Morphological characteristics of endometriosis vesicles.

(A) The percent of implants that developed into vesicles was significantly lower in the antalarmin treated group (n = 20) compared to the vehicle control group (n = 20). (B) The total weight of all vesicles per rat was smaller for the antalarmin treated rats. (C) The average vesicle volume per rat was significantly smaller for the antalarmin treated group compared to the vehicle control group. (D) The average vesicle area per rat was significantly smaller in the antalarmin group compared to the vehicle group. (E) Vesicles that developed were classified by grade based on a scale by size showing that the individual vesicles in the antalarmin treated group tended to be smaller (grade 2) or not develop at all (grade 1). * p< 0.05, ** p< 0.01.