infections ( 18 , 19 ). There are reports from France and Germany showing that A. pittii is the most common Acinetobacter species isolated ( 20 , 21 ). A. ursingii has been reported as a cause of infections (including bacteremia) in the Netherlands, Japan and the pediatric ward in Argentina ( 22 – 24 ). A. junii was reported as a cause of bacteremia, ocular infection and an outbreak in the neonatal ward ( 25 – 27 ) Multidrug-resistant (MDR) bacteria currently cause over 700,000 deaths each year, and it is estimated that this number could rise to 10 million by 2050 ( 28 ). The World Health Organization (WHO) highlights AB as one of the top antibiotic-resistant "priority pathogens", for which the development of new antibiotics is urgently needed ( 29 ). This phenomenon is associated with a high mortality rate of Acinetobacter infection, ranging from 45 to 70% ( 30 , 31 ), and easy transfer of antibiotic resistance genes among Acinetobacter species, which leads to the emergence of multidrug-resistant pathogens, resulting in the use of few antimicrobial agents ( 32 , 33 ). Moreover, Acinetobacter spp. have intrinsic antimicrobial resistance mechanisms that are expressed constitutively or in response to antibiotics in the environment. The greatest concern is carbapenem resistance, as those antimicrobials are considered last-resort in the treatment of infections caused by resistant strains. Carbapenem resistance in non- A. baumannii (non-AB) species is driven by a variety of oxacillinases, as in A. baumannii . However, genes encoding metallo-beta-lactamases such as NDM and IMP have also been identified in other Acinetobacter species, including A. bezeriniae , A. ursingii , A. pittii , and A. lwoffii , among others ( 24 , 34 , 35 ). Carbapenem resistance is often associated with resistance to other antibiotics. Pandrug-resistant strains have been found among A. pittii strains ( 36 ). In addition to being drug resistant, Acinetobacter is characterized by high virulence; AB is perceived as the most virulent one, followed by A. calcoaceticus and A. lwoffii ( 37 – 39 ). In addition to the growing concerns of carbapenem resistance in Acinetobacter species, the increasing frequency of Acinetobacter infections in hospital settings highlights the importance of surveillance and antibiotic stewardship. The resistance mechanisms of Acinetobacter species, together with their ability to acquire further resistance through horizontal gene transfer, contribute to their persistence in healthcare environments. Given their ability to form biofilms and adapt to hostile environments, Acinetobacter spp. are notorious for causing challenging infections in both hospital and community settings ( 40 ). It is essential to monitor the epidemiology, resistance profiles, and virulence of Acinetobacter spp. to develop effective treatment strategies and prevent the further spread of multidrug-resistant strains. The aim of this study was to investigate the distribution and antibiotic resistance patterns of Acinetobacter spp. strains isolated from various types of infections in both hospitalized patients and outpatients in southern Poland. Materials and methods 2.1 Patient population The bacterial strains were collected between January 2021 and December 2023 from all clinical materials during routine diagnosis from patients hospitalized at 13 hospitals and from 30 outpatient departments of Silesian Province (mainly Katowice, Sosnowiec, Ruda Śląska, Piekary Śląskie, Świętochłowice, Knurów, etc.) and Opolskie Province (Opole, Głuchołazy) in southern Poland. The locations of outpatient departments and hospitals are shown on the map of southern Poland (Figure 1). The data were collected and analyzed in cooperation with the KORLAB Laboratory in Ruda Śląska. All patients' data were anonymized before the analysis was conducted. The strains were selected according to the following criteria: (i) belonging to the Acinetobacter genus (infections caused by AB were analyzed for comparative purposes, but AB was excluded from the detailed study), (ii) nonduplicate samples, and (iii) were isolated from different patients. The strains were collected in accordance with the consent of the Bioethics Committee of Jagiellonian University KBET 1072.6120.274.2021. 2.2. Bacterial isolates Bacterial cultures were grown overnight on Columbia sheep blood agar (Becton Dickinson, Heidelberg, Germany) at 37°C. The isolates were identified via an automated MALDI-TOF Biotyper system (matrix-assisted laser desorption/ionization with a time-of-flight analyzer) with the mass spectral library MBT IVD LIBRARY (Bruker, Billerica, Massachusetts, United States). 2.3. Antimicrobial susceptibility testing Antibiotic susceptibility was determined on the basis of the results of an automated MIDITECH Analyzer v.12 system for ampicillin/sulbactam; imipenem; meropenem; amikacin; gentamicin; tobramycin ciprofloxacin; trimethoprim/sulfamethoxazole; and colistin. The results were interpreted using the clinical breakpoints defined in the latest EUCAST guidelines—v. 14.0 (41). For ampicillin/sulbactam, the interpretation was made on the basis of Clinical and Laboratory Standards Institute (CLSI) guidelines (42). The MIC for colistin was confirmed using the microdilution method (MIC STRIPPED PLATES COL; Diagnostics, Slovakia), and the results were interpreted in line with the manufacturer’s instructions according to EUCAST v. 14.0 (41). As nonsusceptible strains, strains resistant to and with intermediate susceptibility were identified. 2.4. Statistics To evaluate the relationship between the occurrence of AB infections and non-AB infections in the context of primary infection types, a chi-square test of independence was conducted. Crosstabulations were constructed to present the observed frequencies for each combination of variables, and the chi-square statistic was calculated. Symmetric measures, such as the contingency coefficient, were also calculated to evaluate the strength of the association. The relationship between the year of isolation and resistance to the tested antibiotics was analyzed via Fisher's exact test. To analyze the associations between Acinetobacter species and healthcare settings (hospitals vs. outpatient clinics), Fisher's exact test was used across all datasets for consistency. The analysis included species with sufficient sample sizes (n ≥ 10): Acinetobacter ursingii, Acinetobacter pittii, Acinetobacter junii, Acinetobacter lwoffii, Acinetobacter bereziniae, Acinetobacter radioresistens, Acinetobacter lactucae (syn. A. dijkshoorniae ), and Acinetobacter calcoaceticus . Species with fewer than 10 isolates were excluded because of insufficient data for reliable statistical testing. To assess the associations between bacterial species and infection types, Fisher's exact test was applied. This test was chosen to evaluate the relationships among all species and infection types comprehensively. Pairwise Fisher's exact tests were conducted for each combination of organism and infection type, producing p values indicating statistical significance. All analyses were performed via IBM SPSS Statistics (v. 29.0.2.0). Results In total, 1507 strains belonging to the Acinetobacter genus were isolated between 2021 and 2023 from patients with different types of infections. Of these, 951 (63.1%) belonged to the Acinetobacter baumannii species, whereas 556 (36.9%) belonged to other Acinetobacter species. In 2021, 494 strains were isolated (AB: 348 (70.4%), non-AB 146: (29.6%)); in 2022, 499 strains were isolated (AB: 285 (57.1%), non-AB:214 (42.9%)); and in 2023, 514 strains were isolated (AB: 318 (61.9%), non-AB: 196 (38.1%)). Among all non-AB strains, 148 (26.6%) were isolated from hospital patients, whereas 408 strains (73.4%) were isolated from outpatients. For 109 of all the non-AB isolated strains, susceptibility testing was not performed (due to the high number of other bacterial species isolated from the sample or classification of the isolated strain identified as part of the physiological flora without clinical significance). Therefore, a total of 447 strains were included in the final analysis of this study, comprising 123 strains from 2021, 171 from 2022, and 153 from 2023. Among these strains, 118 strains (26.4%) came from hospitalized patients, whereas 329 (73.6%) were from outpatients (Table 1). The median age of the patients, of whom 53% (n=237) were women, was 58 years (Q1=37, Q3=72 years). The region of origin of the isolates and their distribution per hospital are displayed in Figure 1. Among all the samples, in 171, only one strain was isolated (monoculture). In the remaining 276 samples, other accompanying stains were identified. Overall, the highest number of infections caused by non-AB strains (n=132) was associated with Gram-positive cocci, primarily Enterococcus faecalis . In 82 patients, the accompanying flora consisted of Enterobacterales, whereas in 47 patients, nonfermenting rods were identified. The highest prevalence of accompanying flora was observed in skin and soft tissue infections (SSTI), where in 71.6% of cases, non-AB strains were accompanied by other species. In total, 27 non-AB species were identified. The majority of strains were A. ursingii species (n=135, 30,2%), followed by A. pittii (n=92, 20,6%) and A. junii (n=58, 13%). The highest number of non-AB strains was isolated in 2022 (n=171, 38.3%). The species more frequently isolated from hospitalized patients than from outpatients were A. bereziniae , A. calcoaceticus , and A. proteolyticus . A detailed breakdown of the isolated species can be found in Table 1 Table 1. Species isolated from infections from hospitalized patients and outpatients b y year. Species Number of all isolates N 100% Year of isolation Unit Number of isolates qualified to analysis N 100% Year of isolation Unit 2021 n (%) 2022 n (%) 2023 n (%) Hospital n (%) Outpatients n (%) 2021 n (%) 2022 n (%) 2023 n (%) Hospital n (%) Outpatients n (%) Acinetobacter ursingii 164 50 (30.5) 70 (42.7) 44 (26.8) 24 (14.7) 140 (85.3) 135 43 (31.8) 56 (41.5) 36 (26.7) 18 (13.3) 117 (86.6) Acinetobacter pittii 111 25 (22.5) 48 (43.2) 38 (34.2) 35 (31.5) 76 (68.5) 92 20 (21.7) 40 (43.5) 32 (34.8) 27 (29.3) 65 (70.6) Acinetobacter junii 63 16 (25.4) 28 (44.4) 19 (30.2) 9 (14.3) 54 (85.7) 58 15 (25.9) 26 (44.8) 17 (29.3) 9 (15.5) 49 (84.5) Acinetobacter lwoffii 52 13 (25.0) 19 (36.5) 20 (38.5) 22 (42.3) 30 (57.7) 37 11 (29.7) 12 (32.4) 14 (37.8) 17 (45.9) 20 (54.0) Acinetobacter bereziniae 26 12 (46.2) 8 (30.8) 6 (23.0) 16 (61.5) 10 (38.5) 22 9 (40.9) 6 (27.3) 7 (31.8) 14 (63.6) 8 (36.3) Acinetobacter radioresistens 21 5 (23.8) 8 (38.1) 8 (38.1) 5 (23.8) 16 (76.2) 19 4 (21.0) 8 (42.1) 7 (36.8) 5 (26.3) 14 (73.7) Acinetobacter lactucae (synonym dijkshoorniae) 21 3 (14.3) 7 (33.3) 11 (52.4) 4 (19.0) 17 (81.0) 14 2 (14.3) 5 (35.7) 7 (50.0) 3 (21.4) 11 (78.6) Acinetobacter calcoaceticus 19 2 (10.5) 6 (31.6) 11 (57.9) 9 (47.4) 10 (52.6) 15 1 (6.7) 5 (33.3) 9 (60.0) 9 (60.0) 6 (40.0) Acinetobacter proteolyticus 11 5 (45.5) 4 (36.4) 2 (18.2) 5 (45.5) 6 (31.6) 8 4 (50.0) 3 (37.5) 1 (12.5) 5 (62.5) 3 (37.5) Acinetobacter hemolyticus 11 4 (36.4) 7 (63.6) 0 3 (27.3) 8 (72.7) 7 3 (42.8) 4 (57.1) - 2 (28.6) 5 (71.4) Acinetobacter johnsonii 10 1 (10.0) 4 (40.0) 5 (50.0) 1 (10.0) 9 (90.0) 6 1 (16.7) 2 (33.3) 3 (50.0) 1 (16.7) 5 (83.3) Acinetobacter soli 6 0 0 6 (100.0) 0 6 (100.0) 5 - - 5 (100.0) - 5 (100.0) Acinetobacter guillouiae 9 1 (11.1) 0 8 (88.9) 3 (33.3) 6 (66.6) 5 1 (20.0) - 4 (80.0) 1 (20.0) 4 (80.0) Acinetobacter noscomialis 6 5 (83.3) 0 1 (16.7) 2 (33.3) 4 (66.6) 5 5 (100.0) - - 2 (40.0) 3 (60.0) Acinetobacter towneri 3 2 (66.6) 0 1 (33.3) 1 (33.3) 2 (66.6) 3 2 (66.6) - 1 (33.3) 1 (33.3) 2 (66.6) Acinetobacter schindleri 3 0 2 (66.6) 1 (33.3) 1 (33.3) 2 (66.6) 3 - 2 (66.6) 1 (33.3) 1 (33.3) 2 (66.0) Acinetobacter variabilis 3 0 1 (33.3) 2 (66.6) 2 (66.6) 1 (33.3) 2 - - 2 (100.0) 1 (50.0) 1 (50.0) Acinetobacter venetianus 2 0 0 2 (100.0) 0 2 (100.0) 2 - - 2 (100.0) 0 2 (100.0) Acinetobacter dispersus 4 0 0 4 (100.0) 3 (75.0) 1 (25.0) 2 - - 2 (100.0) 1 (50.0) 1 (50.0) Acinetobacter parvus 1 1 (100.0) 0 0 0 1 (100.0) 1 1 (100.0) - - 0 1 (100.0) Acinetobacter kookii 1 0 0 1 (100.0) 0 1 (100.0) 1 - - 1 (100.0) 0 1 (100.0) Acinetobacter modestus 1 0 0 1 (100.0) 0 1 (100.0) 1 - - 1 (100.0) 0 1 (100.0) Acinetobacter gyllenbergii 2 0 0 2 (100.0) 2 (100.0) 0 1 - - 1 (100.0) 1 (100.0) 0 Acinetobacter beijerinckii 1 0 1 (100.0) 0 0 1 (100.0) 1 - 1 (100.0) - 0 1 (100.0) Acinetobacter indicus 1 1 (100.0) 0 0 0 1 (100.0) 1 1 (100.0) - - 0 1 (100.0) Acinetobacter seifertii 2 0 1 (50.0) 1 (50.0) 1 (50.0) 1 (50.0) 1 - 1 (100.0) - 0 1 (100.0) Acinetobacter colistiniresistens 1 0 0 1 (100.0) 0 1 (100.0) 0 0 0 0 0 0 Acinetobacter defluvii 1 0 0 1 (100.0) 0 1 (100.0) 0 0 0 0 0 0 Total 556 (100) 146 (26,3) 214 (38,5) 196 (35,2) 148 (26,6) 408 (73,4) 447 (100) 123 (27,5) 171 (38,3) 153 (34,2) 118 (26,4) 329 (73,6) A statistically significant association was observed between Acinetobacter ursingii and Acinetobacter pittii , with A. ursingii being more prevalent in outpatient clinics (86.6%) than A. pittii (70.6%) (p=0.003). Similarly, A. ursingii was significantly associated with outpatient settings compared with Acinetobacter bereziniae (36.3%), which was more frequently isolated in hospitals (p<0.001). Significant differences were also noted between A. ursingii and Acinetobacter calcoaceticus , where A. calcoaceticus was predominantly found in hospitals (60.0%) (p=0.003). For other comparisons, such as A. ursingii vs. A. lwoffii or A. pittii vs. A. junii , no statistically significant differences were detected in their distributions between hospitals and outpatient clinics (p>0.05). Species with fewer than 10 isolates were excluded from the analysis because of insufficient sample size. Among all the samples, 213 non-AB strains were obtained from genitourinary tract infections, 155 from skin and soft tissue infections (SSTIs), 43 from invasive infections (including 20 strains from bloodstream infections) and 36 from other types of infections. Among 951 AB strains, 387 were from SSTIs, 371 from invasive infections, 181 from genitourinary tract infections and 9 from other types of infections. Non-AB strains (87%) dominated AB strains (13%) in genital tract infections, whereas AB strains were more prevalent in invasive infections, accounting for 90% of lower respiratory tract infections and 90% of bloodstream infections (BSIs). A comprehensive overview of the proportions for each infection type is provided in Table 2. The relative frequency according to the type of infection is shown in Figure 2. A statistically significant relationship was found between the presence of AB and primary infection type, as determined by the chi-square test of independence (χ²(3) = 228.891, p < 0.001). The observed frequencies indicated that AB were predominantly associated with invasive infections (n=374, 39.3%) and SSTIs (n=387, 40.7%), whereas non-AB species were more frequently observed in the genitourinary tract category (n=213, 47.7%). The contingency coefficient was 0.375 (p < 0.001), suggesting a moderate association between the variables. Additional correlation analysis revealed weak yet statistically significant inverse associations, with Pearson’s R and Spearman’s correlation coefficients of -0.109 and -0.110, respectively (p < 0.001). Table 2. Isolates from different types of infections from patients by year. Infection type non A. baumannii baumannii % of non-AB in total number of Acinetobacterspp . strains 2021 2022 2023 total 2021 2022 2023 total n % n % n % n n % n % n % n Genitourinary infections 213 Genitourinary infections 181 54% Urinary tract infection 36 28% 52 41% 39 31% 127 61 36% 52 31% 55 33% 168 43% Genital tract infection 27 31% 32 37% 27 31% 86 5 38% 2 15% 6 46% 13 87% SSTI 155 SSTI 387 29% Wounds infection 27 25% 40 37% 42 39% 109 58 21% 104 38% 109 40% 271 29% Skin infection 8 36% 7 32% 7 32% 22 4 12% 11 32% 19 56% 34 39% Ulcers 5 21% 11 46% 8 33% 24 23 28% 30 37% 29 35% 82 23% Invasive infections 43 Invasive infections 374 10% Respiratory tract infection 7 33% 8 38% 6 29% 21 115 59% 33 17% 47 24% 195 10% Bloodstream infection 5 25% 10 50% 5 25% 20 78 40% 53 27% 48 25% 179 10% Central nervous system infection - - - - 2 100% 2 0 0% 0 0% 0 0% 0 100% Others 36 Others 9 80% Ears infection 4 19% 7 33% 10 48% 21 4 50% 0 0% 4 50% 8 72% Eye infection 3 21% 4 29% 7 50% 14 0 0% 0 0% 1 100% 1 93% Arthritis infection 1 100% - - - - 1 0 - 0 - 0 - 0 100% Legend: non-AB- non-A. baumannii; SSTI – skin and soft tissue infections . The percentage in each column represents the proportion of strains isolated in a given year relative to the total number of strains isolated from the same type of infection across all years. Table 3 presents the distributions of individual species in relation to the type of infection. A. ursingii predominated in genitourinary infections (n=80, 37.6%), followed by A. junii (n=38, 17.8%). Similarly, among the SSTIs, A. ursingii (n=41, 26.5%) was the most common, followed by A. pittii (n=39, 25.2%). The pattern was different for invasive infections, where A. pittii (n=13, 30.2%) was dominant, followed by A. lwoffii (n=7, 16.3%) and A. bereziniae (n=7, 16.3%). The most common strains among bloodstream infections (n=20) were A. lwoffii and A. pittii , which were each isolated from 5 (25%) cases of BSI. Table 3. Distribution of individual species in relation to the type of infection. Infection type Genitourinary tract infections SSTI Invasive infections Others Total Species 213 155 43 36 447 100% Acinetobacter ursingii 80 41 3 11 135 30,2% Acinetobacter pittii 35 39 13 5 92 20,6% Acinetobacter junii 38 11 3 6 58 13,0% Acinetobacter lwoffii 18 10 7 2 37 8,3% Acinetobacter bereziniae 4 7 7 4 22 4,9% Acinetobacter radioresistens 9 9 - 1 19 4,3% Acinetobacter calcoaceticus 4 7 4 - 15 3,4% Acinetobacter lactucae (synonym dijkshoorniae) 4 6 2 2 14 3,1% Acinetobacter proteolyticus 2 4 2 - 8 1,8% Acinetobacter hemolyticus 3 4 - - 7 1,6% Acinetobacter johnsonii 1 3 - 2 6 1,3% Acinetobacter soli 3 2 - - 5 1,1% Acinetobacter guillouiae 1 3 - 1 5 1,1% Acinetobacter noscomialis 1 3 1 - 5 1,1% Acinetobacter towneri 1 2 - - 3 0,7% Acinetobacter schindleri 1 - 1 1 3 0,7% Acinetobacter variabilis 2 - - - 2 0,4% Acinetobacter venetianus 1 1 - - 2 0,4% Acinetobacter dispersus - 1 - 1 2 0,4% Acinetobacter parvus 1 - - 1 0,2% Acinetobacter kookii - 1 - - 1 0,2% Acinetobacter modestus 1 - - - 1 0,2% Acinetobacter gyllenbergii - 1 - - 1 0,2% Acinetobacter beijerinckii 1 - - - 1 0,2% Acinetobacter indicus 1 - - - 1 0,2% Acinetobacter seifertii 1 - - - 1 0,2% Total non-A.baumannii 213 155 43 36 447 Acinetobacter baumannii 181 387 374 9 951 Legend: The percentage was calculated as the proportion of a given species in the total number of infections of that type. Fisher's exact test revealed the following associations for bacterial species and infection types. Acinetobacter bereziniae was significantly associated with genitourinary tract infections and invasive infections (p<0.05). Acinetobacter junii and Acinetobacter pittii were significantly associated with genitourinary tract infections and SSTIs (p<0.05). Acinetobacter ursingii was significantly associated with genitourinary tract infections and invasive infections (p0.05) across all tested infection types. Among all the isolated strains, 50 (11.1%) were nonsusceptible to ampicillin/sulbactam, 4 (0.9%) to imipenem, 7 (1.6%) to meropenem, 11 (2.5%) to amikacin, 13 (2.9%) to gentamycin, 6 (1.3%) tobramycin, 26 to trimethoprim/sulfamethoxazole (5.8%) and 7 (1.6) to colistin (Table 4). Almost all the isolated strains (98.4%) were nonsusceptible to ciprofloxacin (19 were resistant, and 421 were characterized by intermediate susceptibility). Table 4. Number of strains nonsusceptible to selected antimicrobials among different types of infections. Infection type Tested antimicrobials and number of nonsusceptible strains AMP /SUL N (%) IMI N (%) MEM N (%) CIP N (%) AK N (%) GEN N (%) TOB N (%) COL N (%) SXT N (%) Genitourinary tract 33 (7.4%) 1 (0.2%) 2 (0.4%) 212 (47.4%) 7 (1.6%) 3 (0.7%) 3 (0.7%) 6 (1.3%) 9 (2%) SSTI 11 (2.5%) 1 (0.2%) 2 (0.4%) 150 (33.6%) 2 (0.4%) 5 (1.1%) 2 (0.4%) 1 (0.2%) 9 (2%) Invasive infections 3 (0.7%) 2 (0.4%) 2 (0.4%) 42 (9.4%) - 1 (0.2%) - - 2 (0.4%) Others 3 (0.7%) - 1 (0.2%) 36 (8.1%) 2 (0.4%) 4 (0.9%) 1 (0.2%) - 6 (1.3%) Total 50 (11.1%) 4 (0.9%) 7 (1.6%) 440 (98.4%) 11 (2.5%) 13 (2.9%) 6 (1.3%) 7 (1.6%) 26 (5.8%) Legend: The percentage represents the proportion of nonsusceptible strains for antimicrobial agents relative to the total number of strains isolated from infections of that type. AMP/SUL—ampililin/sulbactam; IMI—imipenem; MEM—meropenem; CIP—ciprofloxacin; AK—amikacin; GEN—gentamicin; TOB—tobramycin; SXT—trimethoprim/sulfamethoxazole; COL—colistin. The nonsusceptibility of non-AB strains during the studied years is presented in Figure 3. Across all years, the highest rates of nonsusceptibility were observed for ciprofloxacin, ampicillin-sulbactam, and trimethoprim/sulfamethoxazole. The analysis revealed no statistically significant differences in resistance to any of the tested antibiotics (ampicillin/sulbactam; imipenem; meropenem; ciprofloxacin; amikacin; gentamicin; tobramycin; trimethoprim/sulfamethoxazole; colistin) from 2021–2023 (p>0.05 for all tests). These findings suggest that resistance patterns were stable during the study period. Five non-AB species accounted for nearly 77% of all the isolated strains. Table 5 presents the nonsusceptibility patterns of strains isolated in quantities exceeding 20 over a three-year period. Across all the species, high nonsusceptibility to ciprofloxacin was observed (89.2% for A. lwoffii and 100% for A. pittii or A. junii ). Additionally, among A. bereziniae strains, relatively high percentages were nonsusceptible to carbapenems (9.1% for imipenem, 13.6% for meropenem), aminoglycosides (13.6% for amikacin, 22.7% for gentamycin), and trimethoprim/sulfamethoxazole (31.8%). Resistance to colistin was noted in A. ursingii and A. pittii strains. Table 5. A detailed characterization of the most frequently isolated species (n>20). Genus N 100% Tested antimicrobials and number of nonsusceptible strains AMP/SUL N (%) IMI N (%) MEM N (%) CIP N (%) AK N (%) GEN N (%) TOB N (%) COL N (%) SXT N (%) Acinetobacter ursingii (n=135) 18 (13.3%) 2 (1.5%) 3 (2.2%) 133 (98.5%) 4 (3.0%) 2 (1.5%) 2 (1.5%) 3 (2.2%) 12 (8.9%) Acinetobacter pittii (n=92) 7 (7.6%) 0 1 (1.1%) 92 (100%) 0 1 (1.1%) 0 3 (3.3%) 0 Acinetobacter junii (n=58) 8 (13.8%) 0 0 58 (100%) 0 0 0 0 1 (1.7%) Acinetobacter lwoffi (n=37) 1 (2.7%) 0 0 33 (89.2%) 0 0 0 0 3 (8.1%) Acinetobacter bereziniae (n=22) 1 (4.5%) 2 (9.1%) 3 (13.6%) 22 (100%) 3 (13.6%) 5 (22.7%) 1 (4.5%) 0 7 (31.8%) Legend: The percentage of resistant strains in relation to all strains of a given species. AMP/SUL—ampililin/sulbactam; IMI—imipenem; MEM—meropenem; CIP—ciprofloxacin; AK—amikacin; GEN—gentamicin; TOB—tobramycin; SXT—trimethoprim/sulfamethoxazole; COL—colistin. All the strains resistant to colistin were isolated from male outpatients. Five of them originated from urinary tract infections from one outpatient clinic, while the remaining two were from a urinary tract infection and a wound infection from two other outpatient clinics. These strains were susceptible to imipenem and trimethoprim/sulfamethoxazole. Detailed information on colistin-resistant strains is summarized in Table 6. Table 6. Detailed data on colistin-resistant strains. R-resistant, S-susceptible. Outpatient clinic Age Gender Infection type Strain AMP/ SUL IMI MEM CIP AK GEN TOB SXT 1 57 M Urinary tract Acinetobacter ursingii S S S R S S S S 1 37 M Urinary tract Acinetobacter ursingii S S S R S S S S 1 81 M Urinary tract Acinetobacter ursingii S S R R R R R S 1 75 M Urinary tract Acinetobacter pittii S S S R S S S S 1 49 M Urinary tract Acinetobacter lactucae S S S R R S S S 2 59 M Wound Acinetobacter noscomialis S S S S S S S S 3 70 M Urinary tract Acinetobacter pittii S S S R S S S S Discussion Infections caused by Acinetobacter spp. have been increasing in prevalence in recent years and are emerging as a global public health concern due to increasing antibiotic resistance in healthcare settings ( 7 , 8 , 10 , 19 , 38 , 43 ). Epidemiological data from the ECDC 2022–23 point prevalence study indicated that in Europe, AB is primarily responsible for respiratory and bloodstream infections (European Centre for Disease Prevention and Control ( 44 ). The WHO has listed carbapenem-resistant AB as a critical-priority pathogen among those bacteria that require the research and development of new drugs ( 29 ). According to ECDC data, the percentages of carbapenem-resistant Acinetobacter spp. varied widely within the European region in 2023, from less than 5% to equal to or greater than 50% in 18 countries, mostly in southern and eastern Europe, including Poland ( 45 ). Pandrug-resistant strains are being identified more frequently among AB strains ( 46 ). In Poland, there has been a problem with extensively drug-resistant AB strains for many years, especially in intensive care unit (ICU) departments ( 47 , 48 ). The results of our current study indicate that although AB is the predominant species, accounting for the majority (63.1%) of isolates from infections between 2021 and 2023, the significant role of non-AB species in clinical infections should also be emphasized. Non-AB infections accounted for an average of 36.9%, with the highest proportion recorded in 2022 at 42.9%. Non-AB species should not be overlooked, particularly in genitourinary infections and skin and soft tissue infections. Additionally, in less common infections, such as ear and eye infections, the majority of strains are non-ABs rather than ABs. Although the frequency of isolation of AB strains was greater among those with SSTIs (71%) and invasive infections (90%), non-AB strains dominated among those with genital tract infections (87%). Acinetobacter species, particularly non-AB strains, are commonly isolated from genital tract infections due to several factors. These bacteria are opportunistic pathogens that thrive in diverse environments, including the urinary and genital tracts, especially in immunocompromised individuals or those with indwelling devices such as catheters. The ability of these bacteria to survive in the human body and adapt to various conditions, including those in hospital settings, contributes to their frequent isolation in infections. In addition, some species, such as A. pittii and A. nosocomialis , have been found in urinary tract infections ( 38 ). The results suggest that a greater proportion of non-AB strains (73.4%) were isolated from outpatients than from hospital patients (26.6%), indicating that these strains may be more commonly associated with outpatient settings. However, with respect to the detailed distribution of particular strains, A. bereziniae , A. proteolyticus, A. calcoaceticus and A. lwoffii were isolated more frequently from hospitalized patients (63.6%, 62.5%, 60% and 45.9%, respectively) and were connected (together with A. pittii ) with invasive infections. Some reports indicate that A. pittii and other species of Abc are isolated most often from hospitalized patients and may be transmitted horizontally ( 39 ). A. pittii has increasingly been associated with various types of hospital-acquired infections, including bloodstream infections, ventilator-associated pneumonia, and wound infections ( 18 – 20 , 49 ). Similar to other studies, our results have shown that A. pittii is increasingly recognized in bloodstream infections and accounts for approximately 30.2% of non-AB BSIs in clinical settings ( 49 ). A. berezianiae strains that are resistant to carbapenems are being isolated from hospitalized patients more frequently ( 34 ). Studies by Guedes-Stehling et al. demonstrated that A. bereziniae can be transferred between the natural environment, animals and humans and is a potential One Health bacteria that require close surveillance ( 50 ). The most commonly isolated species in our study, particularly from outpatient samples, were A. ursingii , A. junii , and A. pittii , with prevalence rates of 86.6%, 84.5%, and 70.6%, respectively. Non-AB strains are frequently isolated from outpatients due to several factors. These species are often part of the normal microbiota in the environment and can cause infections in individuals who are not critically ill or hospitalized. They may also be more prevalent in outpatient settings, where the population typically consists of patients with less severe conditions who are not exposed to the intense antibiotic pressures found in hospitals. Additionally, non-AB species may have a lower degree of resistance than AB, allowing them to persist more easily in outpatient environments​. Importantly, more than one-third (n = 171, 38.3%) of the non-AB strains were isolated from pure cultures. While the pathogenicity of these species remains under investigation, it is possible that these emerging environmental species contribute to infectious processes, particularly in immunocompromised patients, individuals undergoing invasive procedures, or those receiving broad-spectrum antibiotic therapy. The Acinetobacter genus, known for its intrinsic resistance to desiccation, metabolic adaptability, and role as a reservoir of resistance genes, necessitates isolation, precise species identification and typing for effective epidemiological control in hospitals ( 38 , 43 ). However, in the case of SSTI infections, particularly when chronic wounds are infected, bacteria often form polymicrobial biofilms. In our study, more than one microorganism was isolated from almost two-thirds of the studied samples. This study revealed that non-AB strains are often associated with polymicrobial infections, particularly skin and soft tissue infections (SSTIs), where they frequently coexist with Gram-positive cocci such as Enterococcus faecalis or Staphylococcus . The presence of numerous microorganisms in chronic wounds or diabetic ulcers can delay healing, as they not only directly damage tissue but also attract leukocytes and activate inflammatory cytokines and proteases ( 51 ). Microbes within biofilms are highly adaptable to harsh conditions, enabling them to survive various treatments, including antibiotics ( 52 ). The polymicrobial etiology also included infections of the genital tract; in addition to Acinetobacter strains, E. faecalis strains are commonly isolated. The vaginal microbiome is continuously changing, especially as bacteria from the gut microbiome may travel down to the female urogenital tract. Opportunistic pathogens can form biofilms that can help them circumvent the potency of antibiotics while simultaneously exerting virulence factors that degrade vaginal epithelial cells in patients ( 53 ). Non-AB strains can constitute a significant part of the biofilm formed in genital tract infections and contribute to bacterial vaginosis or aerobic vaginitis. A statistically significant relationship was found between the presence of AB infections and primary infection types: AB infections were predominantly associated with invasive infections, whereas non-AB species were more frequently observed in the genitourinary tract category. These results suggest a clinically relevant difference in the distribution of infection types between AB and non-AB. AB infections were more strongly associated with invasive and soft tissue infections, whereas non-AB infections were more prevalent in genitourinary infections. Further investigations are warranted to understand the clinical implications of these findings. The majority of the isolated strains were susceptible to all the tested antimicrobials. Among the 447 strains analyzed, only a small number of isolates exhibited resistance to critical antibiotics, such as imipenem (0.9%) and meropenem (1.6%), which are important for treating severe infections. The proportion of strains resistant to ampicillin-sulbactam was greater among strains isolated from genitourinary tract infections, which may be related to the fact that this agent is commonly used to treat such infections. Notably, 98.4% of the isolated strains were not susceptible to ciprofloxacin, raising questions about the effectiveness of fluoroquinolones in clinical settings. Acinetobacter species often possess efflux pumps, which actively expel ciprofloxacin and other antibiotics from bacterial cells, reducing the concentration of the drug inside the cell and decreasing its effectiveness ( 54 ). In a similar study in Germany involving specimens collected between 2010 and 2019, 25% of the isolates were resistant to ciprofloxacin ( 55 ). The results from the 2020 Spanish nationwide study revealed that 60% of Acinetobacter strains were resistant ( 56 ). Fluoroquinolones have historically shown good activity against Acinetobacter spp., but over the last 20 years, there has been a large increase in fluoroquinolone resistance and multidrug resistance ( 57 ). The high resistance to fluoroquinolones in our study may have resulted from the high consumption of this group of antibiotics in Europe. In Poland, the use of fluoroquinolones decreased during the pandemic but has been increasing again since 2022 ( 58 ). The large proportion of ciprofloxacin-nonsusceptible strains in our study may also be connected with the chosen methodology. We included resistant strains and those with intermediate susceptibility among the nonsusceptible strains, which resulted in a high percentage of nonsusceptible strains (98.4%). Only 19 (4.3%) strains were resistant to ciprofloxacin, whereas 421 (94.1%) strains exhibited intermediate susceptibility. Many publications address the problem of the global spread of AB strains resistant to carbapenems and producing acquired carbapenemases ( 59 , 60 ). Other Acinetobacter species have been less well studied, although there are numerous reports of isolates of other Acinetobacter spp. producing various carbapenemases, including metallo-beta-lactamases ( 18 , 23 , 24 , 34 , 39 , 43 ). Although in our study, only a small number of strains exhibited resistance to carbapenems (0.9% to imipenem, 1.6% to meropenem) or colistin (1.6%), monitoring resistance to these last-resort antibiotics is crucial. The emergence of resistance to those antimicrobials may significantly limit treatment options for severe or life-threatening infections. Sheck et al. demonstrated that colistin resistance was more than three times greater in non-AB strains than in A. baumannii strains (3.0% vs. 0.8%), with the majority of colistin-resistant isolates identified as A. bereziniae ( 39 ). The latter species was also more resistant to sulbactam, aminoglycosides, trimethoprim–sulfamethoxazole, and tigecycline than other non-AB species ( 39 ). This result is consistent with our findings, with A. bereziniae showing the highest resistance to carbapenems, all aminoglycosides, and trimethoprim–sulfamethoxazole. Only the resistance to ampicillin/sulbactam was greater among A. ursingii strains. Opazo-Capurro's results also indicate the importance of monitoring A. bereziniae for resistance and its potential to cause difficult-to-treat infections ( 34 ). Our colistin-resistant strains were mainly A. ursingii and A. pittii. Sykes described a hypervirulent hospital strain resistant to colistin belonging to the species A. courvalinii ( 61 ). Pandrug-resistant A. pittii has been isolated from a patient with pneumonia in a Chinese hospital ( 36 ). In Latin America, Acinetobacter spp. resistance to imipenem and meropenem varies from 8–89% ( 62 , 63 ). Conclusions Our study indicated that even if A. baumannii accounts for 63.1% of isolates from infections between 2021 and 2023, non- A. baumannii species also play a significant role, particularly in genitourinary and skin infections. Various species, including A. pittii , have been increasingly associated with hospital-acquired infections, highlighting the need for vigilant monitoring of these pathogens. This study revealed a high resistance rate to ciprofloxacin among isolated strains. Although only a small percentage of strains are resistant to carbapenems or colistin, the emergence of such resistance could severely limit treatment options for critical infections. Early detection and surveillance of resistance patterns are essential to prevent the widespread dissemination of resistant strains. Moreover, ongoing monitoring can inform public health measures and contribute to the development of new therapeutic options. This study also emphasizes the importance of distinguishing between A. baumannii and non- A. baumannii species in clinical practice to inform treatment strategies effectively and mitigate the risk of antibiotic resistance spread in healthcare environments. Limitations of the study The study did not categorize Acinetobacter baumannii strains on the basis of whether they were isolated from hospitalized patients or outpatients. This makes it difficult to draw clear conclusions about the prevalence and resistance patterns specific to these two patient groups, which may have different infection risks and exposure to antibiotics​ The authors were also unable to examine the detailed mechanisms of resistance in all the isolated strains because of the observational nature of the study. While resistance patterns have been observed, the underlying molecular mechanisms have not been explored. Understanding these mechanisms would provide deeper insights into how resistance develops and how it can be mitigated​ Declarations Acknowledgments Funding: This research was funded by the National Science Centre, grant number 2020/39/O/NZ7/00145. Institutional Review Board Statement: The study was conducted in accordance with the Declaration of Helsinki and approved by the Bioethics Committee of Jagiellonian University (opinion number KBET 1072.6120.274.2021). 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Antimicrobial resistance surveillance in Europe 2023 - 2021 data. 2023 [cited 2024 Dec 13]; Available from: https://www.ecdc.europa.eu/en/publications-data/antimicrobial-resistance-surveillance-europe-2023-2021-data Spiliopoulou A, Giannopoulou I, Assimakopoulos SF, Jelastopulu E, Bartzavali C, Marangos M, et al. Laboratory Surveillance of Acinetobacter spp. Bloodstream Infections in a Tertiary University Hospital during a 9-Year Period. Tropical Medicine and Infectious Disease 2023, Vol 8, Page 503 [Internet]. 2023 Nov 19 [cited 2024 Dec 13];8(11):503. Available from: https://www.mdpi.com/2414-6366/8/11/503/htm Chmielarczyk A, Pilarczyk-Zurek M, Kamińska W, Pobiega M, Romaniszyn D, Ziółkowski G, et al. Molecular Epidemiology and Drug Resistance of Acinetobacter baumannii Isolated from Hospitals in Southern Poland: ICU as a Risk Factor for XDR Strains. https://home.liebertpub.com/mdr [Internet]. 2016 Jun 6 [cited 2024 Dec 13];22(4):328–35. Available from: https://www.liebertpub.com/doi/10.1089/mdr.2015.0224 Kasperski T, Romaniszyn D, Jachowicz-Matczak E, Pomorska-Wesołowska M, Wójkowska-Mach J, Chmielarczyk A. Extensive Drug Resistance of Strong Biofilm-Producing Acinetobacter baumannii Strains Isolated from Infections and Colonization Hospitalized Patients in Southern Poland. Pathogens 2023, Vol 12, Page 975 [Internet]. 2023 Jul 26 [cited 2024 Dec 13];12(8):975. Available from: https://www.mdpi.com/2076-0817/12/8/975/htm Bello-López E, Escobedo-Muñoz AS, Guerrero G, Cruz-Córdova A, Garza-González E, Hernández-Castro R, et al. Acinetobacter pittii: the emergence of a hospital-acquired pathogen analyzed from the genomic perspective. Front Microbiol. 2024 Jun 26;15:1412775. Stehling EG, Sellera FP, de Almeida OGG, Gonzalez IHL, Ramos PL, da Rosa-Garzon NG, et al. Genomic features and comparative analysis of a multidrug-resistant Acinetobacter bereziniae strain infecting an animal: a novel emerging one health pathogen? World J Microbiol Biotechnol [Internet]. 2024 Feb 1 [cited 2024 Dec 13];40(2):1–10. Available from: https://link.springer.com/article/10.1007/s11274-023-03867-y Mudge EJ. Recent accomplishments in wound healing. Int Wound J [Internet]. 2015 Feb 1 [cited 2024 Dec 13];12(1):4–9. Available from: https://pubmed.ncbi.nlm.nih.gov/24618286/ Öien RF, Forssell HW. Ulcer healing time and antibiotic treatment before and after the introduction of the Registry of Ulcer Treatment: an improvement project in a national quality registry in Sweden. BMJ Open [Internet]. 2013 Aug 1 [cited 2024 Dec 13];3(8):e003091. Available from: https://bmjopen.bmj.com/content/3/8/e003091 Núño K, Jensen AS, O’Connor G, Houston TJ, Dikici E, Zingg JM, et al. Insights into Women’s health: Exploring the vaginal microbiome, quorum sensing dynamics, and therapeutic potential of quorum sensing quenchers. Mol Aspects Med [Internet]. 2024 Dec 1 [cited 2024 Dec 13];100. Available from: https://pubmed.ncbi.nlm.nih.gov/39255544/ Poole K. Efflux-mediated antimicrobial resistance. J Antimicrob Chemother [Internet]. 2005 Jul [cited 2024 Dec 11];56(1):20–51. Available from: https://pubmed.ncbi.nlm.nih.gov/15914491/ Wohlfarth E, Kresken M, Higgins PG, Stefanik D, Wille J, Hafner D, et al. The evolution of carbapenem resistance determinants and major epidemiological lineages among carbapenem-resistant Acinetobacter baumannii isolates in Germany, 2010-2019. Int J Antimicrob Agents [Internet]. 2022 Nov 1 [cited 2024 Dec 11];60(5–6). Available from: https://pubmed.ncbi.nlm.nih.gov/36375774/ Lasarte-Monterrubio C, Guijarro-Sánchez P, Alonso-Garcia I, Outeda M, Maceiras R, González-Pinto L, et al. Epidemiology, resistance genomics and susceptibility of Acinetobacter species: results from the 2020 Spanish nationwide surveillance study. Euro Surveill [Internet]. 2024 Apr 11 [cited 2024 Dec 11];29(15). Available from: https://pubmed.ncbi.nlm.nih.gov/38606569/ Dalhoff A. Global fluoroquinolone resistance epidemiology and implictions for clinical use. Interdiscip Perspect Infect Dis [Internet]. 2012 [cited 2024 Dec 13];2012. Available from: https://pubmed.ncbi.nlm.nih.gov/23097666/ Monitorowanie zużycia antybiotyków w lecznictwie otwartym za rok 2022 [Internet]. [cited 2025 Jan 12]. Available from: https://antybiotyki.edu.pl/wp-content/uploads/2024/04/Raport-NPZ-4.1-Konsumpcja-otwarte_2023_12_28.pdf Hamidian M, Nigro SJ. Emergence, molecular mechanisms and global spread of carbapenem-resistant Acinetobacter baumannii. Microb Genom [Internet]. 2019 [cited 2024 Dec 13];5(10):e000306. Available from: https://pmc.ncbi.nlm.nih.gov/articles/PMC6861865/ Ghahramani A, Naghadian Moghaddam MM, Kianparsa J, Ahmadi MH. Overall status of carbapenem resistance among clinical isolates of Acinetobacter baumannii: a systematic review and meta-analysis. J Antimicrob Chemother [Internet]. 2024 Dec 2 [cited 2024 Dec 13];79(12):3264–80. Available from: https://pubmed.ncbi.nlm.nih.gov/39392464/ Sykes EME, Mateo-Estrada V, Muzaleva A, Zhanel G, Dettman J, Chapados J, et al. Characterization of a colistin resistant, hypervirulent hospital isolate of Acinetobacter courvalinii from Canada. Eur J Clin Microbiol Infect Dis [Internet]. 2024 Oct 1 [cited 2024 Dec 13];43(10):1939–49. Available from: https://pubmed.ncbi.nlm.nih.gov/39073669/ Satán C, Satyanarayana S, Shringarpure K, Mendoza-Ticona A, Palanivel C, Jaramillo K, et al. Epidemiology of antimicrobial resistance in bacteria isolated from inpatient and outpatient samples, Ecuador, 2018. Rev Panam Salud Publica;47, 2023 Resistencia a los Antimicrobianos [Internet]. 