Axis-Space Synchronized Motion Error Estimation for Five-Axis Contour Error Control

Axis-Space Synchronized Motion Error Estimation for Five-Axis Contour Error Control | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Axis-Space Synchronized Motion Error Estimation for Five-Axis Contour Error Control Haijun Li, Jiangang Li This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-8241347/v1 This work is licensed under a CC BY 4.0 License Status: Under Review Version 1 posted 4 You are reading this latest preprint version Abstract This study addresses the modeling and prediction of tracking error in CNC machine tool feed systems by developing a neural network prediction model based on an LSTM-Transformer architecture. To overcome the limitation of conventional data in adequately exciting the dynamic characteristics of servo systems, a featured trajectory construction method is proposed. By incorporating excitation trajectories that encompass various operating conditions—such as startup stopping sequences, direction reversals, and speed variations—the distribution of motion states in the training dataset is systematically enriched, thereby enhancing the model's ability to characterize nonlinear dynamic behaviors. Comparative experiments conducted under the same dataset with conventional LSTM and GRU networks demonstrate that the proposed modeling and featured trajectory design approach significantly reduces the prediction error of the feed system output while maintaining strong generalization performance under complex trajectories. This provides high-precision prior information for subsequent contour error analysis and compensation in CNC machine tools. —Five-axis machine tools Sample generation Tracking error prediction LSTM transformer Full Text Cite Share Download PDF Status: Under Review Version 1 posted Reviewers agreed at journal 13 Dec, 2025 Reviewers invited by journal 10 Dec, 2025 Editor assigned by journal 02 Dec, 2025 First submitted to journal 30 Nov, 2025 You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-8241347","acceptedTermsAndConditions":true,"allowDirectSubmit":false,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":558145355,"identity":"d3e901c3-02ef-46ed-88e5-7fd6f73417c2","order_by":0,"name":"Haijun Li","email":"","orcid":"","institution":"","correspondingAuthor":false,"prefix":"","firstName":"Haijun","middleName":"","lastName":"Li","suffix":""},{"id":558145356,"identity":"6967d9cd-fd50-4cc9-90cc-07880746be39","order_by":1,"name":"Jiangang Li","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAA5klEQVRIiWNgGAWjYBACxmYYix2IPxjY2JGghRnImVGQlkyCfUAtzDwfDjE2EFTYzvzs4ZeaO3YNzMwHH9sYHGBmYD98dAN+h7GZG8sce5bcwMyWbJxjcIePgSct7QZ+LQxm0hJsh5OBrjKTzjF4xswgwWNGQAv7N2mJfyAt/N9/WxgcZmwgrIXHTPJj22E7oC1szAxEaimTZuw7nMDAzGYs2WOQlsxGyC+G/ce3Sf74dtiegb354Ycff2zs+NkPH8OvpQEUHQwMifsPQEXY8CkHAXmQ434wMNgTUjgKRsEoGAUjGAAANsxDk/hMjn0AAAAASUVORK5CYII=","orcid":"","institution":"Harbin institute of technology","correspondingAuthor":true,"prefix":"","firstName":"Jiangang","middleName":"","lastName":"Li","suffix":""}],"badges":[],"createdAt":"2025-11-30 10:25:58","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-8241347/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-8241347/v1","draftVersion":[],"editorialEvents":[],"editorialNote":"","failedWorkflow":false,"files":[{"id":98208669,"identity":"42aa4ad7-fbbe-4969-9b91-93591da6628f","added_by":"auto","created_at":"2025-12-15 09:10:21","extension":"xml","order_by":1,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":8004,"visible":true,"origin":"","legend":"","description":"","filename":"jamtJAMTD2506934.xml","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/9485fc6250bd2ae6dca68772.xml"},{"id":98431213,"identity":"07239741-9f33-4697-abb9-1bb6f15fc81c","added_by":"auto","created_at":"2025-12-17 16:47:16","extension":"xml","order_by":2,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":936,"visible":true,"origin":"","legend":"","description":"","filename":"JAMTD2506934162504.go.xml","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/67f763e05e0952c87b1c664a.xml"},{"id":98432140,"identity":"f9c8b02b-b660-45ad-a698-f5c237c77d2a","added_by":"auto","created_at":"2025-12-17 16:49:05","extension":"xml","order_by":3,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":821,"visible":true,"origin":"","legend":"","description":"","filename":"JAMTD2506934Import.xml","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/66d712881e5de5ad0fde1d51.xml"},{"id":98208651,"identity":"217fd79e-3364-4cbd-a5f9-56b4ccbcf6f9","added_by":"auto","created_at":"2025-12-15 09:10:19","extension":"xml","order_by":4,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":149742,"visible":true,"origin":"","legend":"","description":"","filename":"JAMTD25069340enriched.xml","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/32c28e646f3878a50577b13f.xml"},{"id":98208640,"identity":"158f8b14-83e2-4b2d-83d5-e37ab485adca","added_by":"auto","created_at":"2025-12-15 09:10:15","extension":"jpeg","order_by":5,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":117481,"visible":true,"origin":"","legend":"","description":"","filename":"floatimage1.jpeg","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/430984e9e7bc93e9a407fbbb.jpeg"},{"id":98432874,"identity":"ea83db92-3527-4099-9739-90b8e3336296","added_by":"auto","created_at":"2025-12-17 16:50:04","extension":"png","order_by":6,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":356433,"visible":true,"origin":"","legend":"","description":"","filename":"floatimage10.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/0ba8e9608d8ab27b3fd7fe37.png"},{"id":98208718,"identity":"3c2ba550-d296-4ea0-8ef1-167d3d578da2","added_by":"auto","created_at":"2025-12-15 09:10:24","extension":"png","order_by":7,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":46598,"visible":true,"origin":"","legend":"","description":"","filename":"floatimage11.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/b8389a81eef6fac4c2f60f8a.png"},{"id":98208741,"identity":"48a3d849-4527-4ca0-a1d2-86cd02fc8eb6","added_by":"auto","created_at":"2025-12-15 09:10:26","extension":"png","order_by":8,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":121277,"visible":true,"origin":"","legend":"","description":"","filename":"floatimage12.