Suspected malignant transformation of adenomyosis based on postoperative histopathological diagnosis after laparoscopic hysterectomy: A case report

This case report describes a 45-year-old woman who underwent total laparoscopic hysterectomy for dysmenorrhea after a preoperative diagnosis of uterine adenomyosis, with no abnormal bleeding or endometrial thickening noted preoperatively. Postoperative histopathological examination led to a diagnosis of endometrioid adenocarcinoma, raising concern for malignant transformation after the surgery. The authors note that published literature suggests the malignant transformation rate of uterine adenomyosis is comparable to that of ovarian chocolate cysts, and emphasize that early detection is difficult, with laparoscopic surgery potentially contributing to dissemination of malignant cells. This paper is centrally about adenomyosis — specifically, a suspected malignant transformation to endometrioid adenocarcinoma diagnosed on postoperative pathology after laparoscopic hysterectomy.

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