2023 [cited 2024 Dec 11];47. Available from: https://iris.paho.org/handle/10665.2/57313 Magnitud y tendencias de la resistencia a los antimicrobianos en Latinoamérica. RELAVRA 2014, 2015, 2016. Informe resumido - OPS/OMS | Organización Panamericana de la Salud [Internet]. [cited 2024 Dec 18]. Available from: https://www.paho.org/es/documentos/magnitud-tendencias-resistencia-antimicrobianos-latinoamerica-relavra-2014-2015-2016 Additional Declarations No competing interests reported. Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-5821427","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":401921544,"identity":"1da0f6c5-36aa-4579-8f16-d61831fb7747","order_by":0,"name":"Kasperski Tomasz","email":"","orcid":"","institution":"Doctoral School of Medical and Health Sciences, Jagiellonian University Medical College","correspondingAuthor":false,"prefix":"","firstName":"Kasperski","middleName":"","lastName":"Tomasz","suffix":""},{"id":401921545,"identity":"c895ed31-7ac2-4877-aae8-b42776e58ea9","order_by":1,"name":"Pobiega Monika","email":"","orcid":"","institution":"Jagiellonian University Medical College, Faculty of Medicine, Department of Microbiology","correspondingAuthor":false,"prefix":"","firstName":"Pobiega","middleName":"","lastName":"Monika","suffix":""},{"id":401921547,"identity":"9dc5445a-2777-4d16-96c0-46a64c6c264e","order_by":2,"name":"Pomorska-Wesołowska Monika","email":"","orcid":"","institution":"Department of Microbiology, Analytical and Microbiological Laboratory of Ruda Slaska, KORLAB NZOZ","correspondingAuthor":false,"prefix":"","firstName":"Pomorska-Wesołowska","middleName":"","lastName":"Monika","suffix":""},{"id":401921548,"identity":"bab59031-3577-4036-81de-f7d1b2cac49c","order_by":3,"name":"Papuga Wiktoria","email":"","orcid":"","institution":"Department of Microbiology, Analytical and Microbiological Laboratory of Ruda Slaska, KORLAB NZOZ","correspondingAuthor":false,"prefix":"","firstName":"Papuga","middleName":"","lastName":"Wiktoria","suffix":""},{"id":401921551,"identity":"bb98c7ba-9582-4393-a8b2-b6da9aba77f8","order_by":4,"name":"Chmielarczyk Agnieszka","email":"data:image/png;base64,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","orcid":"","institution":"Jagiellonian University Medical College, Faculty of Medicine, Department of Microbiology","correspondingAuthor":true,"prefix":"","firstName":"Chmielarczyk","middleName":"","lastName":"Agnieszka","suffix":""}],"badges":[],"createdAt":"2025-01-13 16:13:15","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-5821427/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-5821427/v1","draftVersion":[],"editorialEvents":[],"editorialNote":"","failedWorkflow":false,"files":[{"id":73869554,"identity":"40d48bef-3dd5-4358-99f3-5999cb6aa332","added_by":"auto","created_at":"2025-01-15 12:09:14","extension":"png","order_by":1,"title":"Figure 1","display":"","copyAsset":false,"role":"figure","size":749453,"visible":true,"origin":"","legend":"\u003cp\u003eThe locations of outpatient departments and hospitals in southern Poland.\u003c/p\u003e","description":"","filename":"Figure1.png","url":"https://assets-eu.researchsquare.com/files/rs-5821427/v1/c4339640fd2042053593ae66.png"},{"id":73869257,"identity":"1585529f-20e2-4bb7-a388-7e5a06fff655","added_by":"auto","created_at":"2025-01-15 12:09:03","extension":"png","order_by":2,"title":"Figure 2","display":"","copyAsset":false,"role":"figure","size":39349,"visible":true,"origin":"","legend":"\u003cp\u003eRelative frequency of \u003cem\u003eAcinetobacter baumannii\u003c/em\u003e and non-\u003cem\u003eAcinetobacter baumannii\u003c/em\u003e infections according to the type of infection.\u003c/p\u003e","description":"","filename":"Figure2.png","url":"https://assets-eu.researchsquare.com/files/rs-5821427/v1/a107563a40d1425bb8e992a3.png"},{"id":73869548,"identity":"124073a2-dd2e-407a-802a-5aa661c6f30c","added_by":"auto","created_at":"2025-01-15 12:09:13","extension":"png","order_by":3,"title":"Figure 3","display":"","copyAsset":false,"role":"figure","size":38053,"visible":true,"origin":"","legend":"\u003cp\u003eThe percentage of nonsusceptible non-AB isolates to specific antibiotics. Legend: AMP/SUL—ampililin/sulbactam; IMI—imipenem; MEM—meropenem; CIP—ciprofloxacin; AK—amikacin; GEN—gentamicin; TOB—tobramycin; SXT—trimethoprim/sulfamethoxazole; COL—colistin.\u003c/p\u003e","description":"","filename":"Figure3.png","url":"https://assets-eu.researchsquare.com/files/rs-5821427/v1/e6d693d94ed304a0fc0610da.png"},{"id":79867218,"identity":"94ece681-220c-47d5-ba65-ae4332f3c0d3","added_by":"auto","created_at":"2025-04-03 19:31:47","extension":"pdf","order_by":0,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":3511621,"visible":true,"origin":"","legend":"","description":"","filename":"manuscript.pdf","url":"https://assets-eu.researchsquare.com/files/rs-5821427/v1/24c81bf6-d030-498e-80f8-7f994799eced.pdf"}],"financialInterests":"No competing interests reported.","formattedTitle":"Distribution and antimicrobial resistance of Acinetobacter spp. isolated from different types of infections from hospitalized patients and outpatients in Poland","fulltext":[{"header":"Introduction","content":"\u003cp\u003e \u003cem\u003eAcinetobacter\u003c/em\u003e, a genus consisting of biochemically and physiologically versatile Gram-negative coccobacilli that are distributed in nature, may play an important role in opportunistic human infections. This genus is characterized as aerobic, nonfermenting, nonfastidious, immobile, catalase-positive, and oxidase-negative bacteria (\u003cspan citationid=\"CR1\" class=\"CitationRef\"\u003e1\u003c/span\u003e). The taxonomy of the genus currently consists of 85 distinct validly named species (\u003cspan citationid=\"CR2\" class=\"CitationRef\"\u003e2\u003c/span\u003e, \u003cspan citationid=\"CR3\" class=\"CitationRef\"\u003e3\u003c/span\u003e). On the basis of the genomic analyses, new individual species are still being distinguished, characterized by genomic distinctness and monophyly. The last species to be fully validated are \u003cem\u003eAcinetobacter suaedae\u003c/em\u003e and \u003cem\u003eAcinetobacter oleivorans\u003c/em\u003e (\u003cspan citationid=\"CR4\" class=\"CitationRef\"\u003e4\u003c/span\u003e, \u003cspan citationid=\"CR5\" class=\"CitationRef\"\u003e5\u003c/span\u003e).\u003c/p\u003e \u003cp\u003eAmong this genus, \u003cem\u003eA. baumannii\u003c/em\u003e (AB) is the most frequently isolated nosocomial pathogen and is considered the most clinically relevant, followed by other members of the \u003cem\u003eAcinetobacter baumannii\u003c/em\u003e-\u003cem\u003ecalcoaceticus\u003c/em\u003e complex (Abc) (\u003cem\u003eA. calcaoaceticus\u003c/em\u003e, \u003cem\u003eA. pitti\u003c/em\u003e, \u003cem\u003eA. nosocomialis\u003c/em\u003e, \u003cem\u003eA. seifertti\u003c/em\u003e, \u003cem\u003eA. dijkshoorniaem\u003c/em\u003e) (\u003cspan citationid=\"CR6\" class=\"CitationRef\"\u003e6\u003c/span\u003e, \u003cspan citationid=\"CR7\" class=\"CitationRef\"\u003e7\u003c/span\u003e). There are also reports of less common but still important and serious infections caused by \u003cem\u003eAcinetobacter ursingii\u003c/em\u003e, \u003cem\u003eAcinetobacter haemolyticus\u003c/em\u003e, \u003cem\u003eAcinetobacter lwoffii\u003c/em\u003e, \u003cem\u003eAcinetobacter parvus\u003c/em\u003e, and \u003cem\u003eAcinetobacter junii\u003c/em\u003e (\u003cspan additionalcitationids=\"CR9 CR10 CR11 CR12\" citationid=\"CR8\" class=\"CitationRef\"\u003e8\u003c/span\u003e\u0026ndash;\u003cspan citationid=\"CR13\" class=\"CitationRef\"\u003e13\u003c/span\u003e).\u003c/p\u003e \u003cp\u003eHuman infections caused by \u003cem\u003eA. lwoffii\u003c/em\u003e, \u003cem\u003eA. courvalinii\u003c/em\u003e, \u003cem\u003eA. johnsonii\u003c/em\u003e, and \u003cem\u003eA. bereziniae\u003c/em\u003e have been recognized recently by using new diagnostic methods (\u003cspan additionalcitationids=\"CR15\" citationid=\"CR14\" class=\"CitationRef\"\u003e14\u003c/span\u003e\u0026ndash;\u003cspan citationid=\"CR16\" class=\"CitationRef\"\u003e16\u003c/span\u003e). \u003cem\u003eAcinetobacter\u003c/em\u003e spp. are also involved in cases of coinfection with SARS-CoV-2 (\u003cspan citationid=\"CR15\" class=\"CitationRef\"\u003e15\u003c/span\u003e, \u003cspan citationid=\"CR16\" class=\"CitationRef\"\u003e16\u003c/span\u003e)\u003c/p\u003e \u003cp\u003e \u003cem\u003eA. pittii\u003c/em\u003e is associated with hospital-acquired infections, such as bloodstream infections, ventilator-associated pneumonia, and wound infections (\u003cspan citationid=\"CR18\" class=\"CitationRef\"\u003e18\u003c/span\u003e, \u003cspan citationid=\"CR19\" class=\"CitationRef\"\u003e19\u003c/span\u003e). There are reports from France and Germany showing that \u003cem\u003eA. pittii\u003c/em\u003e is the most common \u003cem\u003eAcinetobacter\u003c/em\u003e species isolated (\u003cspan citationid=\"CR20\" class=\"CitationRef\"\u003e20\u003c/span\u003e, \u003cspan citationid=\"CR21\" class=\"CitationRef\"\u003e21\u003c/span\u003e). \u003cem\u003eA. ursingii\u003c/em\u003e has been reported as a cause of infections (including bacteremia) in the Netherlands, Japan and the pediatric ward in Argentina (\u003cspan additionalcitationids=\"CR23\" citationid=\"CR22\" class=\"CitationRef\"\u003e22\u003c/span\u003e\u0026ndash;\u003cspan citationid=\"CR24\" class=\"CitationRef\"\u003e24\u003c/span\u003e). \u003cem\u003eA. junii\u003c/em\u003e was reported as a cause of bacteremia, ocular infection and an outbreak in the neonatal ward (\u003cspan additionalcitationids=\"CR26\" citationid=\"CR25\" class=\"CitationRef\"\u003e25\u003c/span\u003e\u0026ndash;\u003cspan citationid=\"CR27\" class=\"CitationRef\"\u003e27\u003c/span\u003e)\u003c/p\u003e \u003cp\u003eMultidrug-resistant (MDR) bacteria currently cause over 700,000 deaths each year, and it is estimated that this number could rise to 10\u0026nbsp;million by 2050 (\u003cspan citationid=\"CR28\" class=\"CitationRef\"\u003e28\u003c/span\u003e). The World Health Organization (WHO) highlights AB as one of the top antibiotic-resistant \"priority pathogens\", for which the development of new antibiotics is urgently needed (\u003cspan citationid=\"CR29\" class=\"CitationRef\"\u003e29\u003c/span\u003e). This phenomenon is associated with a high mortality rate of \u003cem\u003eAcinetobacter\u003c/em\u003e infection, ranging from 45 to 70% (\u003cspan citationid=\"CR30\" class=\"CitationRef\"\u003e30\u003c/span\u003e, \u003cspan citationid=\"CR31\" class=\"CitationRef\"\u003e31\u003c/span\u003e), and easy transfer of antibiotic resistance genes among \u003cem\u003eAcinetobacter\u003c/em\u003e species, which leads to the emergence of multidrug-resistant pathogens, resulting in the use of few antimicrobial agents (\u003cspan citationid=\"CR32\" class=\"CitationRef\"\u003e32\u003c/span\u003e, \u003cspan citationid=\"CR33\" class=\"CitationRef\"\u003e33\u003c/span\u003e). Moreover, \u003cem\u003eAcinetobacter\u003c/em\u003e spp. have intrinsic antimicrobial resistance mechanisms that are expressed constitutively or in response to antibiotics in the environment. The greatest concern is carbapenem resistance, as those antimicrobials are considered last-resort in the treatment of infections caused by resistant strains. Carbapenem resistance in non-\u003cem\u003eA. baumannii\u003c/em\u003e (non-AB) species is driven by a variety of oxacillinases, as in \u003cem\u003eA. baumannii\u003c/em\u003e. However, genes encoding metallo-beta-lactamases such as NDM and IMP have also been identified in other \u003cem\u003eAcinetobacter\u003c/em\u003e species, including \u003cem\u003eA. bezeriniae\u003c/em\u003e, \u003cem\u003eA. ursingii\u003c/em\u003e, \u003cem\u003eA. pittii\u003c/em\u003e, and \u003cem\u003eA. lwoffii\u003c/em\u003e, among others (\u003cspan citationid=\"CR24\" class=\"CitationRef\"\u003e24\u003c/span\u003e, \u003cspan citationid=\"CR34\" class=\"CitationRef\"\u003e34\u003c/span\u003e, \u003cspan citationid=\"CR35\" class=\"CitationRef\"\u003e35\u003c/span\u003e). Carbapenem resistance is often associated with resistance to other antibiotics. Pandrug-resistant strains have been found among \u003cem\u003eA. pittii\u003c/em\u003e strains (\u003cspan citationid=\"CR36\" class=\"CitationRef\"\u003e36\u003c/span\u003e). In addition to being drug resistant, \u003cem\u003eAcinetobacter\u003c/em\u003e is characterized by high virulence; AB is perceived as the most virulent one, followed by \u003cem\u003eA. calcoaceticus\u003c/em\u003e and \u003cem\u003eA. lwoffii\u003c/em\u003e (\u003cspan additionalcitationids=\"CR38\" citationid=\"CR37\" class=\"CitationRef\"\u003e37\u003c/span\u003e\u0026ndash;\u003cspan citationid=\"CR39\" class=\"CitationRef\"\u003e39\u003c/span\u003e).\u003c/p\u003e \u003cp\u003eIn addition to the growing concerns of carbapenem resistance in \u003cem\u003eAcinetobacter\u003c/em\u003e species, the increasing frequency of \u003cem\u003eAcinetobacter\u003c/em\u003e infections in hospital settings highlights the importance of surveillance and antibiotic stewardship. The resistance mechanisms of \u003cem\u003eAcinetobacter\u003c/em\u003e species, together with their ability to acquire further resistance through horizontal gene transfer, contribute to their persistence in healthcare environments. Given their ability to form biofilms and adapt to hostile environments, \u003cem\u003eAcinetobacter\u003c/em\u003e spp. are notorious for causing challenging infections in both hospital and community settings (\u003cspan citationid=\"CR40\" class=\"CitationRef\"\u003e40\u003c/span\u003e). It is essential to monitor the epidemiology, resistance profiles, and virulence of \u003cem\u003eAcinetobacter\u003c/em\u003e spp. to develop effective treatment strategies and prevent the further spread of multidrug-resistant strains.\u003c/p\u003e \u003cp\u003eThe aim of this study was to investigate the distribution and antibiotic resistance patterns of \u003cem\u003eAcinetobacter\u003c/em\u003e spp. strains isolated from various types of infections in both hospitalized patients and outpatients in southern Poland.\u003c/p\u003e"},{"header":"Materials and methods","content":"\u003cp\u003e\u003cstrong\u003e2.1 Patient population\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe bacterial strains were collected between January 2021 and December 2023 from all clinical materials during routine diagnosis from patients hospitalized at 13 hospitals and from 30 outpatient departments of Silesian Province (mainly Katowice, Sosnowiec, Ruda Śląska, Piekary Śląskie, Świętochłowice, Knur\u0026oacute;w, etc.) and Opolskie Province (Opole, Głuchołazy) in southern Poland. The locations of outpatient departments and hospitals are shown on the map of southern Poland (Figure 1). The data were collected and analyzed in cooperation with the KORLAB Laboratory in Ruda Śląska. All patients\u0026apos; data were anonymized before the analysis was conducted.\u003c/p\u003e\n\u003cp\u003eThe strains were selected according to the following criteria: (i) belonging to the Acinetobacter genus (infections caused by AB were analyzed for comparative purposes, but AB\u003cem\u003e\u0026nbsp;\u003c/em\u003ewas excluded from the detailed study), (ii) nonduplicate samples, and (iii) were isolated from different patients.\u003c/p\u003e\n\u003cp\u003eThe strains were collected in accordance with the consent of the Bioethics Committee of Jagiellonian University KBET 1072.6120.274.2021.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e2.2. Bacterial isolates\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eBacterial cultures were grown overnight on Columbia sheep blood agar (Becton Dickinson, Heidelberg, Germany) at 37\u0026deg;C. The isolates were identified via an automated MALDI-TOF Biotyper system (matrix-assisted laser desorption/ionization with a time-of-flight analyzer) with the mass spectral library MBT IVD LIBRARY \u0026nbsp; (Bruker, Billerica, Massachusetts, United States).\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e2.3. Antimicrobial susceptibility testing\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eAntibiotic susceptibility was determined on the basis of the results of an automated MIDITECH Analyzer v.12 system for ampicillin/sulbactam; imipenem; meropenem; amikacin; gentamicin; tobramycin ciprofloxacin; trimethoprim/sulfamethoxazole; and colistin. The results were interpreted using the clinical breakpoints defined in the latest EUCAST guidelines\u0026mdash;v.\u0026nbsp;14.0 (41). For ampicillin/sulbactam, the interpretation was made on the basis of Clinical and Laboratory Standards Institute (CLSI) guidelines (42). The MIC for colistin was confirmed using the microdilution method (MIC STRIPPED PLATES COL; Diagnostics, Slovakia), and the results were interpreted in line with the manufacturer\u0026rsquo;s instructions according to EUCAST v. 14.0 (41).\u003c/p\u003e\n\u003cp\u003eAs nonsusceptible strains, strains resistant to and with intermediate susceptibility were identified.\u003c/p\u003e\n\u003cp\u003e2.4. \u003cstrong\u003eStatistics\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eTo evaluate the relationship between the occurrence of AB infections and non-AB infections in the context of primary infection types, a chi-square test of independence was conducted. Crosstabulations were constructed to present the observed frequencies for each combination of variables, and the chi-square statistic was calculated. Symmetric measures, such as the contingency coefficient, were also calculated to evaluate the strength of the association.\u003c/p\u003e\n\u003cp\u003eThe relationship between the year of isolation and resistance to the tested antibiotics was analyzed via Fisher\u0026apos;s exact test.\u003c/p\u003e\n\u003cp\u003eTo analyze the associations between \u003cem\u003eAcinetobacter\u003c/em\u003e species and healthcare settings (hospitals vs. outpatient clinics), Fisher\u0026apos;s exact test was used across all datasets for consistency. The analysis included species with sufficient sample sizes (n \u0026ge; 10): \u003cem\u003eAcinetobacter ursingii, Acinetobacter pittii, Acinetobacter junii, Acinetobacter lwoffii, Acinetobacter bereziniae, Acinetobacter radioresistens, Acinetobacter lactucae\u003c/em\u003e (syn. \u003cem\u003eA. dijkshoorniae\u003c/em\u003e), and \u003cem\u003eAcinetobacter calcoaceticus\u003c/em\u003e. Species with fewer than 10 isolates were excluded because of insufficient data for reliable statistical testing.\u003c/p\u003e\n\u003cp\u003eTo assess the associations between bacterial species and infection types, Fisher\u0026apos;s exact test was applied. This test was chosen to evaluate the relationships among all species and infection types comprehensively. Pairwise Fisher\u0026apos;s exact tests were conducted for each combination of organism and infection type, producing p values indicating statistical significance.\u003c/p\u003e\n\u003cp\u003eAll analyses were performed via IBM SPSS Statistics (v. 29.0.2.0).\u003c/p\u003e"},{"header":"Results","content":"\u003cp\u003eIn total, 1507 strains belonging to the \u003cem\u003eAcinetobacter\u0026nbsp;\u003c/em\u003egenus were isolated between 2021 and 2023 from patients with different types of infections. Of these, 951 (63.1%) belonged to the \u003cem\u003eAcinetobacter baumannii\u003c/em\u003e species, whereas 556 (36.9%) belonged to other \u003cem\u003eAcinetobacter\u003c/em\u003e species.\u003c/p\u003e\n\u003cp\u003eIn 2021, 494 strains were isolated (AB: 348 (70.4%), non-AB 146: (29.6%)); in 2022, 499 strains were isolated (AB: 285 (57.1%), non-AB:214 (42.9%)); and in 2023, 514 strains were isolated (AB: 318 (61.9%), non-AB: 196 (38.1%)). Among all non-AB strains, 148 (26.6%) were isolated from hospital patients, whereas 408 strains (73.4%) were isolated from outpatients.\u003c/p\u003e\n\u003cp\u003eFor 109 of all the non-AB isolated strains, susceptibility testing was not performed (due to the high number of other bacterial species isolated from the sample or classification of the isolated strain identified as part of the physiological flora without clinical significance). Therefore, a total of 447 strains were included in the final analysis of this study, comprising 123 strains from 2021, 171 from 2022, and 153 from 2023. Among these strains, 118 strains (26.4%) came from hospitalized patients, whereas 329 (73.6%) were from outpatients (Table 1). The median age of the patients, of whom 53% (n=237) were women, was 58 years (Q1=37, Q3=72 years). The region of origin of the isolates and their distribution per hospital are displayed in Figure 1.\u003c/p\u003e\n\u003cp\u003eAmong all the samples, in 171, only one strain was isolated (monoculture). In the remaining 276 samples, other accompanying stains were identified. Overall, the highest number of infections caused by non-AB strains (n=132) was associated with Gram-positive cocci, primarily \u003cem\u003eEnterococcus faecalis\u003c/em\u003e. In 82 patients, the accompanying flora consisted of Enterobacterales, whereas in 47 patients, nonfermenting rods were identified. The highest prevalence of accompanying flora was observed in skin and soft tissue infections (SSTI), where in 71.6% of cases, non-AB strains were accompanied by other species.\u003c/p\u003e\n\u003cp\u003eIn total, 27 non-AB species were identified. The majority of strains were \u003cem\u003eA. ursingii\u003c/em\u003e species (n=135, 30,2%), followed by \u003cem\u003eA. pittii\u0026nbsp;\u003c/em\u003e(n=92, 20,6%) and \u003cem\u003eA. junii\u003c/em\u003e (n=58, 13%). The highest number of non-AB strains was isolated in 2022 (n=171, 38.3%). The species more frequently isolated from hospitalized patients than from outpatients were \u003cem\u003eA. bereziniae\u003c/em\u003e, \u003cem\u003eA. calcoaceticus\u003c/em\u003e, and \u003cem\u003eA. proteolyticus\u003c/em\u003e. A detailed breakdown of the isolated species can be found in Table 1\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eTable 1. Species isolated from infections from hospitalized patients and outpatients b\u003c/strong\u003e\u003cstrong\u003ey year.