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/4df92054fed286e498b995d3.png"},{"id":98208668,"identity":"b21caf10-9ec4-403b-ac64-884105c67937","added_by":"auto","created_at":"2025-12-15 09:10:21","extension":"png","order_by":9,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":108251,"visible":true,"origin":"","legend":"","description":"","filename":"floatimage13.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/f10c22f1c7c30ec220e261fd.png"},{"id":98208671,"identity":"5ab6b277-f8d5-49bb-8f49-636506e37373","added_by":"auto","created_at":"2025-12-15 09:10:22","extension":"png","order_by":10,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":33872,"visible":true,"origin":"","legend":"","description":"","filename":"floatimage14.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/bd09de4c209709faf5986f49.png"},{"id":98208832,"identity":"06f52f20-d8ab-4897-ba00-f3979a3603fe","added_by":"auto","created_at":"2025-12-15 09:10:30","extension":"jpeg","order_by":11,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":173832,"visible":true,"origin":"","legend":"","description":"","filename":"floatimage15.jpeg","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/0b63ef779b7576d7ae113901.jpeg"},{"id":98208679,"identity":"b850d33a-53bb-47ff-a71c-93c9278abaaa","added_by":"auto","created_at":"2025-12-15 09:10:22","extension":"jpeg","order_by":12,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":973461,"visible":true,"origin":"","legend":"","description":"","filename":"floatimage16.jpeg","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/ff52a19579c18321de6e3b35.jpeg"},{"id":98431804,"identity":"fad8b380-7cc5-4b72-8138-15ea0e3a691a","added_by":"auto","created_at":"2025-12-17 16:48:24","extension":"png","order_by":13,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":10654,"visible":true,"origin":"","legend":"","description":"","filename":"floatimage2.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/f5e2a3d76f83023e07e56fce.png"},{"id":98430843,"identity":"63aaa6e2-503e-4269-a58d-d71d8ad47d3e","added_by":"auto","created_at":"2025-12-17 16:46:20","extension":"png","order_by":14,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":69281,"visible":true,"origin":"","legend":"","description":"","filename":"floatimage3.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/05fdc285d1d9b8104ef32bf7.png"},{"id":98208683,"identity":"84dd308a-bb93-49a6-81d1-915885c9fccd","added_by":"auto","created_at":"2025-12-15 09:10:22","extension":"png","order_by":15,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":51035,"visible":true,"origin":"","legend":"","description":"","filename":"floatimage4.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/a0e0c1822f9263e1c9a6cb2f.png"},{"id":98208666,"identity":"b18fb42a-a148-4f44-8113-79d69cf08981","added_by":"auto","created_at":"2025-12-15 09:10:21","extension":"png","order_by":16,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":65542,"visible":true,"origin":"","legend":"","description":"","filename":"floatimage5.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/ba77fd381a4b1722d6262947.png"},{"id":98431208,"identity":"8d4f0966-1045-4c18-8281-88628dd35a02","added_by":"auto","created_at":"2025-12-17 16:47:15","extension":"jpeg","order_by":17,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":432410,"visible":true,"origin":"","legend":"","description":"","filename":"floatimage6.jpeg","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/d06cd7b20f8261d37b11ea75.jpeg"},{"id":98208781,"identity":"91eeac5e-110a-4b5d-9bcd-1dbeb3147f7e","added_by":"auto","created_at":"2025-12-15 09:10:28","extension":"png","order_by":18,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":106858,"visible":true,"origin":"","legend":"","description":"","filename":"floatimage7.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/61d24844458120178a2890fe.png"},{"id":98208770,"identity":"c9f94354-afa4-4fce-b64f-4f2bad3d1cd9","added_by":"auto","created_at":"2025-12-15 09:10:27","extension":"png","order_by":19,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":69230,"visible":true,"origin":"","legend":"","description":"","filename":"floatimage8.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/cb27536990e15d52f912ac61.png"},{"id":98208667,"identity":"dc0d0a55-b88c-4a9e-af5c-dcb34b05ebe3","added_by":"auto","created_at":"2025-12-15 09:10:21","extension":"png","order_by":20,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":42992,"visible":true,"origin":"","legend":"","description":"","filename":"floatimage9.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/4e60d67876c993fac3ef4e07.png"},{"id":98433227,"identity":"bf511b1b-6cc5-4e96-8a64-604263b0ab75","added_by":"auto","created_at":"2025-12-17 16:50:28","extension":"wmf","order_by":21,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":740,"visible":true,"origin":"","legend":"","description":"","filename":"image10.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/af82c9ada26fa7a2f8ee06b2.wmf"},{"id":98208641,"identity":"8815004f-a9d2-49e3-93ab-c72593d94795","added_by":"auto","created_at":"2025-12-15 09:10:16","extension":"wmf","order_by":22,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":738,"visible":true,"origin":"","legend":"","description":"","filename":"image101.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/402f2234fdb6d99badfdca3a.wmf"},{"id":98431625,"identity":"bdd863e6-b8fa-4094-a026-937175331fbd","added_by":"auto","created_at":"2025-12-17 16:48:03","extension":"wmf","order_by":23,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1202,"visible":true,"origin":"","legend":"","description":"","filename":"image102.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/309a073cd3ca2d10d2e7fab1.wmf"},{"id":98208752,"identity":"0cf2f6aa-243b-4f84-9451-daa6ae8d7e90","added_by":"auto","created_at":"2025-12-15 09:10:26","extension":"wmf","order_by":24,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":750,"visible":true,"origin":"","legend":"","description":"","filename":"image103.