What is the current status of metastatic prostate cancer in Colombia? A retrospective study based on publicly available state databases

What is the current status of metastatic prostate cancer in Colombia? A retrospective study based on publicly available state databases | Authorea try { document.documentElement.classList.add('js'); } catch (e) { } var _gaq = _gaq || []; _gaq.push(['_setAccount', 'G-8VDV14Y67G']); _gaq.push(['_trackPageview']); (function() { var ga = document.createElement('script'); ga.type = 'text/javascript'; ga.async = true; ga.src = ('https:' == document.location.protocol ? 'https://ssl' : 'http://www') + '.google-analytics.com/ga.js'; var s = document.getElementsByTagName('script')[0]; s.parentNode.insertBefore(ga, s); })(); Skip to main content Preprints Collections Wiley Open Research IET Open Research Ecological Society of Japan All Collections About About Authorea FAQs Contact Us Quick Search anywhere Search for preprint articles, keywords, etc. Search Search ADVANCED SEARCH SCROLL This is a preprint and has not been peer reviewed. Data may be preliminary. 23 June 2025 V1 Latest version Share on What is the current status of metastatic prostate cancer in Colombia? A retrospective study based on publicly available state databases Authors : Santiago Barón Gutiérrez 0000-0002-0080-0062 [email protected] , Nadia Juliana Proaños Jurado , and Rosa-Helena Bustos Authors Info & Affiliations https://doi.org/10.22541/au.175068740.03082425/v1 226 views 118 downloads Contents Abstract Supplementary Material Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Purpose: Metastatic prostate cancer (mPC) imposes a significant clinical and economic burden across Latin America, where pharmacoepidemiological data remain scarce. In Colombia, although prostate cancer is well-documented, data specific to metastatic disease are limited, hindering effective public health planning and equitable resource allocation. This study aims to characterize the epidemiological trends of mPC in Colombia between 2014 and 2023, using integrated national databases to support pharmacoepidemiologic surveillance and inform future therapeutic and policy strategies. Methods: A retrospective, descriptive pharmacoepidemiologic study was conducted using national data from SISPRO (health services utilization), SICC (cancer registry), CAC (health benefit plans), and DANE (vital statistics). Records of men aged 18 and older diagnosed with prostate cancer between 2014 and 2023 were analyzed. Variables assessed included prevalence, incidence, and mortality, as well as demographic characteristics (age, region, ethnicity) and clinical classification (castration-sensitive vs. castration-resistant). Results: A total of 29,182 mPC patients were identified between 2014 and 2023. The annual prevalence increased from 6.5 to 22.3 cases per 100,000 men and incidence nearly doubled. The Caribbean region reported 38.9% of the cases. No substantial differences in age or ethnicity were found compared to general prostate cancer cases. Most cases were castration-sensitive (95%), although castration-resistant cases considerably increased. Conclusion: This study illustrates the growing burden of mPC in Colombia and hightlights the value of leveraging national health information systems for pharmacoepidemiologic insights. Regional disparities underscore the need for targeted policy responses. Improved real-world data integration can enhance monitoring, support drug utilization studies, and inform public health strategies. Supplementary Material File (pds-25-0467-file001.docx) Download 96.25 KB File (pds-25-0467-file002.docx) Download 272.91 KB Information & Authors Information Version history V1 Version 1 23 June 2025 Copyright This work is licensed under a Non Exclusive No Reuse License. Keywords database management systems drug utilization research (dur) health information systems latin america neoplasm metastases prostate cancer real-world data Authors Affiliations Santiago Barón Gutiérrez 0000-0002-0080-0062 [email protected] Clinica Universidad de La Sabana View all articles by this author Nadia Juliana Proaños Jurado Universidad de la Sabana Facultad de Medicina View all articles by this author Rosa-Helena Bustos Clinica Universidad de La Sabana View all articles by this author Metrics & Citations Metrics Article Usage 226 views 118 downloads .FvxKWukQNSOunydq8rnd { width: 100px; } Citations Download citation Santiago Barón Gutiérrez, Nadia Juliana Proaños Jurado, Rosa-Helena Bustos. What is the current status of metastatic prostate cancer in Colombia? A retrospective study based on publicly available state databases. Authorea . 23 June 2025. DOI: https://doi.org/10.22541/au.175068740.03082425/v1 If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click Download. For more information or tips please see 'Downloading to a citation manager' in the Help menu . Format Please select one from the list RIS (ProCite, Reference Manager) EndNote BibTex Medlars RefWorks Direct import Tips for downloading citations document.getElementById('citMgrHelpLink').addEventListener('click', function() { popupHelp(this.href); return false; }); $(".js__slcInclude").on("change", function(e){ if ($(this).val() == 'refworks') $('#direct').prop("checked", false); $('#direct').prop("disabled", ($(this).val() == 'refworks')); }); View Options View options PDF View PDF Figures Tables Media Share Share Share article link Copy Link Copied! Copying failed. 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