\u003c/strong\u003e\u003c/p\u003e\n\u003ctable border=\"0\" cellspacing=\"0\" cellpadding=\"0\" width=\"1059\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 189px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eSpecies\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eNumber of all isolates\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003eN\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003e100%\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"3\" style=\"width: 161px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eYear of isolation\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" style=\"width: 170px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eUnit\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eNumber of isolates qualified to analysis\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003eN\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003e100%\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"3\" style=\"width: 199px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eYear of isolation\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" style=\"width: 189px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eUnit\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 189px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e2021\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003en (%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e2022\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003en (%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e2023\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003en (%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eHospital\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003en (%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eOutpatients\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003en (%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e2021\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003en (%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e2022\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003en (%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e2023\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003en (%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 94px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eHospital\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003en (%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 95px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eOutpatients\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003en (%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 189px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter ursingii\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e164\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e50 (30.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e70 (42.7)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e44 (26.8)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e24\u003c/p\u003e\n \u003cp\u003e(14.7)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e140\u003c/p\u003e\n \u003cp\u003e(85.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e135\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e43\u003c/p\u003e\n \u003cp\u003e(31.8)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e56\u003c/p\u003e\n \u003cp\u003e(41.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e36\u003c/p\u003e\n \u003cp\u003e(26.7)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 94px;\"\u003e\n \u003cp\u003e18\u003c/p\u003e\n \u003cp\u003e(13.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 95px;\"\u003e\n \u003cp\u003e117\u003c/p\u003e\n \u003cp\u003e(86.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 189px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter pittii\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e111\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e25 (22.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e48 (43.2)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e38 (34.2)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e35\u003c/p\u003e\n \u003cp\u003e(31.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e76\u003c/p\u003e\n \u003cp\u003e(68.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e92\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e20\u003c/p\u003e\n \u003cp\u003e(21.7)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e40\u003c/p\u003e\n \u003cp\u003e(43.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e32\u003c/p\u003e\n \u003cp\u003e(34.8)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 94px;\"\u003e\n \u003cp\u003e27\u003c/p\u003e\n \u003cp\u003e(29.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 95px;\"\u003e\n \u003cp\u003e65\u003c/p\u003e\n \u003cp\u003e(70.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 189px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter junii\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e63\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e16 (25.4)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e28 (44.4)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e19 (30.2)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e9\u003c/p\u003e\n \u003cp\u003e(14.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e54\u003c/p\u003e\n \u003cp\u003e(85.7)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e58\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e15\u003c/p\u003e\n \u003cp\u003e(25.9)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e26\u003c/p\u003e\n \u003cp\u003e(44.8)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e17\u003c/p\u003e\n \u003cp\u003e(29.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 94px;\"\u003e\n \u003cp\u003e9\u003c/p\u003e\n \u003cp\u003e(15.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 95px;\"\u003e\n \u003cp\u003e49\u003c/p\u003e\n \u003cp\u003e(84.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 189px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter lwoffii\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e52\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e13 (25.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e19 (36.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e20 (38.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e22\u003c/p\u003e\n \u003cp\u003e(42.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e30\u003c/p\u003e\n \u003cp\u003e(57.7)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e37\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e11\u003c/p\u003e\n \u003cp\u003e(29.7)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e12\u003c/p\u003e\n \u003cp\u003e(32.4)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e14\u003c/p\u003e\n \u003cp\u003e(37.8)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 94px;\"\u003e\n \u003cp\u003e17\u003c/p\u003e\n \u003cp\u003e(45.9)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 95px;\"\u003e\n \u003cp\u003e20\u003c/p\u003e\n \u003cp\u003e(54.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 189px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter bereziniae\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e26\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e12 (46.2)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e8 (30.8)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e6 (23.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e16\u003c/p\u003e\n \u003cp\u003e(61.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e10\u003c/p\u003e\n \u003cp\u003e(38.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e22\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e9\u003c/p\u003e\n \u003cp\u003e(40.9)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e6\u003c/p\u003e\n \u003cp\u003e(27.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e7\u003c/p\u003e\n \u003cp\u003e(31.8)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 94px;\"\u003e\n \u003cp\u003e14\u003c/p\u003e\n \u003cp\u003e(63.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 95px;\"\u003e\n \u003cp\u003e8\u003c/p\u003e\n \u003cp\u003e(36.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 189px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter radioresistens\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e21\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e5 (23.8)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e8 (38.1)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e8 (38.1)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e5\u003c/p\u003e\n \u003cp\u003e(23.8)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e16\u003c/p\u003e\n \u003cp\u003e(76.2)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e19\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e4\u003c/p\u003e\n \u003cp\u003e(21.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e8\u003c/p\u003e\n \u003cp\u003e(42.1)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e7\u003c/p\u003e\n \u003cp\u003e(36.8)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 94px;\"\u003e\n \u003cp\u003e5\u003c/p\u003e\n \u003cp\u003e(26.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 95px;\"\u003e\n \u003cp\u003e14\u003c/p\u003e\n \u003cp\u003e(73.7)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 189px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter lactucae (synonym dijkshoorniae)\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e21\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e3 (14.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e7 (33.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e11 (52.4)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e4\u003c/p\u003e\n \u003cp\u003e(19.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e17\u003c/p\u003e\n \u003cp\u003e(81.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e14\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003cp\u003e(14.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e5\u003c/p\u003e\n \u003cp\u003e(35.7)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e7\u003c/p\u003e\n \u003cp\u003e(50.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 94px;\"\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003cp\u003e(21.4)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 95px;\"\u003e\n \u003cp\u003e11\u003c/p\u003e\n \u003cp\u003e(78.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 189px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter calcoaceticus\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e19\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e2 (10.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e6 (31.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e11 (57.9)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e9\u003c/p\u003e\n \u003cp\u003e(47.4)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e10\u003c/p\u003e\n \u003cp\u003e(52.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e15\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(6.7)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e5\u003c/p\u003e\n \u003cp\u003e(33.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e9\u003c/p\u003e\n \u003cp\u003e(60.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 94px;\"\u003e\n \u003cp\u003e9\u003c/p\u003e\n \u003cp\u003e(60.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 95px;\"\u003e\n \u003cp\u003e6\u003c/p\u003e\n \u003cp\u003e(40.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 189px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter proteolyticus\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e11\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e5 (45.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e4 (36.4)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e2 (18.2)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e5\u003c/p\u003e\n \u003cp\u003e(45.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e6\u003c/p\u003e\n \u003cp\u003e(31.6)\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e8\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e4\u003c/p\u003e\n \u003cp\u003e(50.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003cp\u003e(37.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(12.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 94px;\"\u003e\n \u003cp\u003e5\u003c/p\u003e\n \u003cp\u003e(62.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 95px;\"\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003cp\u003e(37.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 189px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter hemolyticus\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e11\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e4 (36.4)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e7 (63.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003cp\u003e(27.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e8\u003c/p\u003e\n \u003cp\u003e(72.7)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e7\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003cp\u003e(42.8)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e4\u003c/p\u003e\n \u003cp\u003e(57.1)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 94px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003cp\u003e(28.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 95px;\"\u003e\n \u003cp\u003e5\u003c/p\u003e\n \u003cp\u003e(71.4)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 189px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter johnsonii\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e10\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e1 (10.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e4 (40.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e5 (50.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(10.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e9\u003c/p\u003e\n \u003cp\u003e(90.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e6\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(16.7)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003cp\u003e(33.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003cp\u003e(50.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 94px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(16.7)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 95px;\"\u003e\n \u003cp\u003e5\u003c/p\u003e\n \u003cp\u003e(83.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 189px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter soli\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e6\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e6 (100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e6\u003c/p\u003e\n \u003cp\u003e(100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e5\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e5\u003c/p\u003e\n \u003cp\u003e(100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 94px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 95px;\"\u003e\n \u003cp\u003e5\u003c/p\u003e\n \u003cp\u003e(100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 189px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter guillouiae\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e9\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e1 (11.1)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e8 (88.9)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003cp\u003e(33.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e6\u003c/p\u003e\n \u003cp\u003e(66.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e5\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(20.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e4\u0026nbsp;(80.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 94px;\"\u003e\n \u003cp\u003e1 (20.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 95px;\"\u003e\n \u003cp\u003e4\u003c/p\u003e\n \u003cp\u003e(80.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 189px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter noscomialis\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e6\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e5 (83.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(16.7)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003cp\u003e(33.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e4\u003c/p\u003e\n \u003cp\u003e(66.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e5\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e5\u003c/p\u003e\n \u003cp\u003e(100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 94px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003cp\u003e(40.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 95px;\"\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003cp\u003e(60.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 189px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter towneri\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e3\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e2 (66.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e1 (33.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(33.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003cp\u003e(66.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e3\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003cp\u003e(66.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(33.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 94px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(33.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 95px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003cp\u003e(66.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 189px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter schindleri\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e3\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e2 (66.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(33.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(33.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003cp\u003e(66.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e3\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e2 (66.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(33.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 94px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(33.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 95px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003cp\u003e(66.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 189px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter variabilis\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e3\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e1 (33.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e2 (66.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003cp\u003e(66.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(33.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e2\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003cp\u003e(100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 94px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(50.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 95px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(50.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 189px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter venetianus\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e2\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e2 (100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003cp\u003e(100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e2\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003cp\u003e(100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 94px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 95px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003cp\u003e(100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 189px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter dispersus\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e4\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e4 (100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003cp\u003e(75.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(25.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e2\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003cp\u003e(100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 94px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(50.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 95px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(50.