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/9ba3dc1669ca91728cc7c781.wmf"},{"id":98208658,"identity":"19cc4bf5-8430-4070-b9cb-bd9596a095f5","added_by":"auto","created_at":"2025-12-15 09:10:20","extension":"wmf","order_by":25,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":738,"visible":true,"origin":"","legend":"","description":"","filename":"image104.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/cea64fba5045e74bbad23e18.wmf"},{"id":98208735,"identity":"48423645-dd3d-4c9c-a704-37320f364c71","added_by":"auto","created_at":"2025-12-15 09:10:26","extension":"wmf","order_by":26,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":876,"visible":true,"origin":"","legend":"","description":"","filename":"image105.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/03245a7eeae63618df41765a.wmf"},{"id":98208644,"identity":"1e3286eb-4e12-4ce2-8ffa-f4b8d4a1170a","added_by":"auto","created_at":"2025-12-15 09:10:17","extension":"wmf","order_by":27,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":876,"visible":true,"origin":"","legend":"","description":"","filename":"image106.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/1464fd1a66e110b9daa0e0a3.wmf"},{"id":98432879,"identity":"46152fc2-5d7f-477a-8880-1da02737c963","added_by":"auto","created_at":"2025-12-17 16:50:05","extension":"wmf","order_by":28,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1368,"visible":true,"origin":"","legend":"","description":"","filename":"image107.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/668559011e9bafb355567dd8.wmf"},{"id":98431396,"identity":"8ce46afd-733d-4ee0-8876-1ba7f1910734","added_by":"auto","created_at":"2025-12-17 16:47:37","extension":"wmf","order_by":29,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":876,"visible":true,"origin":"","legend":"","description":"","filename":"image108.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/7955f207ab82129f3a10cbc1.wmf"},{"id":98208754,"identity":"77923292-52f2-4457-a5b1-8eac44febf5f","added_by":"auto","created_at":"2025-12-15 09:10:26","extension":"wmf","order_by":30,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":2104,"visible":true,"origin":"","legend":"","description":"","filename":"image109.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/d62096cd8f22c1bbbf94d769.wmf"},{"id":98208650,"identity":"84659886-364a-4186-a60c-20eff93e9edf","added_by":"auto","created_at":"2025-12-15 09:10:19","extension":"wmf","order_by":31,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1254,"visible":true,"origin":"","legend":"","description":"","filename":"image11.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/a1d5267d04bb7569ef831ed2.wmf"},{"id":98208647,"identity":"da7adbf1-2691-42bf-81eb-620528c9283e","added_by":"auto","created_at":"2025-12-15 09:10:18","extension":"wmf","order_by":32,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":874,"visible":true,"origin":"","legend":"","description":"","filename":"image110.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/e635f79a1eda6781a2e20bcd.wmf"},{"id":98431974,"identity":"79e47662-0975-498b-9b94-4c69177e78c3","added_by":"auto","created_at":"2025-12-17 16:48:43","extension":"wmf","order_by":33,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1720,"visible":true,"origin":"","legend":"","description":"","filename":"image111.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/eec8475ad58f17f95ae432e7.wmf"},{"id":98433214,"identity":"680c3a08-2874-428a-b4f2-9311f8f186bd","added_by":"auto","created_at":"2025-12-17 16:50:28","extension":"wmf","order_by":34,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":4596,"visible":true,"origin":"","legend":"","description":"","filename":"image12.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/3324bf0b18b91644d9ef2c8b.wmf"},{"id":98208649,"identity":"25480ab4-34b2-40bc-835c-1d7c050cdc18","added_by":"auto","created_at":"2025-12-15 09:10:18","extension":"wmf","order_by":35,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":842,"visible":true,"origin":"","legend":"","description":"","filename":"image13.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/eddd19e3a5f20ccf1fd9ab55.wmf"},{"id":98433262,"identity":"269d292c-8950-4e23-8ee5-f87167dc5030","added_by":"auto","created_at":"2025-12-17 16:50:31","extension":"wmf","order_by":36,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1744,"visible":true,"origin":"","legend":"","description":"","filename":"image14.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/09f29fae71df6b49cfc57245.wmf"},{"id":98208790,"identity":"2c9f1968-18cb-44a0-82cd-d6f45959a94c","added_by":"auto","created_at":"2025-12-15 09:10:28","extension":"wmf","order_by":37,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1744,"visible":true,"origin":"","legend":"","description":"","filename":"image15.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/09dfb63bd472c636fcbdc1bf.wmf"},{"id":98431232,"identity":"adcea66e-37fc-4416-bac7-3231c2cb21dd","added_by":"auto","created_at":"2025-12-17 16:47:19","extension":"wmf","order_by":38,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":870,"visible":true,"origin":"","legend":"","description":"","filename":"image19.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/09798e3ddf4f14f69cfa6170.wmf"},{"id":98432688,"identity":"538addb2-4700-4807-be8d-96262f3e91a7","added_by":"auto","created_at":"2025-12-17 16:49:48","extension":"wmf","order_by":39,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":868,"visible":true,"origin":"","legend":"","description":"","filename":"image20.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/5daf238590d910c19e690955.wmf"},{"id":98432826,"identity":"c2b31635-3864-4b1a-8f46-149f98953d15","added_by":"auto","created_at":"2025-12-17 16:50:02","extension":"wmf","order_by":40,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":626,"visible":true,"origin":"","legend":"","description":"","filename":"image21.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/cf66af5aadc150750eaf48c3.wmf"},{"id":98433029,"identity":"2c1a5785-6fbc-43ed-8d40-bc02109d1df9","added_by":"auto","created_at":"2025-12-17 16:50:12","extension":"wmf","order_by":41,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":624,"visible":true,"origin":"","legend":"","description":"","filename":"image22.