The puncture model and clinical application of laparoscopic ultrasound-guided liver tumor ablation

The puncture model and clinical application of laparoscopic ultrasound-guided liver tumor ablation | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article The puncture model and clinical application of laparoscopic ultrasound-guided liver tumor ablation Yin Zhang, Yi Wang This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-5927301/v1 This work is licensed under a CC BY 4.0 License Status: Under Review Version 1 posted 4 You are reading this latest preprint version Abstract Laparoscopic ultrasound (LUS) -guided ablation of liver tumors is an important method for the treatment of hepatic neoplasms. This technique involves needle insertion from the lateral side of the ultrasound probe, and selecting the appropriate puncture point presents certain challenges. The right-angle wedge model can effectively demonstrate this puncture process. This study aims to analyze the clinical efficacy of microwave ablation for liver tumors under LUS guidance and to provide a quantitative description of the right-angle wedge model. A total of 13 patients with small liver carcinoma participated in this study. None of these patients experienced significant complications postoperatively, such as bleeding, jaundice, or intestinal injury. Comparisons between preoperative and postoperative day two laboratory indicators revealed a significant increase in alanine aminotransferase levels [32 (15, 62.5) U/L vs. 135 (81, 319.5) U/L], which was statistically significant (P=0.02). Follow-up magnetic resonance imaging (MRI) enhancement one month after surgery indicated that all tumors had been completely ablated. Furthermore, through our research on the right-angle wedge model, we established that by knowing the position of the LUS probe, scanning plane, and angle of needle insertion, it is possible to calculate specific points from which target locations can be reached. In conclusion, LUS-guided liver tumor ablation is conducted safely and effectively under dual visualization provided by both laparoscopy and LUS throughout the procedure. Considering the need for puncture from the side of the LUS probe, this technique requires a solid three-dimensional understanding; based on our models and research, we are able to identify precise puncture points that facilitate rapid completion of both puncture and ablation procedures. Full Text Additional Declarations No competing interests reported. Cite Share Download PDF Status: Under Review Version 1 posted Editorial decision: Revision requested 31 Jan, 2025 Editor assigned by journal 30 Jan, 2025 Submission checks completed at journal 30 Jan, 2025 First submitted to journal 29 Jan, 2025 You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. 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This technique involves needle insertion from the lateral side of the ultrasound probe, and selecting the appropriate puncture point presents certain challenges. The right-angle wedge model can effectively demonstrate this puncture process. This study aims to analyze the clinical efficacy of microwave ablation for liver tumors under LUS guidance and to provide a quantitative description of the right-angle wedge model. A total of 13 patients with small liver carcinoma participated in this study. None of these patients experienced significant complications postoperatively, such as bleeding, jaundice, or intestinal injury. Comparisons between preoperative and postoperative day two laboratory indicators revealed a significant increase in alanine aminotransferase levels [32 (15, 62.5) U/L vs. 135 (81, 319.5) U/L], which was statistically significant (P=0.02). Follow-up magnetic resonance imaging (MRI) enhancement one month after surgery indicated that all tumors had been completely ablated. Furthermore, through our research on the right-angle wedge model, we established that by knowing the position of the LUS probe, scanning plane, and angle of needle insertion, it is possible to calculate specific points from which target locations can be reached. In conclusion, LUS-guided liver tumor ablation is conducted safely and effectively under dual visualization provided by both laparoscopy and LUS throughout the procedure. Considering the need for puncture from the side of the LUS probe, this technique requires a solid three-dimensional understanding; based on our models and research, we are able to identify precise puncture points that facilitate rapid completion of both puncture and ablation procedures.\u003c/p\u003e","manuscriptTitle":"The puncture model and clinical application of laparoscopic ultrasound-guided liver tumor ablation","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2025-02-03 19:03:07","doi":"10.21203/rs.3.rs-5927301/v1","editorialEvents":[{"type":"communityComments","content":0},{"type":"decision","content":"Revision requested","date":"2025-01-31T21:26:05+00:00","index":"","fulltext":""},{"type":"editorAssigned","content":"","date":"2025-01-31T04:33:04+00:00","index":"","fulltext":""},{"type":"checksComplete","content":"","date":"2025-01-30T08:26:50+00:00","index":"","fulltext":""},{"type":"submitted","content":"BMC Cancer","date":"2025-01-30T02:55:33+00:00","index":"","fulltext":""}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"bmc-cancer","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"bcan","sideBox":"Learn more about [BMC Cancer](http://bmccancer.biomedcentral.com/)","snPcode":"","submissionUrl":"https://www.editorialmanager.com/bcan/default.aspx","title":"BMC Cancer","twitterHandle":"BMC_series","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"em","reportingPortfolio":"BMC Series","inReviewEnabled":true,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"67153f86-9e29-4bf6-b731-73138948bce7","owner":[],"postedDate":"February 3rd, 2025","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"under-review","subjectAreas":[],"tags":[],"updatedAt":"2025-02-03T19:03:07+00:00","versionOfRecord":[],"versionCreatedAt":"2025-02-03 19:03:07","video":"","vorDoi":"","vorDoiUrl":"","workflowStages":[]},"version":"v1","identity":"rs-5927301","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-5927301","identity":"rs-5927301","version":["v1"]},"buildId":"8U1c8b4HqxoKbykW_rLl7","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}