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 189px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter parvus\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e1\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e1 (100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e1\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e1 (100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 94px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 95px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 189px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter kookii\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e1\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e1 (100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e1\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 94px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 95px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 189px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter modestus\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e1\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e1 (100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e1\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 94px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 95px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 189px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter gyllenbergii\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e2\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e2 (100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003cp\u003e(100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e1\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 94px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 95px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 189px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter beijerinckii\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e1\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e1 (100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e1\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 94px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 95px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 189px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter indicus\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e1\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e1 (100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e1\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 94px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 95px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 189px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter seifertii\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e2\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e1 (50.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e1 (50.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(50.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(50.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e1\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 94px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 95px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 189px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter colistiniresistens\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e1\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e1 (100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e0\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 94px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 95px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 189px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter defluvii\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e1\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e1 (100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e0\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 94px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 95px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 189px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eTotal\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e556\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003e(100)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e146 (26,3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e214 (38,5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 54px;\"\u003e\n \u003cp\u003e196 (35,2)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e148\u003c/p\u003e\n \u003cp\u003e(26,6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e408\u003c/p\u003e\n \u003cp\u003e(73,4)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e447\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003e(100)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e123 (27,5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e171\u003c/p\u003e\n \u003cp\u003e(38,3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e153 (34,2)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 94px;\"\u003e\n \u003cp\u003e118\u003c/p\u003e\n \u003cp\u003e(26,4)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 95px;\"\u003e\n \u003cp\u003e329\u003c/p\u003e\n \u003cp\u003e(73,6)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp\u003eA statistically significant association was observed between \u003cem\u003eAcinetobacter ursingii\u003c/em\u003e and \u003cem\u003eAcinetobacter pittii\u003c/em\u003e, with \u003cem\u003eA. ursingii\u003c/em\u003e being more prevalent in outpatient clinics (86.6%) than \u003cem\u003eA. pittii\u003c/em\u003e (70.6%) (p=0.003). Similarly, \u003cem\u003eA. ursingii\u003c/em\u003e was significantly associated with outpatient settings compared with \u003cem\u003eAcinetobacter bereziniae\u003c/em\u003e (36.3%), which was more frequently isolated in hospitals (p\u0026lt;0.001). Significant differences were also noted between \u003cem\u003eA. ursingii\u003c/em\u003e and \u003cem\u003eAcinetobacter calcoaceticus\u003c/em\u003e, where \u003cem\u003eA. calcoaceticus\u003c/em\u003e was predominantly found in hospitals (60.0%) (p=0.003).\u003c/p\u003e\n\u003cp\u003eFor other comparisons, such as \u003cem\u003eA. ursingii\u003c/em\u003e vs. \u003cem\u003eA. lwoffii\u003c/em\u003e or \u003cem\u003eA. pittii\u003c/em\u003e vs. \u003cem\u003eA. junii\u003c/em\u003e, no statistically significant differences were detected in their distributions between hospitals and outpatient clinics (p\u0026gt;0.05). Species with fewer than 10 isolates were excluded from the analysis because of insufficient sample size.\u003c/p\u003e\n\u003cp\u003eAmong all the samples, 213 non-AB strains were obtained from genitourinary tract infections, 155 from skin and soft tissue infections (SSTIs), 43 from invasive infections (including 20 strains from bloodstream infections) and 36 from other types of infections. Among 951 AB strains, 387 were from SSTIs, 371 from invasive infections, 181 from genitourinary tract infections and 9 from other types of infections. Non-AB strains (87%) dominated AB strains (13%) in genital tract infections, whereas AB strains were more prevalent in invasive infections, accounting for 90% of lower respiratory tract infections and 90% of bloodstream infections (BSIs). A comprehensive overview of the proportions for each infection type is provided in Table 2. The relative frequency according to the type of infection is shown in Figure 2. A statistically significant relationship was found between the presence of AB and primary infection type, as determined by the chi-square test of independence (\u0026chi;\u0026sup2;(3) = 228.891, p \u0026lt; 0.001). The observed frequencies indicated that AB were predominantly associated with invasive infections (n=374, 39.3%) and SSTIs (n=387, 40.7%), whereas non-AB species were more frequently observed in the genitourinary tract category (n=213, 47.7%). The contingency coefficient was 0.375 (p \u0026lt; 0.001), suggesting a moderate association between the variables. Additional correlation analysis revealed weak yet statistically significant inverse associations, with Pearson\u0026rsquo;s R and Spearman\u0026rsquo;s correlation coefficients of -0.109 and -0.110, respectively (p \u0026lt; 0.001).\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eTable 2. Isolates from different types of infections from patients by year.\u003c/strong\u003e\u003c/p\u003e\n\u003ctable border=\"0\" cellspacing=\"0\" cellpadding=\"0\" width=\"913\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"3\" style=\"width: 147px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eInfection type\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"7\" style=\"width: 333px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003enon A. baumannii\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"7\" style=\"width: 336px;\"\u003e\n \u003col start=\"1\" type=\"A\"\u003e\n \u003cli\u003e\u003cstrong\u003e\u003cem\u003ebaumannii\u003c/em\u003e\u003c/strong\u003e\u003c/li\u003e\n \u003c/ol\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"3\" style=\"width: 97px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e% of non-AB in total number of \u003cem\u003eAcinetobacterspp\u003c/em\u003e. strains\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd colspan=\"2\" style=\"width: 97px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e2021\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" style=\"width: 83px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e2022\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" style=\"width: 97px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e2023\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e\u003cstrong\u003etotal\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" style=\"width: 96px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e2021\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" style=\"width: 96px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e2022\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" style=\"width: 96px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e2023\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e\u003cstrong\u003etotal\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u003cstrong\u003en\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u003cstrong\u003en\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 51px;\"\u003e\n \u003cp\u003e%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e\u003cstrong\u003en\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e\u003cstrong\u003en\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e\u003cstrong\u003en\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e\u003cstrong\u003en\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e\u003cstrong\u003en\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e\u003cstrong\u003en\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd colspan=\"7\" style=\"width: 424px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eGenitourinary infections\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e213\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"6\" style=\"width: 288px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eGenitourinary infections\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e181\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 97px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e54%\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 147px;\"\u003e\n \u003cp\u003e\u003cem\u003eUrinary tract infection\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e36\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e28%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e52\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 51px;\"\u003e\n \u003cp\u003e41%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e39\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e31%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e127\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e61\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e36%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e52\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e31%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e55\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e33%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e168\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 97px;\"\u003e\n \u003cp\u003e43%\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 147px;\"\u003e\n \u003cp\u003e\u003cem\u003eGenital tract infection\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e27\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e31%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e32\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 51px;\"\u003e\n \u003cp\u003e37%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e27\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e31%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e86\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e38%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e15%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e6\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e46%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e13\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 97px;\"\u003e\n \u003cp\u003e87%\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd colspan=\"7\" style=\"width: 424px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eSSTI\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e155\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"6\" style=\"width: 288px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eSSTI\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e387\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 97px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e29%\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 147px;\"\u003e\n \u003cp\u003e\u003cem\u003eWounds infection\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e27\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e25%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e40\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 51px;\"\u003e\n \u003cp\u003e37%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e42\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e39%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e109\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e58\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e21%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e104\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e38%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e109\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e40%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e271\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 97px;\"\u003e\n \u003cp\u003e29%\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 147px;\"\u003e\n \u003cp\u003e\u003cem\u003eSkin infection\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e36%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e7\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 51px;\"\u003e\n \u003cp\u003e32%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e7\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e32%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e22\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e12%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e11\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e32%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e19\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e56%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e34\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 97px;\"\u003e\n \u003cp\u003e39%\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 147px;\"\u003e\n \u003cp\u003e\u003cem\u003eUlcers\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e21%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e11\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 51px;\"\u003e\n \u003cp\u003e46%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e33%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e24\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e23\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e28%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e30\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e37%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e29\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e35%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e82\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 97px;\"\u003e\n \u003cp\u003e23%\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd colspan=\"7\" style=\"width: 424px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eInvasive infections\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e43\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"6\" style=\"width: 288px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eInvasive infections\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e374\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 97px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e10%\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 147px;\"\u003e\n \u003cp\u003e\u003cem\u003eRespiratory tract infection\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e7\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e33%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 51px;\"\u003e\n \u003cp\u003e38%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e6\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e29%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e21\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e115\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e59%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e33\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e17%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e47\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e24%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e195\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 97px;\"\u003e\n \u003cp\u003e10%\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 147px;\"\u003e\n \u003cp\u003e\u003cem\u003eBloodstream infection\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e25%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e10\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 51px;\"\u003e\n \u003cp\u003e50%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e25%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e20\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e78\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e40%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e53\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e27%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e48\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e25%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e179\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 97px;\"\u003e\n \u003cp\u003e10%\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 147px;\"\u003e\n \u003cp\u003e\u003cem\u003eCentral nervous system infection\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 51px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e100%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e0%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e0%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e0%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 97px;\"\u003e\n \u003cp\u003e100%\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd colspan=\"7\" style=\"width: 424px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eOthers\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e36\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"6\" style=\"width: 288px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eOthers\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e9\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 97px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e80%\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 147px;\"\u003e\n \u003cp\u003e\u003cem\u003eEars infection\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e19%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e7\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 51px;\"\u003e\n \u003cp\u003e33%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e10\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e48%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e21\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e50%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e0%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e50%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 97px;\"\u003e\n \u003cp\u003e72%\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 147px;\"\u003e\n \u003cp\u003e\u003cem\u003eEye infection\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e21%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 51px;\"\u003e\n \u003cp\u003e29%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e7\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e50%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e14\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e0%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e0%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e100%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 97px;\"\u003e\n \u003cp\u003e93%\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 147px;\"\u003e\n \u003cp\u003e\u003cem\u003eArthritis infection\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e100%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 51px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 32px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 65px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 97px;\"\u003e\n \u003cp\u003e100%\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp\u003e\u003cstrong\u003eLegend: non-AB- \u003cem\u003enon-A. baumannii;\u0026nbsp;\u003c/em\u003eSSTI\u003cem\u003e\u0026nbsp;\u0026ndash; skin and soft tissue infections\u003c/em\u003e\u003cem\u003e.\u0026nbsp;\u003c/em\u003eThe percentage in each column represents the proportion of strains isolated in a given year relative to the total number of strains isolated from the same type of infection across all years.\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eTable 3 presents the distributions of individual species in relation to the type of infection.