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/33411bb2427fa4e4e4816db3.wmf"},{"id":98433261,"identity":"673f9281-136b-4749-8f62-43c5d0912184","added_by":"auto","created_at":"2025-12-17 16:50:31","extension":"wmf","order_by":42,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1214,"visible":true,"origin":"","legend":"","description":"","filename":"image23.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/df47df3e7ed2eb2d7be150dd.wmf"},{"id":98433375,"identity":"aa3c8262-9a54-4151-8446-7121b8dbdd8e","added_by":"auto","created_at":"2025-12-17 16:50:41","extension":"wmf","order_by":43,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":2640,"visible":true,"origin":"","legend":"","description":"","filename":"image24.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/a9171c302d3457c6d76928dd.wmf"},{"id":98431840,"identity":"d882868f-17dc-4145-ba0a-fa1e03e26b02","added_by":"auto","created_at":"2025-12-17 16:48:28","extension":"wmf","order_by":44,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1150,"visible":true,"origin":"","legend":"","description":"","filename":"image25.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/9f3a8d36a3d8bd865b8546ae.wmf"},{"id":98208782,"identity":"e45cb6d1-3cce-4115-b961-032cf2f3d071","added_by":"auto","created_at":"2025-12-15 09:10:28","extension":"wmf","order_by":45,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1150,"visible":true,"origin":"","legend":"","description":"","filename":"image26.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/7dc9f2797b53cbf26503696c.wmf"},{"id":98208670,"identity":"ed016d05-147f-4e14-b95c-6d5a742169dd","added_by":"auto","created_at":"2025-12-15 09:10:22","extension":"wmf","order_by":46,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1150,"visible":true,"origin":"","legend":"","description":"","filename":"image27.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/842599c35f51bbbe5176b1a9.wmf"},{"id":98431745,"identity":"f11c974a-164a-4718-81e8-b07aa7f97dbd","added_by":"auto","created_at":"2025-12-17 16:48:17","extension":"wmf","order_by":47,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1150,"visible":true,"origin":"","legend":"","description":"","filename":"image28.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/34f449ca8eed128e8e691092.wmf"},{"id":98431959,"identity":"5596fc35-b6e1-48c6-8f48-cfaadcc79cc5","added_by":"auto","created_at":"2025-12-17 16:48:42","extension":"wmf","order_by":48,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1130,"visible":true,"origin":"","legend":"","description":"","filename":"image29.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/157e1b40a774495a5fa40615.wmf"},{"id":98431460,"identity":"10c27774-ff8b-4468-8204-ec35a577a5dc","added_by":"auto","created_at":"2025-12-17 16:47:43","extension":"wmf","order_by":49,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":740,"visible":true,"origin":"","legend":"","description":"","filename":"image3.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/a4f45b2255ed81b945bc611e.wmf"},{"id":98432413,"identity":"d5ae6e45-8f54-4486-9c2c-249fe3382791","added_by":"auto","created_at":"2025-12-17 16:49:31","extension":"wmf","order_by":50,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1130,"visible":true,"origin":"","legend":"","description":"","filename":"image30.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/34116507d14d2f4c883c33e0.wmf"},{"id":98432366,"identity":"e05f8125-b238-4e6a-96e4-35d0a90a4d95","added_by":"auto","created_at":"2025-12-17 16:49:28","extension":"wmf","order_by":51,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":860,"visible":true,"origin":"","legend":"","description":"","filename":"image31.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/74c0eb524c20648da880c54f.wmf"},{"id":98431775,"identity":"6dc2bbb2-2043-4c47-a39b-3ea073041ff5","added_by":"auto","created_at":"2025-12-17 16:48:20","extension":"wmf","order_by":52,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":860,"visible":true,"origin":"","legend":"","description":"","filename":"image32.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/d0dc7afdeabadcb1fdaaa6a6.wmf"},{"id":98208646,"identity":"a13f7a36-eb3c-4264-b25a-f78e0b72b809","added_by":"auto","created_at":"2025-12-15 09:10:17","extension":"wmf","order_by":53,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1796,"visible":true,"origin":"","legend":"","description":"","filename":"image33.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/fae566585fe8f6f8439ad020.wmf"},{"id":98430683,"identity":"6a94703c-79e2-41c4-9f7d-df40e63aae64","added_by":"auto","created_at":"2025-12-17 16:46:02","extension":"wmf","order_by":54,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":860,"visible":true,"origin":"","legend":"","description":"","filename":"image34.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/1d466dc3d5f21ff1881a99b0.wmf"},{"id":98208675,"identity":"bd34645c-5ff1-4cae-a43c-989eda1d2b42","added_by":"auto","created_at":"2025-12-15 09:10:22","extension":"wmf","order_by":55,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":946,"visible":true,"origin":"","legend":"","description":"","filename":"image35.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/3156eec954481cc82729f730.wmf"},{"id":98208693,"identity":"ca776c84-7b7a-468b-9e98-3fad846963d8","added_by":"auto","created_at":"2025-12-15 09:10:23","extension":"wmf","order_by":56,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":870,"visible":true,"origin":"","legend":"","description":"","filename":"image36.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/2c0a6d2934787f1211c537f2.wmf"},{"id":98432989,"identity":"941384e7-12d1-409f-b169-412fdeb43cb1","added_by":"auto","created_at":"2025-12-17 16:50:11","extension":"wmf","order_by":57,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":7132,"visible":true,"origin":"","legend":"","description":"","filename":"image37.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/56c59cbf3127a70f3db288e5.wmf"},{"id":98208642,"identity":"af780a6c-f1db-4f60-8fb3-eb5630442139","added_by":"auto","created_at":"2025-12-15 09:10:16","extension":"wmf","order_by":58,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":960,"visible":true,"origin":"","legend":"","description":"","filename":"image38.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/480c7caf380d92f8c2e3672a.wmf"},{"id":98431864,"identity":"1c8e052a-c54e-4203-b6f7-8c99afbd9e6f","added_by":"auto","created_at":"2025-12-17 16:48:29","extension":"wmf","order_by":59,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":624,"visible":true,"origin":"","legend":"","description":"","filename":"image39.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/d8d7ea497d2590160d178f12.wmf"},{"id":98432174,"identity":"a0de4b85-134a-4d55-8701-9cbcbd8432a2","added_by":"auto","created_at":"2025-12-17 16:49:10","extension":"wmf","order_by":60,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":740,"visible":true,"origin":"","legend":"","description":"","filename":"image4.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/108bc4e2ff4d837b4ff86133.wmf"},{"id":98431282,"identity":"c9595c00-f4a2-4415-9b95-390e08956fd1","added_by":"auto","created_at":"2025-12-17 16:47:27","extension":"wmf","order_by":61,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1440,"visible":true,"origin":"","legend":"","description":"","filename":"image40.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/f72cfc7b3a5d2af0c337c3b7.wmf"},{"id":98432880,"identity":"220f5947-a3e1-4b73-b966-42d59521181c","added_by":"auto","created_at":"2025-12-17 16:50:05","extension":"wmf","order_by":62,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":624,"visible":true,"origin":"","legend":"","description":"","filename":"image42.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/7e1e636576bf41faeb00b945.wmf"},{"id":98432955,"identity":"0f6bb0a8-645f-4026-ba2e-bc0c4b1c02f9","added_by":"auto","created_at":"2025-12-17 16:50:08","extension":"wmf","order_by":63,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1414,"visible":true,"origin":"","legend":"","description":"","filename":"image43.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/6c2360308565ada8f5932e01.wmf"},{"id":98208761,"identity":"b5156830-7b6a-462d-a8a6-5ad19fbcc552","added_by":"auto","created_at":"2025-12-15 09:10:27","extension":"wmf","order_by":64,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":742,"visible":true,"origin":"","legend":"","description":"","filename":"image44.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/2b0f8ca58ebd0ee6bc73b15a.wmf"},{"id":98208771,"identity":"d0a2395e-a8b9-4bd0-bb93-8be5ad4c6a54","added_by":"auto","created_at":"2025-12-15 09:10:27","extension":"wmf","order_by":65,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1894,"visible":true,"origin":"","legend":"","description":"","filename":"image45.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/339bf1495fdd4f8fda378ec9.wmf"},{"id":98433161,"identity":"cf938bac-acdf-4469-ad15-d359516206e5","added_by":"auto","created_at":"2025-12-17 16:50:21","extension":"wmf","order_by":66,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1166,"visible":true,"origin":"","legend":"","description":"","filename":"image46.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/dea49bfe841d3edcd50ffd5e.wmf"},{"id":98433069,"identity":"8a59b83a-f31d-4a22-9bd7-7e6aaed2c663","added_by":"auto","created_at":"2025-12-17 16:50:13","extension":"wmf","order_by":67,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":740,"visible":true,"origin":"","legend":"","description":"","filename":"image47.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/80b09b8dd6b978b69fae311f.wmf"},{"id":98431231,"identity":"460a812f-cd17-4503-8183-fece074f01e8","added_by":"auto","created_at":"2025-12-17 16:47:19","extension":"wmf","order_by":68,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":756,"visible":true,"origin":"","legend":"","description":"","filename":"image48.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/a9006e6e2d1dfb503699b4bb.wmf"},{"id":98432482,"identity":"2a67b263-8b56-48f4-98b9-17842cee80c2","added_by":"auto","created_at":"2025-12-17 16:49:36","extension":"wmf","order_by":69,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":756,"visible":true,"origin":"","legend":"","description":"","filename":"image49.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/0ecf667280a3313476847ee9.wmf"},{"id":98208786,"identity":"2536dcfd-8b2e-4ff6-8c85-ca58757f00df","added_by":"auto","created_at":"2025-12-15 09:10:28","extension":"wmf","order_by":70,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":890,"visible":true,"origin":"","legend":"","description":"","filename":"image5.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/65e09300733050219b1ac700.wmf"},{"id":98432717,"identity":"006b3803-32f7-4010-8ae3-04da63f1ff0f","added_by":"auto","created_at":"2025-12-17 16:49:50","extension":"wmf","order_by":71,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":884,"visible":true,"origin":"","legend":"","description":"","filename":"image50.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/112a51572dfc20000dd05581.wmf"},{"id":98432843,"identity":"14406ba3-ea8f-422a-a02a-25c06ca5266d","added_by":"auto","created_at":"2025-12-17 16:50:02","extension":"wmf","order_by":72,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":742,"visible":true,"origin":"","legend":"","description":"","filename":"image51.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/48b96d753805942d6dfac6d4.wmf"},{"id":98208812,"identity":"18f72ccb-0ae2-424f-b66d-0608fa4a7feb","added_by":"auto","created_at":"2025-12-15 09:10:29","extension":"wmf","order_by":73,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":922,"visible":true,"origin":"","legend":"","description":"","filename":"image52.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/b16af23ecf327430bd2f24a4.wmf"},{"id":98208722,"identity":"032c23ff-f1e4-4412-ae98-50568ba87121","added_by":"auto","created_at":"2025-12-15 09:10:25","extension":"wmf","order_by":74,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":912,"visible":true,"origin":"","legend":"","description":"","filename":"image53.