\u003cem\u003e\u0026nbsp;A. ursingii\u0026nbsp;\u003c/em\u003epredominated in genitourinary infections (n=80, 37.6%), followed by \u003cem\u003eA. junii\u0026nbsp;\u003c/em\u003e(n=38, 17.8%). Similarly, among the SSTIs, \u003cem\u003eA. ursingii\u0026nbsp;\u003c/em\u003e(n=41, 26.5%) was the most common, followed by\u003cem\u003e\u0026nbsp;A. pittii\u003c/em\u003e (n=39, 25.2%). The pattern was different for invasive infections, where \u003cem\u003eA. pittii\u0026nbsp;\u003c/em\u003e(n=13, 30.2%) was dominant, followed by \u003cem\u003eA. lwoffii\u003c/em\u003e (n=7, 16.3%) and \u003cem\u003eA. bereziniae\u003c/em\u003e (n=7, 16.3%). The most common strains among bloodstream infections (n=20) were \u003cem\u003eA. lwoffii\u0026nbsp;\u003c/em\u003eand \u003cem\u003eA. pittii\u003c/em\u003e, which were each isolated from 5 (25%) cases of BSI.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eTable 3. Distribution of individual species in relation to the type of infection.\u003c/strong\u003e\u003c/p\u003e\n\u003ctable border=\"0\" cellspacing=\"0\" cellpadding=\"0\" width=\"612\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 183px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eInfection type\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 103px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eGenitourinary tract infections\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 59px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eSSTI\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eInvasive infections\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 74px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eOthers\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" style=\"width: 113px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eTotal\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\" style=\"width: 183px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eSpecies\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 103px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e213\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 59px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e155\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 80px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e43\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 74px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e36\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 57px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e447\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 56px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e100%\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\" style=\"width: 183px;\"\u003e\n \u003cp\u003e\u003cem\u003eAcinetobacter ursingii\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 103px;\"\u003e\n \u003cp\u003e80\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 59px;\"\u003e\n \u003cp\u003e41\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 80px;\"\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 74px;\"\u003e\n \u003cp\u003e11\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 57px;\"\u003e\n \u003cp\u003e135\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e30,2%\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\" style=\"width: 183px;\"\u003e\n \u003cp\u003e\u003cem\u003eAcinetobacter pittii\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 103px;\"\u003e\n \u003cp\u003e35\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 59px;\"\u003e\n \u003cp\u003e39\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 80px;\"\u003e\n \u003cp\u003e13\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 74px;\"\u003e\n \u003cp\u003e5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 57px;\"\u003e\n \u003cp\u003e92\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e20,6%\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\" style=\"width: 183px;\"\u003e\n \u003cp\u003e\u003cem\u003eAcinetobacter junii\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 103px;\"\u003e\n \u003cp\u003e38\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 59px;\"\u003e\n \u003cp\u003e11\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 80px;\"\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 74px;\"\u003e\n \u003cp\u003e6\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 57px;\"\u003e\n \u003cp\u003e58\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e13,0%\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\" style=\"width: 183px;\"\u003e\n \u003cp\u003e\u003cem\u003eAcinetobacter lwoffii\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 103px;\"\u003e\n \u003cp\u003e18\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 59px;\"\u003e\n \u003cp\u003e10\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 80px;\"\u003e\n \u003cp\u003e7\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 74px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 57px;\"\u003e\n \u003cp\u003e37\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e8,3%\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\" style=\"width: 183px;\"\u003e\n \u003cp\u003e\u003cem\u003eAcinetobacter bereziniae\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 103px;\"\u003e\n \u003cp\u003e4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 59px;\"\u003e\n \u003cp\u003e7\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 80px;\"\u003e\n \u003cp\u003e7\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 74px;\"\u003e\n \u003cp\u003e4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 57px;\"\u003e\n \u003cp\u003e22\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e4,9%\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\" style=\"width: 183px;\"\u003e\n \u003cp\u003e\u003cem\u003eAcinetobacter radioresistens\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 103px;\"\u003e\n \u003cp\u003e9\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 59px;\"\u003e\n \u003cp\u003e9\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 80px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 74px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 57px;\"\u003e\n \u003cp\u003e19\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e4,3%\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\" style=\"width: 183px;\"\u003e\n \u003cp\u003e\u003cem\u003eAcinetobacter calcoaceticus\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 103px;\"\u003e\n \u003cp\u003e4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 59px;\"\u003e\n \u003cp\u003e7\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 80px;\"\u003e\n \u003cp\u003e4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 74px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 57px;\"\u003e\n \u003cp\u003e15\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e3,4%\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 183px;\"\u003e\n \u003cp\u003e\u003cem\u003eAcinetobacter lactucae (synonym dijkshoorniae)\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 103px;\"\u003e\n \u003cp\u003e4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 59px;\"\u003e\n \u003cp\u003e6\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 74px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e14\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e3,1%\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\" style=\"width: 183px;\"\u003e\n \u003cp\u003e\u003cem\u003eAcinetobacter proteolyticus\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 103px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 59px;\"\u003e\n \u003cp\u003e4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 80px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 74px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 57px;\"\u003e\n \u003cp\u003e8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e1,8%\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\" style=\"width: 183px;\"\u003e\n \u003cp\u003e\u003cem\u003eAcinetobacter hemolyticus\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 103px;\"\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 59px;\"\u003e\n \u003cp\u003e4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 80px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 74px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 57px;\"\u003e\n \u003cp\u003e7\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e1,6%\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\" style=\"width: 183px;\"\u003e\n \u003cp\u003e\u003cem\u003eAcinetobacter johnsonii\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 103px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 59px;\"\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 80px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 74px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 57px;\"\u003e\n \u003cp\u003e6\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e1,3%\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\" style=\"width: 183px;\"\u003e\n \u003cp\u003e\u003cem\u003eAcinetobacter soli\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 103px;\"\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 59px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 80px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 74px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 57px;\"\u003e\n \u003cp\u003e5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e1,1%\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\" style=\"width: 183px;\"\u003e\n \u003cp\u003e\u003cem\u003eAcinetobacter guillouiae\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 103px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 59px;\"\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 80px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 74px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 57px;\"\u003e\n \u003cp\u003e5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e1,1%\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\" style=\"width: 183px;\"\u003e\n \u003cp\u003e\u003cem\u003eAcinetobacter noscomialis\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 103px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 59px;\"\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 80px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 74px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 57px;\"\u003e\n \u003cp\u003e5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e1,1%\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\" style=\"width: 183px;\"\u003e\n \u003cp\u003e\u003cem\u003eAcinetobacter towneri\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 103px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 59px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 80px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 74px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 57px;\"\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e0,7%\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\" style=\"width: 183px;\"\u003e\n \u003cp\u003e\u003cem\u003eAcinetobacter schindleri\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 103px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 59px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 80px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 74px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 57px;\"\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e0,7%\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\" style=\"width: 183px;\"\u003e\n \u003cp\u003e\u003cem\u003eAcinetobacter variabilis\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 103px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 59px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 80px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 74px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 57px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e0,4%\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\" style=\"width: 183px;\"\u003e\n \u003cp\u003e\u003cem\u003eAcinetobacter venetianus\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 103px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 59px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 80px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 74px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 57px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e0,4%\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\" style=\"width: 183px;\"\u003e\n \u003cp\u003e\u003cem\u003eAcinetobacter dispersus\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 103px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 59px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 80px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 74px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 57px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e0,4%\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\" style=\"width: 183px;\"\u003e\n \u003cp\u003e\u003cem\u003eAcinetobacter parvus\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 103px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 59px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 80px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 74px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 57px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e0,2%\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\" style=\"width: 183px;\"\u003e\n \u003cp\u003e\u003cem\u003eAcinetobacter kookii\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 103px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 59px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 80px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 74px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 57px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e0,2%\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\" style=\"width: 183px;\"\u003e\n \u003cp\u003e\u003cem\u003eAcinetobacter modestus\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 103px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 59px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 80px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 74px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 57px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e0,2%\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\" style=\"width: 183px;\"\u003e\n \u003cp\u003e\u003cem\u003eAcinetobacter gyllenbergii\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 103px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 59px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 80px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 74px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 57px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e0,2%\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\" style=\"width: 183px;\"\u003e\n \u003cp\u003e\u003cem\u003eAcinetobacter beijerinckii\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 103px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 59px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 80px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 74px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 57px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e0,2%\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\" style=\"width: 183px;\"\u003e\n \u003cp\u003e\u003cem\u003eAcinetobacter indicus\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 103px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 59px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 80px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 74px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 57px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e0,2%\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"bottom\" style=\"width: 183px;\"\u003e\n \u003cp\u003e\u003cem\u003eAcinetobacter seifertii\u003c/em\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 103px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 59px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 80px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 74px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"bottom\" style=\"width: 57px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 56px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e0,2%\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 183px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eTotal non-A.baumannii\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 103px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e213\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 59px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e155\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e43\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 74px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e36\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" style=\"width: 113px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e447\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 183px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter baumannii\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 103px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e181\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 59px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e387\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 80px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e374\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 74px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e9\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" style=\"width: 113px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e951\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp\u003e\u003cstrong\u003eLegend: The percentage was calculated as the proportion of a given species in the total number of infections of that type.\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eFisher\u0026apos;s exact test revealed the following associations for bacterial species and infection types. \u003cem\u003eAcinetobacter bereziniae\u003c/em\u003e was significantly associated with genitourinary tract infections and invasive infections (p\u0026lt;0.05). \u003cem\u003eAcinetobacter junii\u003c/em\u003e and \u003cem\u003eAcinetobacter pittii\u003c/em\u003e were significantly associated with genitourinary tract infections and SSTIs (p\u0026lt;0.05). \u003cem\u003eAcinetobacter ursingii\u003c/em\u003e was significantly associated with genitourinary tract infections and invasive infections (p\u0026lt;0.05).\u003c/p\u003e\n\u003cp\u003e\u003cem\u003eAcinetobacter lwoffii\u003c/em\u003e was not significantly associated with specific infection types (p\u0026gt;0.05) across all tested infection types. Among all the isolated strains, 50 (11.1%) were nonsusceptible to ampicillin/sulbactam, 4 (0.9%) to imipenem, 7 (1.6%) to meropenem, 11 (2.5%) to amikacin, 13 (2.9%) to gentamycin, 6 (1.3%) tobramycin, 26 to trimethoprim/sulfamethoxazole (5.8%) and 7 (1.6) to colistin (Table 4). Almost all the isolated strains (98.4%) were nonsusceptible to ciprofloxacin (19 were resistant, and 421 were characterized by intermediate susceptibility).\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eTable 4. Number of strains nonsusceptible to selected antimicrobials among different types of infections.