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/26985c005c0f69770af3af27.wmf"},{"id":98208795,"identity":"a1f8d9cc-361d-4a29-a2cd-6508bf961cc5","added_by":"auto","created_at":"2025-12-15 09:10:28","extension":"wmf","order_by":75,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":2458,"visible":true,"origin":"","legend":"","description":"","filename":"image54.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/ad84fd265e38f9eff51e49c2.wmf"},{"id":98208763,"identity":"2deae871-56dc-4243-82c6-52798ac0cde9","added_by":"auto","created_at":"2025-12-15 09:10:27","extension":"wmf","order_by":76,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":2070,"visible":true,"origin":"","legend":"","description":"","filename":"image55.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/59f8e5127044f2dc443e9b04.wmf"},{"id":98208710,"identity":"462c9438-7072-4d8a-8851-8d5a2a39a6b0","added_by":"auto","created_at":"2025-12-15 09:10:24","extension":"wmf","order_by":77,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1102,"visible":true,"origin":"","legend":"","description":"","filename":"image56.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/79e1b2c14c0723b8e4373832.wmf"},{"id":98431220,"identity":"1ada6695-e630-4b6b-bf12-aa08a55a357d","added_by":"auto","created_at":"2025-12-17 16:47:18","extension":"wmf","order_by":78,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1074,"visible":true,"origin":"","legend":"","description":"","filename":"image57.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/41b6cf478a94d68ab01871b5.wmf"},{"id":98208823,"identity":"1818e669-1416-4fba-ac2f-481d977e5a4b","added_by":"auto","created_at":"2025-12-15 09:10:30","extension":"wmf","order_by":79,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1058,"visible":true,"origin":"","legend":"","description":"","filename":"image58.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/dffe0dc62dea67adef98eb85.wmf"},{"id":98208645,"identity":"98b50f0f-c9bb-463f-a310-a305d61458a7","added_by":"auto","created_at":"2025-12-15 09:10:17","extension":"wmf","order_by":80,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":882,"visible":true,"origin":"","legend":"","description":"","filename":"image6.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/ab30c9aab292beefeb25bbd9.wmf"},{"id":98208819,"identity":"227303e8-1b21-4d83-97c5-1df8138b5280","added_by":"auto","created_at":"2025-12-15 09:10:30","extension":"wmf","order_by":81,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1516,"visible":true,"origin":"","legend":"","description":"","filename":"image61.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/ff467508887c6d97544a26ea.wmf"},{"id":98432933,"identity":"ccb2f4ad-36ca-4154-a4bf-e19d6c8c74cc","added_by":"auto","created_at":"2025-12-17 16:50:07","extension":"wmf","order_by":82,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":624,"visible":true,"origin":"","legend":"","description":"","filename":"image62.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/14c824419243254b8b1162ba.wmf"},{"id":98208814,"identity":"11260214-8724-4074-baaf-791365bb6497","added_by":"auto","created_at":"2025-12-15 09:10:29","extension":"wmf","order_by":83,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":740,"visible":true,"origin":"","legend":"","description":"","filename":"image63.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/f711335fa35cfaa49e6b3483.wmf"},{"id":98208678,"identity":"52433e53-58bb-476a-8660-639f7b50956a","added_by":"auto","created_at":"2025-12-15 09:10:22","extension":"wmf","order_by":84,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":952,"visible":true,"origin":"","legend":"","description":"","filename":"image64.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/b010f90e865ce2b434bfe786.wmf"},{"id":98432179,"identity":"4f2feb5c-c353-4371-9604-ff0266096e86","added_by":"auto","created_at":"2025-12-17 16:49:10","extension":"wmf","order_by":85,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":740,"visible":true,"origin":"","legend":"","description":"","filename":"image65.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/09f5e1af15c7158308a2760c.wmf"},{"id":98208783,"identity":"7d651a30-ee08-4b31-aedd-4615faabae30","added_by":"auto","created_at":"2025-12-15 09:10:28","extension":"wmf","order_by":86,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":842,"visible":true,"origin":"","legend":"","description":"","filename":"image66.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/7b15821cd889e630791e3260.wmf"},{"id":98433304,"identity":"57305e89-354c-4a2e-884b-52deaedcb1d8","added_by":"auto","created_at":"2025-12-17 16:50:35","extension":"wmf","order_by":87,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1244,"visible":true,"origin":"","legend":"","description":"","filename":"image67.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/2d86740b55b36f51b4992f01.wmf"},{"id":98432584,"identity":"ec2d90aa-02cc-468e-9796-054a0333f575","added_by":"auto","created_at":"2025-12-17 16:49:43","extension":"wmf","order_by":88,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":740,"visible":true,"origin":"","legend":"","description":"","filename":"image68.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/a33b13613b8914b3ce6cd4cc.wmf"},{"id":98432183,"identity":"642025f9-5dc6-4e4e-b11f-70c3b00c896a","added_by":"auto","created_at":"2025-12-17 16:49:10","extension":"wmf","order_by":89,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":740,"visible":true,"origin":"","legend":"","description":"","filename":"image69.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/3517100048bb4c3f461cbc7a.wmf"},{"id":98431667,"identity":"bd4e24a2-f608-4907-be06-a133c6098d11","added_by":"auto","created_at":"2025-12-17 16:48:07","extension":"wmf","order_by":90,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":952,"visible":true,"origin":"","legend":"","description":"","filename":"image70.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/fab7bb244c9368adf9b666e3.wmf"},{"id":98208793,"identity":"458d1608-f23e-492e-809e-a8b2b88abd76","added_by":"auto","created_at":"2025-12-15 09:10:28","extension":"wmf","order_by":91,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":842,"visible":true,"origin":"","legend":"","description":"","filename":"image71.