\u003c/strong\u003e\u003c/p\u003e\n\u003ctable border=\"1\" cellspacing=\"0\" cellpadding=\"0\" width=\"690\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"2\" style=\"width: 104px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eInfection type\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"9\" valign=\"top\" style=\"width: 586px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eTested antimicrobials and number of\u0026nbsp;\u003c/strong\u003e\u003cstrong\u003enonsusceptible strains\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eAMP\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003e/SUL\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003eN\u003cbr\u003e\u0026nbsp;(%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eIMI\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003eN\u003cbr\u003e\u0026nbsp;(%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eMEM\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003eN\u003cbr\u003e\u0026nbsp;(%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eCIP\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003eN\u003cbr\u003e\u0026nbsp;(%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eAK\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003eN\u003cbr\u003e\u0026nbsp;(%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eGEN\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003eN\u003cbr\u003e\u0026nbsp;(%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eTOB\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003eN\u003cbr\u003e\u0026nbsp;(%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eCOL\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003eN\u003cbr\u003e\u0026nbsp;(%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eSXT\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003eN\u003cbr\u003e\u0026nbsp;(%)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 104px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eGenitourinary tract\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e33\u003c/p\u003e\n \u003cp\u003e(7.4%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(0.2%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003cp\u003e(0.4%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e212 (47.4%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e7\u003c/p\u003e\n \u003cp\u003e(1.6%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003cp\u003e(0.7%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003cp\u003e(0.7%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e6\u003c/p\u003e\n \u003cp\u003e(1.3%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e9\u003c/p\u003e\n \u003cp\u003e(2%)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 104px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eSSTI\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e11\u003c/p\u003e\n \u003cp\u003e(2.5%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(0.2%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003cp\u003e(0.4%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e150 (33.6%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003cp\u003e(0.4%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e5\u003c/p\u003e\n \u003cp\u003e(1.1%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003cp\u003e(0.4%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(0.2%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e9\u003c/p\u003e\n \u003cp\u003e(2%)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 104px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eInvasive infections\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003cp\u003e(0.7%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003cp\u003e(0.4%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003cp\u003e(0.4%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e42\u003c/p\u003e\n \u003cp\u003e(9.4%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(0.2%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003cp\u003e(0.4%)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 104px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eOthers\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003cp\u003e(0.7%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(0.2%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e36\u003c/p\u003e\n \u003cp\u003e(8.1%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003cp\u003e(0.4%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e4\u003c/p\u003e\n \u003cp\u003e(0.9%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(0.2%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e-\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e6\u003c/p\u003e\n \u003cp\u003e(1.3%)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 104px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eTotal\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e50 (11.1%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e4\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003e(0.9%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e7\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003e(1.6%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e440 (98.4%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e11 (2.5%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e13\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003e(2.9%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e6\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003e(1.3%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e7\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003e(1.6%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 65px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e26\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003e(5.8%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp\u003e\u003cstrong\u003eLegend: The percentage represents the proportion of nonsusceptible strains for antimicrobial agents relative to the total number of strains isolated from infections of that type. AMP/SUL\u0026mdash;ampililin/sulbactam; IMI\u0026mdash;imipenem; MEM\u0026mdash;meropenem; CIP\u0026mdash;ciprofloxacin; AK\u0026mdash;amikacin; GEN\u0026mdash;gentamicin; TOB\u0026mdash;tobramycin; SXT\u0026mdash;trimethoprim/sulfamethoxazole; COL\u0026mdash;colistin.\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe nonsusceptibility of non-AB strains during the studied years is presented in Figure 3. Across all years, the highest rates of nonsusceptibility were observed for ciprofloxacin, ampicillin-sulbactam, and trimethoprim/sulfamethoxazole. The analysis revealed no statistically significant differences in resistance to any of the tested antibiotics (ampicillin/sulbactam; imipenem; meropenem; ciprofloxacin; amikacin; gentamicin; tobramycin; trimethoprim/sulfamethoxazole; colistin) from 2021\u0026ndash;2023 (p\u0026gt;0.05 for all tests). These findings suggest that resistance patterns were stable during the study period.\u003c/p\u003e\n\u003cp\u003eFive non-AB species accounted for nearly 77% of all the isolated strains. Table 5 presents the nonsusceptibility patterns of strains isolated in quantities exceeding 20 over a three-year period. Across all the species, high nonsusceptibility to ciprofloxacin was observed (89.2% for \u003cem\u003eA. lwoffii\u003c/em\u003e and 100% for \u003cem\u003eA. pittii\u003c/em\u003e or \u003cem\u003eA. junii\u003c/em\u003e). Additionally, among \u003cem\u003eA. bereziniae\u003c/em\u003e strains, relatively high percentages were nonsusceptible to carbapenems (9.1% for imipenem, 13.6% for meropenem), aminoglycosides (13.6% for amikacin, 22.7% for gentamycin), and trimethoprim/sulfamethoxazole (31.8%). Resistance to colistin was noted in \u003cem\u003eA. ursingii\u003c/em\u003e and \u003cem\u003eA. pittii\u003c/em\u003e strains.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eTable 5.\u0026nbsp;\u003c/strong\u003e\u003cstrong\u003eA detailed characterization of the most frequently isolated species (n\u0026gt;20).\u003c/strong\u003e\u003c/p\u003e\n\u003ctable border=\"1\" cellspacing=\"0\" cellpadding=\"0\" width=\"690\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"2\" style=\"width: 161px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eGenus\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003eN 100%\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"9\" style=\"width: 529px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eTested antimicrobials and number of\u0026nbsp;\u003c/strong\u003e\u003cstrong\u003enonsusceptible strains\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eAMP/SUL\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003eN\u003c/p\u003e\n \u003cp\u003e(%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 57px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eIMI\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003eN\u003c/p\u003e\n \u003cp\u003e(%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 57px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eMEM\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003eN\u003c/p\u003e\n \u003cp\u003e(%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 57px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eCIP\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003eN\u003c/p\u003e\n \u003cp\u003e(%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 57px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eAK\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003eN\u003c/p\u003e\n \u003cp\u003e(%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 57px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eGEN\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003eN\u003c/p\u003e\n \u003cp\u003e(%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 57px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eTOB\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003eN\u003c/p\u003e\n \u003cp\u003e(%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 57px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eCOL\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003eN\u003c/p\u003e\n \u003cp\u003e(%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 57px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eSXT\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003eN\u003c/p\u003e\n \u003cp\u003e(%)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 161px;\"\u003e\n \u003cp\u003e\u003cem\u003eAcinetobacter ursingii\u003c/em\u003e\u003c/p\u003e\n \u003cp\u003e(n=135)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e18\u003c/p\u003e\n \u003cp\u003e(13.3%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003cp\u003e(1.5%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003cp\u003e(2.2%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e133\u003c/p\u003e\n \u003cp\u003e(98.5%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e4\u003c/p\u003e\n \u003cp\u003e(3.0%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003cp\u003e(1.5%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003cp\u003e(1.5%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003cp\u003e(2.2%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e12\u003c/p\u003e\n \u003cp\u003e(8.9%)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 161px;\"\u003e\n \u003cp\u003e\u003cem\u003eAcinetobacter pittii\u003c/em\u003e\u003c/p\u003e\n \u003cp\u003e(n=92)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e7\u003c/p\u003e\n \u003cp\u003e(7.6%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(1.1%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e92\u003c/p\u003e\n \u003cp\u003e(100%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(1.1%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003cp\u003e(3.3%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 161px;\"\u003e\n \u003cp\u003e\u003cem\u003eAcinetobacter junii\u003c/em\u003e\u003c/p\u003e\n \u003cp\u003e(n=58)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e8\u003c/p\u003e\n \u003cp\u003e(13.8%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e58\u003c/p\u003e\n \u003cp\u003e(100%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(1.7%)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 161px;\"\u003e\n \u003cp\u003e\u003cem\u003eAcinetobacter lwoffi\u003c/em\u003e\u003c/p\u003e\n \u003cp\u003e(n=37)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(2.7%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e33\u003c/p\u003e\n \u003cp\u003e(89.2%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003cp\u003e(8.1%)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 161px;\"\u003e\n \u003cp\u003e\u003cem\u003eAcinetobacter bereziniae\u003c/em\u003e\u003c/p\u003e\n \u003cp\u003e(n=22)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 76px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(4.5%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003cp\u003e(9.1%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003cp\u003e(13.6%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e22\u003c/p\u003e\n \u003cp\u003e(100%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003cp\u003e(13.6%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e5\u003c/p\u003e\n \u003cp\u003e(22.7%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e(4.5%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 57px;\"\u003e\n \u003cp\u003e7\u003c/p\u003e\n \u003cp\u003e(31.8%)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp\u003e\u003cstrong\u003eLegend: The percentage of resistant strains in relation to all strains of a given species.\u0026nbsp;\u003c/strong\u003eAMP/SUL\u0026mdash;ampililin/sulbactam; IMI\u0026mdash;imipenem; MEM\u0026mdash;meropenem; CIP\u0026mdash;ciprofloxacin; AK\u0026mdash;amikacin; GEN\u0026mdash;gentamicin; TOB\u0026mdash;tobramycin; SXT\u0026mdash;trimethoprim/sulfamethoxazole; COL\u0026mdash;colistin.\u003c/p\u003e\n\u003cp\u003eAll the strains resistant to colistin were isolated from male outpatients. Five of them originated from urinary tract infections from one outpatient clinic, while the remaining two were from a urinary tract infection and a wound infection from two other outpatient clinics. These strains were susceptible to imipenem and trimethoprim/sulfamethoxazole. Detailed information on colistin-resistant strains is summarized in Table 6.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eTable 6. Detailed data on colistin-resistant strains. R-resistant, S-susceptible.\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n\u003ctable border=\"1\" cellspacing=\"0\" cellpadding=\"0\" width=\"752\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eOutpatient clinic\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 38px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eAge\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eGender\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eInfection type\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 104px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eStrain\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 59px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eAMP/\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003eSUL\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eIMI\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eMEM\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 41px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eCIP\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 39px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eAK\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eGEN\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eTOB\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eSXT\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 38px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e57\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eM\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003eUrinary tract\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 104px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter ursingii\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 59px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 41px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eR\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 39px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 38px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e37\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eM\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003eUrinary tract\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 104px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter ursingii\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 59px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 41px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eR\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 39px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 38px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e81\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eM\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003eUrinary tract\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 104px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter ursingii\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 59px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eR\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 41px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eR\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 39px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eR\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eR\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eR\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 38px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e75\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eM\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003eUrinary tract\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 104px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter pittii\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 59px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 41px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eR\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 39px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 38px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e49\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eM\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003eUrinary tract\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 104px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter lactucae\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 59px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 41px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eR\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 39px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eR\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 38px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e59\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eM\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003eWound\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 104px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter noscomialis\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 59px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 41px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 39px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 38px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e70\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 66px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eM\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 85px;\"\u003e\n \u003cp\u003eUrinary tract\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 104px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcinetobacter pittii\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 59px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 42px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 55px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 41px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eR\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 39px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 48px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 47px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 43px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eS\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp\u003e\u003cstrong\u003e\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e"},{"header":"Discussion","content":"\u003cp\u003eInfections caused by \u003cem\u003eAcinetobacter\u003c/em\u003e spp. have been increasing in prevalence in recent years and are emerging as a global public health concern due to increasing antibiotic resistance in healthcare settings (\u003cspan citationid=\"CR7\" class=\"CitationRef\"\u003e7\u003c/span\u003e, \u003cspan citationid=\"CR8\" class=\"CitationRef\"\u003e8\u003c/span\u003e, \u003cspan citationid=\"CR10\" class=\"CitationRef\"\u003e10\u003c/span\u003e, \u003cspan citationid=\"CR19\" class=\"CitationRef\"\u003e19\u003c/span\u003e, \u003cspan citationid=\"CR38\" class=\"CitationRef\"\u003e38\u003c/span\u003e, \u003cspan citationid=\"CR43\" class=\"CitationRef\"\u003e43\u003c/span\u003e). Epidemiological data from the ECDC 2022\u0026ndash;23 point prevalence study indicated that in Europe, AB is primarily responsible for respiratory and bloodstream infections (European Centre for Disease Prevention and Control (\u003cspan citationid=\"CR44\" class=\"CitationRef\"\u003e44\u003c/span\u003e).\u003c/p\u003e \u003cp\u003eThe WHO has listed carbapenem-resistant AB as a critical-priority pathogen among those bacteria that require the research and development of new drugs (\u003cspan citationid=\"CR29\" class=\"CitationRef\"\u003e29\u003c/span\u003e). According to ECDC data, the percentages of carbapenem-resistant \u003cem\u003eAcinetobacter\u003c/em\u003e spp. varied widely within the European region in 2023, from less than 5% to equal to or greater than 50% in 18 countries, mostly in southern and eastern Europe, including Poland (\u003cspan citationid=\"CR45\" class=\"CitationRef\"\u003e45\u003c/span\u003e). Pandrug-resistant strains are being identified more frequently among AB strains (\u003cspan citationid=\"CR46\" class=\"CitationRef\"\u003e46\u003c/span\u003e). In Poland, there has been a problem with extensively drug-resistant AB strains for many years, especially in intensive care unit (ICU) departments (\u003cspan citationid=\"CR47\" class=\"CitationRef\"\u003e47\u003c/span\u003e, \u003cspan citationid=\"CR48\" class=\"CitationRef\"\u003e48\u003c/span\u003e).\u003c/p\u003e \u003cp\u003eThe results of our current study indicate that although AB is the predominant species, accounting for the majority (63.1%) of isolates from infections between 2021 and 2023, the significant role of non-AB species in clinical infections should also be emphasized. Non-AB infections accounted for an average of 36.9%, with the highest proportion recorded in 2022 at 42.9%. Non-AB species should not be overlooked, particularly in genitourinary infections and skin and soft tissue infections. Additionally, in less common infections, such as ear and eye infections, the majority of strains are non-ABs rather than ABs. Although the frequency of isolation of AB strains was greater among those with SSTIs (71%) and invasive infections (90%), non-AB strains dominated among those with genital tract infections (87%). \u003cem\u003eAcinetobacter\u003c/em\u003e species, particularly non-AB strains, are commonly isolated from genital tract infections due to several factors. These bacteria are opportunistic pathogens that thrive in diverse environments, including the urinary and genital tracts, especially in immunocompromised individuals or those with indwelling devices such as catheters. The ability of these bacteria to survive in the human body and adapt to various conditions, including those in hospital settings, contributes to their frequent isolation in infections. In addition, some species, such as \u003cem\u003eA. pittii\u003c/em\u003e and \u003cem\u003eA. nosocomialis\u003c/em\u003e, have been found in urinary tract infections (\u003cspan citationid=\"CR38\" class=\"CitationRef\"\u003e38\u003c/span\u003e).\u003c/p\u003e \u003cp\u003eThe results suggest that a greater proportion of non-AB strains (73.4%) were isolated from outpatients than from hospital patients (26.6%), indicating that these strains may be more commonly associated with outpatient settings. However, with respect to the detailed distribution of particular strains, \u003cem\u003eA. bereziniae\u003c/em\u003e, \u003cem\u003eA. proteolyticus, A. calcoaceticus\u003c/em\u003e and \u003cem\u003eA. lwoffii\u003c/em\u003e were isolated more frequently from hospitalized patients (63.6%, 62.5%, 60% and 45.9%, respectively) and were connected (together with \u003cem\u003eA. pittii\u003c/em\u003e) with invasive infections. Some reports indicate that \u003cem\u003eA. pittii\u003c/em\u003e and other species of Abc are isolated most often from hospitalized patients and may be transmitted horizontally (\u003cspan citationid=\"CR39\" class=\"CitationRef\"\u003e39\u003c/span\u003e). \u003cem\u003eA. pittii\u003c/em\u003e has increasingly been associated with various types of hospital-acquired infections, including bloodstream infections, ventilator-associated pneumonia, and wound infections (\u003cspan additionalcitationids=\"CR19\" citationid=\"CR18\" class=\"CitationRef\"\u003e18\u003c/span\u003e\u0026ndash;\u003cspan citationid=\"CR20\" class=\"CitationRef\"\u003e20\u003c/span\u003e, \u003cspan citationid=\"CR49\" class=\"CitationRef\"\u003e49\u003c/span\u003e). Similar to other studies, our results have shown that \u003cem\u003eA. pittii\u003c/em\u003e is increasingly recognized in bloodstream infections and accounts for approximately 30.2% of non-AB BSIs in clinical settings (\u003cspan citationid=\"CR49\" class=\"CitationRef\"\u003e49\u003c/span\u003e). \u003cem\u003eA. berezianiae\u003c/em\u003e strains that are resistant to carbapenems are being isolated from hospitalized patients more frequently (\u003cspan citationid=\"CR34\" class=\"CitationRef\"\u003e34\u003c/span\u003e). Studies by Guedes-Stehling et al. demonstrated that \u003cem\u003eA. bereziniae\u003c/em\u003e can be transferred between the natural environment, animals and humans and is a potential One Health bacteria that require close surveillance (\u003cspan citationid=\"CR50\" class=\"CitationRef\"\u003e50\u003c/span\u003e).\u003c/p\u003e \u003cp\u003eThe most commonly isolated species in our study, particularly from outpatient samples, were \u003cem\u003eA. ursingii\u003c/em\u003e, \u003cem\u003eA. junii\u003c/em\u003e, and \u003cem\u003eA. pittii\u003c/em\u003e, with prevalence rates of 86.6%, 84.5%, and 70.6%, respectively. Non-AB strains are frequently isolated from outpatients due to several factors. These species are often part of the normal microbiota in the environment and can cause infections in individuals who are not critically ill or hospitalized. They may also be more prevalent in outpatient settings, where the population typically consists of patients with less severe conditions who are not exposed to the intense antibiotic pressures found in hospitals. Additionally, non-AB species may have a lower degree of resistance than AB, allowing them to persist more easily in outpatient environments​.\u003c/p\u003e \u003cp\u003eImportantly, more than one-third (n\u0026thinsp;=\u0026thinsp;171, 38.3%) of the non-AB strains were isolated from pure cultures. While the pathogenicity of these species remains under investigation, it is possible that these emerging environmental species contribute to infectious processes, particularly in immunocompromised patients, individuals undergoing invasive procedures, or those receiving broad-spectrum antibiotic therapy. The \u003cem\u003eAcinetobacter\u003c/em\u003e genus, known for its intrinsic resistance to desiccation, metabolic adaptability, and role as a reservoir of resistance genes, necessitates isolation, precise species identification and typing for effective epidemiological control in hospitals (\u003cspan citationid=\"CR38\" class=\"CitationRef\"\u003e38\u003c/span\u003e, \u003cspan citationid=\"CR43\" class=\"CitationRef\"\u003e43\u003c/span\u003e).\u003c/p\u003e \u003cp\u003eHowever, in the case of SSTI infections, particularly when chronic wounds are infected, bacteria often form polymicrobial biofilms. In our study, more than one microorganism was isolated from almost two-thirds of the studied samples. This study revealed that non-AB strains are often associated with polymicrobial infections, particularly skin and soft tissue infections (SSTIs), where they frequently coexist with Gram-positive cocci such as \u003cem\u003eEnterococcus faecalis\u003c/em\u003e or \u003cem\u003eStaphylococcus\u003c/em\u003e. The presence of numerous microorganisms in chronic wounds or diabetic ulcers can delay healing, as they not only directly damage tissue but also attract leukocytes and activate inflammatory cytokines and proteases (\u003cspan citationid=\"CR51\" class=\"CitationRef\"\u003e51\u003c/span\u003e). Microbes within biofilms are highly adaptable to harsh conditions, enabling them to survive various treatments, including antibiotics (\u003cspan citationid=\"CR52\" class=\"CitationRef\"\u003e52\u003c/span\u003e).\u003c/p\u003e \u003cp\u003eThe polymicrobial etiology also included infections of the genital tract; in addition to \u003cem\u003eAcinetobacter\u003c/em\u003e strains, \u003cem\u003eE. faecalis\u003c/em\u003e strains are commonly isolated. The vaginal microbiome is continuously changing, especially as bacteria from the gut microbiome may travel down to the female urogenital tract. Opportunistic pathogens can form biofilms that can help them circumvent the potency of antibiotics while simultaneously exerting virulence factors that degrade vaginal epithelial cells in patients (\u003cspan citationid=\"CR53\" class=\"CitationRef\"\u003e53\u003c/span\u003e). Non-AB strains can constitute a significant part of the biofilm formed in genital tract infections and contribute to bacterial vaginosis or aerobic vaginitis.\u003c/p\u003e \u003cp\u003eA statistically significant relationship was found between the presence of AB infections and primary infection types: AB infections were predominantly associated with invasive infections, whereas non-AB species were more frequently observed in the genitourinary tract category. These results suggest a clinically relevant difference in the distribution of infection types between AB and non-AB. AB infections were more strongly associated with invasive and soft tissue infections, whereas non-AB infections were more prevalent in genitourinary infections. Further investigations are warranted to understand the clinical implications of these findings.\u003c/p\u003e \u003cp\u003eThe majority of the isolated strains were susceptible to all the tested antimicrobials. Among the 447 strains analyzed, only a small number of isolates exhibited resistance to critical antibiotics, such as imipenem (0.9%) and meropenem (1.6%), which are important for treating severe infections. The proportion of strains resistant to ampicillin-sulbactam was greater among strains isolated from genitourinary tract infections, which may be related to the fact that this agent is commonly used to treat such infections. Notably, 98.4% of the isolated strains were not susceptible to ciprofloxacin, raising questions about the effectiveness of fluoroquinolones in clinical settings. \u003cem\u003eAcinetobacter\u003c/em\u003e species often possess efflux pumps, which actively expel ciprofloxacin and other antibiotics from bacterial cells, reducing the concentration of the drug inside the cell and decreasing its effectiveness (\u003cspan citationid=\"CR54\" class=\"CitationRef\"\u003e54\u003c/span\u003e). In a similar study in Germany involving specimens collected between 2010 and 2019, 25% of the isolates were resistant to ciprofloxacin (\u003cspan citationid=\"CR55\" class=\"CitationRef\"\u003e55\u003c/span\u003e). The results from the 2020 Spanish nationwide study revealed that 60% of Acinetobacter strains were resistant (\u003cspan citationid=\"CR56\" class=\"CitationRef\"\u003e56\u003c/span\u003e). Fluoroquinolones have historically shown good activity against \u003cem\u003eAcinetobacter\u003c/em\u003e spp., but over the last 20 years, there has been a large increase in fluoroquinolone resistance and multidrug resistance (\u003cspan citationid=\"CR57\" class=\"CitationRef\"\u003e57\u003c/span\u003e). The high resistance to fluoroquinolones in our study may have resulted from the high consumption of this group of antibiotics in Europe. In Poland, the use of fluoroquinolones decreased during the pandemic but has been increasing again since 2022 (\u003cspan citationid=\"CR58\" class=\"CitationRef\"\u003e58\u003c/span\u003e). The large proportion of ciprofloxacin-nonsusceptible strains in our study may also be connected with the chosen methodology. We included resistant strains and those with intermediate susceptibility among the nonsusceptible strains, which resulted in a high percentage of nonsusceptible strains (98.4%). Only 19 (4.3%) strains were resistant to ciprofloxacin, whereas 421 (94.1%) strains exhibited intermediate susceptibility.\u003c/p\u003e \u003cp\u003eMany publications address the problem of the global spread of AB strains resistant to carbapenems and producing acquired carbapenemases (\u003cspan citationid=\"CR59\" class=\"CitationRef\"\u003e59\u003c/span\u003e, \u003cspan citationid=\"CR60\" class=\"CitationRef\"\u003e60\u003c/span\u003e). Other \u003cem\u003eAcinetobacter\u003c/em\u003e species have been less well studied, although there are numerous reports of isolates of other \u003cem\u003eAcinetobacter\u003c/em\u003e spp. producing various carbapenemases, including metallo-beta-lactamases (\u003cspan citationid=\"CR18\" class=\"CitationRef\"\u003e18\u003c/span\u003e, \u003cspan citationid=\"CR23\" class=\"CitationRef\"\u003e23\u003c/span\u003e, \u003cspan citationid=\"CR24\" class=\"CitationRef\"\u003e24\u003c/span\u003e, \u003cspan citationid=\"CR34\" class=\"CitationRef\"\u003e34\u003c/span\u003e, \u003cspan citationid=\"CR39\" class=\"CitationRef\"\u003e39\u003c/span\u003e, \u003cspan citationid=\"CR43\" class=\"CitationRef\"\u003e43\u003c/span\u003e). Although in our study, only a small number of strains exhibited resistance to carbapenems (0.9% to imipenem, 1.6% to meropenem) or colistin (1.6%), monitoring resistance to these last-resort antibiotics is crucial. The emergence of resistance to those antimicrobials may significantly limit treatment options for severe or life-threatening infections.\u003c/p\u003e \u003cp\u003eSheck et al. demonstrated that colistin resistance was more than three times greater in non-AB strains than in \u003cem\u003eA. baumannii\u003c/em\u003e strains (3.0% vs. 0.8%), with the majority of colistin-resistant isolates identified as \u003cem\u003eA. bereziniae\u003c/em\u003e (\u003cspan citationid=\"CR39\" class=\"CitationRef\"\u003e39\u003c/span\u003e). The latter species was also more resistant to sulbactam, aminoglycosides, trimethoprim\u0026ndash;sulfamethoxazole, and tigecycline than other non-AB species (\u003cspan citationid=\"CR39\" class=\"CitationRef\"\u003e39\u003c/span\u003e). This result is consistent with our findings, with \u003cem\u003eA. bereziniae\u003c/em\u003e showing the highest resistance to carbapenems, all aminoglycosides, and trimethoprim\u0026ndash;sulfamethoxazole. Only the resistance to ampicillin/sulbactam was greater among \u003cem\u003eA. ursingii\u003c/em\u003e strains. Opazo-Capurro's results also indicate the importance of monitoring \u003cem\u003eA. bereziniae\u003c/em\u003e for resistance and its potential to cause difficult-to-treat infections (\u003cspan citationid=\"CR34\" class=\"CitationRef\"\u003e34\u003c/span\u003e). Our colistin-resistant strains were mainly \u003cem\u003eA. ursingii\u003c/em\u003e and \u003cem\u003eA. pittii.\u003c/em\u003e Sykes described a hypervirulent hospital strain resistant to colistin belonging to the species \u003cem\u003eA. courvalinii\u003c/em\u003e (\u003cspan citationid=\"CR61\" class=\"CitationRef\"\u003e61\u003c/span\u003e). Pandrug-resistant \u003cem\u003eA. pittii\u003c/em\u003e has been isolated from a patient with pneumonia in a Chinese hospital (\u003cspan citationid=\"CR36\" class=\"CitationRef\"\u003e36\u003c/span\u003e). In Latin America, \u003cem\u003eAcinetobacter\u003c/em\u003e spp. resistance to imipenem and meropenem varies from 8\u0026ndash;89% (\u003cspan citationid=\"CR62\" class=\"CitationRef\"\u003e62\u003c/span\u003e, \u003cspan citationid=\"CR63\" class=\"CitationRef\"\u003e63\u003c/span\u003e).\u003c/p\u003e"},{"header":"Conclusions","content":"\u003cp\u003eOur study indicated that even if \u003cem\u003eA. baumannii\u003c/em\u003e accounts for 63.1% of isolates from infections between 2021 and 2023, non-\u003cem\u003eA. baumannii\u003c/em\u003e species also play a significant role, particularly in genitourinary and skin infections. Various species, including \u003cem\u003eA. pittii\u003c/em\u003e, have been increasingly associated with hospital-acquired infections, highlighting the need for vigilant monitoring of these pathogens. This study revealed a high resistance rate to ciprofloxacin among isolated strains. Although only a small percentage of strains are resistant to carbapenems or colistin, the emergence of such resistance could severely limit treatment options for critical infections. Early detection and surveillance of resistance patterns are essential to prevent the widespread dissemination of resistant strains. Moreover, ongoing monitoring can inform public health measures and contribute to the development of new therapeutic options. This study also emphasizes the importance of distinguishing between \u003cem\u003eA. baumannii\u003c/em\u003e and non-\u003cem\u003eA. baumannii\u003c/em\u003e species in clinical practice to inform treatment strategies effectively and mitigate the risk of antibiotic resistance spread in healthcare environments.\u003c/p\u003e"},{"header":"Limitations of the study","content":"\u003cp\u003eThe study did not categorize \u003cem\u003eAcinetobacter baumannii\u003c/em\u003e strains on the basis of whether they were isolated from hospitalized patients or outpatients. This makes it difficult to draw clear conclusions about the prevalence and resistance patterns specific to these two patient groups, which may have different infection risks and exposure to antibiotics​\u003c/p\u003e \u003cp\u003eThe authors were also unable to examine the detailed mechanisms of resistance in all the isolated strains because of the observational nature of the study. While resistance patterns have been observed, the underlying molecular mechanisms have not been explored. Understanding these mechanisms would provide deeper insights into how resistance develops and how it can be mitigated​\u003c/p\u003e"},{"header":"Declarations","content":"\u003cp\u003e\u003cstrong\u003eAcknowledgments\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eFunding: This research was funded by the National Science Centre, grant number 2020/39/O/NZ7/00145.\u003c/p\u003e\n\u003cp\u003eInstitutional Review Board Statement: The study was conducted in accordance with the Declaration of Helsinki and approved by the Bioethics Committee of Jagiellonian University (opinion number KBET 1072.6120.274.2021).\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eTransparency declarations\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe authors declare that they have no conflicts of interest.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eAuthor contributions\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eT.K. and M.P. performed the microbiological analyses, analyzed the data, conducted the statistical analyses, prepared the tables and figures, and drafted the manuscript. M.P.-W. and W.P. collected and identified the isolates. A.C. participated in the study design, drafted the manuscript, and supervised the research. All the authors have read and agreed to the published version of the manuscript.\u003c/p\u003e"},{"header":"References","content":"\u003col\u003e\n\u003cli\u003ePeleg AY, Seifert H, Paterson DL. Acinetobacter baumannii: emergence of a successful pathogen. Clin Microbiol Rev [Internet]. 2008 Jul [cited 2024 Dec 1];21(3):538\u0026ndash;82. Available from: https://pubmed.ncbi.nlm.nih.gov/18625687/\u003c/li\u003e\n\u003cli\u003eSkerman VBD, McGowan V, Sneath PHA. Approved lists of bacterial names. Int J Syst Bacteriol. 1980;30(1):225\u0026ndash;420. \u003c/li\u003e\n\u003cli\u003eGenus: Acinetobacter [Internet]. [cited 2024 Dec 18]. Available from: https://lpsn.dsmz.de/genus/acinetobacter\u003c/li\u003e\n\u003cli\u003eXu L, Zhao Y, Li Y, Sun JQ. 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Available from: https://iris.paho.org/handle/10665.2/57313\u003c/li\u003e\n\u003cli\u003eMagnitud y tendencias de la resistencia a los antimicrobianos en Latinoam\u0026eacute;rica. RELAVRA 2014, 2015, 2016. Informe resumido - OPS/OMS | Organizaci\u0026oacute;n Panamericana de la Salud [Internet]. [cited 2024 Dec 18]. Available from: https://www.paho.org/es/documentos/magnitud-tendencias-resistencia-antimicrobianos-latinoamerica-relavra-2014-2015-2016\u003c/li\u003e\n\u003c/ol\u003e"}],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":true,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":true,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":false,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":false,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"Acinetobacter spp., antimicrobial resistance, genitourinary infections, skin and soft tissue infections, colistin","lastPublishedDoi":"10.21203/rs.3.rs-5821427/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-5821427/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003e\u003cstrong\u003eBackground:\u003c/strong\u003e\u003cbr\u003e\n Acinetobacter baumannii (AB) is the most frequently isolated nosocomial pathogen, but severe infections by \u003cem\u003eA. pittii\u003c/em\u003e, \u003cem\u003eA. ursingii\u003c/em\u003e, and \u003cem\u003eA. bereziniae\u003c/em\u003eare increasing. This study investigated the distribution and antibiotic resistance of Acinetobacter spp. strains from various infections.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eMethods:\u003c/strong\u003e\u003cbr\u003e\n Data were collected between 2021–2023 from clinical samples of hospitalized and outpatient individuals in southern Poland. Strains were identified using MALDI-TOF Biotyper, and antibiotic susceptibility was tested with the MIDITECH-Analyzer system. Statistical analyses were conducted using IBM SPSS Statistics.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eResults:\u003c/strong\u003e\u003cbr\u003e\n Among 1507 isolated Acinetobacter strains, 951 (63.1%) were AB, while 556 (36.9%) represented 27 non-AB species. Most isolates (73.6%) came from outpatients, while 26.4% were from hospitalized patients. \u003cem\u003eA. ursingii\u003c/em\u003e (30.2%), \u003cem\u003eA. pittii\u003c/em\u003e (20.6%), and \u003cem\u003eA. junii\u003c/em\u003e(13%) were the most common non-AB species. \u003cem\u003eA. bereziniae\u003c/em\u003e, \u003cem\u003eA. calcoaceticus\u003c/em\u003e, and \u003cem\u003eA. proteolyticus\u003c/em\u003e were more frequently found in hospitalized patients. Non-AB species dominated in/among genital tract infections (87%), whereas AB was more common in invasive infections. Nearly all strains were non-susceptible to ciprofloxacin (98.4%), with lower resistance rates to ampicillin/sulbactam (11.1%), trimethoprim/sulfamethoxazole (5.8%), gentamicin (2.9%), amikacin (2.5%), meropenem (1.6%), and colistin (1.6%). \u003cem\u003eA. bereziniae\u003c/em\u003e showed frequently resistance to carbapenems, aminoglycosides, and trimethoprim/sulfamethoxazole. Colistin resistance was observed in \u003cem\u003eA. ursingii\u003c/em\u003e and \u003cem\u003eA. pittii\u003c/em\u003e.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eConclusions:\u003c/strong\u003e\u003cbr\u003e\n While AB accounted for 63.1% of isolates, non-AB species were common, particularly in genitourinary and skin infections. Emerging hospital-acquired infections by species like \u003cem\u003eA. pittii\u003c/em\u003e underline the need for vigilant monitoring. The high resistance to ciprofloxacin and \u0026nbsp;low but noticeable resistance to carbapenems and colistin highlights the importance of early detection and resistance surveillance to prevent the spread of resistant strains.\u003c/p\u003e","manuscriptTitle":"Distribution and antimicrobial resistance of Acinetobacter spp. isolated from different types of infections from hospitalized patients and outpatients in Poland","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2025-01-15 12:08:21","doi":"10.21203/rs.3.rs-5821427/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"1adfdf2d-77b3-4e9e-95b9-a13a890eb39a","owner":[],"postedDate":"January 15th, 2025","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"posted","subjectAreas":[],"tags":[],"updatedAt":"2025-04-03T19:23:31+00:00","versionOfRecord":[],"versionCreatedAt":"2025-01-15 12:08:21","video":"","vorDoi":"","vorDoiUrl":"","workflowStages":[]},"version":"v1","identity":"rs-5821427","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-5821427","identity":"rs-5821427","version":["v1"]},"buildId":"8U1c8b4HqxoKbykW_rLl7","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}