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/ff058db60bc14ca9efa70f2c.wmf"},{"id":98432336,"identity":"7ec2e8f9-4a07-4606-944d-4cd7eaac3d89","added_by":"auto","created_at":"2025-12-17 16:49:25","extension":"wmf","order_by":92,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1280,"visible":true,"origin":"","legend":"","description":"","filename":"image72.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/ced1e02b85cf8bb54ff75cb5.wmf"},{"id":98431398,"identity":"a026a1e1-1355-45c6-912e-5ac991eac9ee","added_by":"auto","created_at":"2025-12-17 16:47:38","extension":"wmf","order_by":93,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1256,"visible":true,"origin":"","legend":"","description":"","filename":"image73.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/e393480337982441d99da114.wmf"},{"id":98431724,"identity":"60b0dae5-df66-44df-a743-ede2ae987a78","added_by":"auto","created_at":"2025-12-17 16:48:13","extension":"wmf","order_by":94,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1256,"visible":true,"origin":"","legend":"","description":"","filename":"image74.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/fd9efcd9abeb88465e5ab4cb.wmf"},{"id":98431357,"identity":"9fde6d23-4cd1-46d7-8c55-0400c365c3ab","added_by":"auto","created_at":"2025-12-17 16:47:34","extension":"wmf","order_by":95,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1682,"visible":true,"origin":"","legend":"","description":"","filename":"image75.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/8d2b43a7d10ac47c94b573fe.wmf"},{"id":98208681,"identity":"be9927e9-aeb3-47e0-adb8-53659ba0d8e7","added_by":"auto","created_at":"2025-12-15 09:10:22","extension":"wmf","order_by":96,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1796,"visible":true,"origin":"","legend":"","description":"","filename":"image76.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/7f0ad8e5e5a473d1f7258254.wmf"},{"id":98432144,"identity":"59f9c487-cf06-45b0-86f3-25832da957c7","added_by":"auto","created_at":"2025-12-17 16:49:06","extension":"wmf","order_by":97,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":624,"visible":true,"origin":"","legend":"","description":"","filename":"image77.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/ffe9b42a307e9f94cb8a990e.wmf"},{"id":98208728,"identity":"3db1cb82-4486-4501-b3c4-9f21600d5752","added_by":"auto","created_at":"2025-12-15 09:10:25","extension":"wmf","order_by":98,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":624,"visible":true,"origin":"","legend":"","description":"","filename":"image78.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/e46d07bc79b367cf0bd5deba.wmf"},{"id":98208685,"identity":"8b74c881-06f0-420f-87e4-ba092cb21158","added_by":"auto","created_at":"2025-12-15 09:10:22","extension":"wmf","order_by":99,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":882,"visible":true,"origin":"","legend":"","description":"","filename":"image79.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/17fb6ec4328bafe0c269e39a.wmf"},{"id":98432628,"identity":"b57fe2b5-65f2-4a41-8dfa-62a44ab71a26","added_by":"auto","created_at":"2025-12-17 16:49:45","extension":"wmf","order_by":100,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":4308,"visible":true,"origin":"","legend":"","description":"","filename":"image8.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/9941fc2b6181fe673f86bfa9.wmf"},{"id":98431940,"identity":"063d07eb-7f54-4774-a01f-662bb6ebbd3a","added_by":"auto","created_at":"2025-12-17 16:48:40","extension":"wmf","order_by":101,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":624,"visible":true,"origin":"","legend":"","description":"","filename":"image80.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/cbd73d8a6be2dacc70d393c3.wmf"},{"id":98431415,"identity":"3322c193-1a17-4ab5-832a-772250067f42","added_by":"auto","created_at":"2025-12-17 16:47:39","extension":"wmf","order_by":102,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":752,"visible":true,"origin":"","legend":"","description":"","filename":"image81.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/82ec0b86608e2f33dde712bb.wmf"},{"id":98208661,"identity":"e40a626f-eb23-460b-97dd-8ddc2685cb8b","added_by":"auto","created_at":"2025-12-15 09:10:20","extension":"wmf","order_by":103,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":624,"visible":true,"origin":"","legend":"","description":"","filename":"image82.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/9c6addf3280a10ab3b20c9cc.wmf"},{"id":98208655,"identity":"c5c3ace3-18e2-4cdc-a98b-fc80ca464a50","added_by":"auto","created_at":"2025-12-15 09:10:20","extension":"wmf","order_by":104,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":624,"visible":true,"origin":"","legend":"","description":"","filename":"image83.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/f09978c0fc7f8f5b15ceda78.wmf"},{"id":98208865,"identity":"81120dd8-19b9-4ec6-941d-29563e5b0b49","added_by":"auto","created_at":"2025-12-15 09:10:33","extension":"wmf","order_by":105,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":748,"visible":true,"origin":"","legend":"","description":"","filename":"image84.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/98d05cafa67c41b3c1a038c8.wmf"},{"id":98433079,"identity":"b5645723-a9ca-44fd-a7c2-0bff237a10dd","added_by":"auto","created_at":"2025-12-17 16:50:14","extension":"wmf","order_by":106,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1948,"visible":true,"origin":"","legend":"","description":"","filename":"image85.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/d1ec7357dfab73d7d9cb5521.wmf"},{"id":98208803,"identity":"31e7c95f-075a-44b0-bed1-14e1bc12d69f","added_by":"auto","created_at":"2025-12-15 09:10:29","extension":"wmf","order_by":107,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1132,"visible":true,"origin":"","legend":"","description":"","filename":"image86.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/f454aec1313b5a9633bd8cf0.wmf"},{"id":98431822,"identity":"4adc8da4-cca9-46e2-9794-46806a5f9743","added_by":"auto","created_at":"2025-12-17 16:48:24","extension":"wmf","order_by":108,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1514,"visible":true,"origin":"","legend":"","description":"","filename":"image87.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/2bad7f1486212a4f68aeca90.wmf"},{"id":98208747,"identity":"a3cff43b-a579-403f-919e-f255ceb42aa8","added_by":"auto","created_at":"2025-12-15 09:10:26","extension":"wmf","order_by":109,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":624,"visible":true,"origin":"","legend":"","description":"","filename":"image88.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/e50b96e98821f70bac328686.wmf"},{"id":98208856,"identity":"f9b46e84-491b-4618-9c34-fc033712640f","added_by":"auto","created_at":"2025-12-15 09:10:32","extension":"wmf","order_by":110,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":624,"visible":true,"origin":"","legend":"","description":"","filename":"image89.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/0123fc8506931ac17558597e.wmf"},{"id":98432145,"identity":"525f99ad-a280-40ca-b83a-4d60d11118e4","added_by":"auto","created_at":"2025-12-17 16:49:06","extension":"wmf","order_by":111,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1098,"visible":true,"origin":"","legend":"","description":"","filename":"image9.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/4b792782ff5e40e8bfebc6d7.wmf"},{"id":98431806,"identity":"0febc784-ee7b-4e84-b8ee-ce966cda4aa9","added_by":"auto","created_at":"2025-12-17 16:48:24","extension":"wmf","order_by":112,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":740,"visible":true,"origin":"","legend":"","description":"","filename":"image90.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/e9a1c87356d52a3f15a0d9f8.wmf"},{"id":98432598,"identity":"a795f61d-46c8-4a8a-a2a6-51e85485992f","added_by":"auto","created_at":"2025-12-17 16:49:44","extension":"wmf","order_by":113,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":624,"visible":true,"origin":"","legend":"","description":"","filename":"image91.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/f52a6bbd553b8ebe6cee968c.wmf"},{"id":98208725,"identity":"bc87ef5b-8a29-4c4f-9800-3b5d57f1e7f9","added_by":"auto","created_at":"2025-12-15 09:10:25","extension":"wmf","order_by":114,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1558,"visible":true,"origin":"","legend":"","description":"","filename":"image92.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/d7e00e912cfc726b64205de8.wmf"},{"id":98432122,"identity":"5a5b08a9-5380-41f6-b547-5b6f46a7379f","added_by":"auto","created_at":"2025-12-17 16:49:02","extension":"wmf","order_by":115,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1106,"visible":true,"origin":"","legend":"","description":"","filename":"image93.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/6c3ddc47afbf1e4b3d45e5e6.wmf"},{"id":98208700,"identity":"5b315bc8-dd99-44f3-a4f8-8f177dde7ce0","added_by":"auto","created_at":"2025-12-15 09:10:23","extension":"wmf","order_by":116,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1532,"visible":true,"origin":"","legend":"","description":"","filename":"image94.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/2e81191fd8e43e4c44cd7865.wmf"},{"id":98433116,"identity":"230ef476-90b8-4bd1-940a-e3905b5bddfb","added_by":"auto","created_at":"2025-12-17 16:50:17","extension":"wmf","order_by":117,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":874,"visible":true,"origin":"","legend":"","description":"","filename":"image97.wmf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/3400aa07e3b3398f8e6af404.wmf"},{"id":98208663,"identity":"497c265f-f8c8-4bbb-a673-e7a21b498d50","added_by":"auto","created_at":"2025-12-15 09:10:21","extension":"png","order_by":118,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":44493,"visible":true,"origin":"","legend":"","description":"","filename":"Onlinefloatimage1.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/65da33fedf726ec466d77d81.png"},{"id":98208708,"identity":"6c6dc66a-bb56-4f89-920a-bc17482db5c7","added_by":"auto","created_at":"2025-12-15 09:10:24","extension":"png","order_by":119,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":36108,"visible":true,"origin":"","legend":"","description":"","filename":"Onlinefloatimage10.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/1f998f560c84fbf1b772e5ba.png"},{"id":98623135,"identity":"5e042719-885e-4b92-a6e3-e7aca3a2ab09","added_by":"auto","created_at":"2025-12-19 17:04:47","extension":"png","order_by":120,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":31512,"visible":true,"origin":"","legend":"","description":"","filename":"Onlinefloatimage11.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/f12dbd13485c1301a2590dd9.png"},{"id":98431981,"identity":"457cc5e8-abdb-4720-837f-cc925aac7b7f","added_by":"auto","created_at":"2025-12-17 16:48:43","extension":"png","order_by":121,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":27292,"visible":true,"origin":"","legend":"","description":"","filename":"Onlinefloatimage12.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/a24f6050bb24d97e3d560ae4.png"},{"id":98208704,"identity":"75166085-06e6-440e-857a-e8ffa660b11a","added_by":"auto","created_at":"2025-12-15 09:10:24","extension":"png","order_by":122,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":61740,"visible":true,"origin":"","legend":"","description":"","filename":"Onlinefloatimage13.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/7a4946e4aa4e473de1371299.png"},{"id":98208834,"identity":"7adc6423-2817-4999-a26b-ed63ee496cca","added_by":"auto","created_at":"2025-12-15 09:10:30","extension":"png","order_by":123,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":21658,"visible":true,"origin":"","legend":"","description":"","filename":"Onlinefloatimage14.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/2a65cf47fac3bdb160f5206a.png"},{"id":98433070,"identity":"90b10da9-69fc-4073-b6d9-e100d9665a1f","added_by":"auto","created_at":"2025-12-17 16:50:13","extension":"png","order_by":124,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":27281,"visible":true,"origin":"","legend":"","description":"","filename":"Onlinefloatimage15.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/e8fa166e385f643f46f14c92.png"},{"id":98208687,"identity":"74d42eee-8afe-42f3-a448-ce6a8638de32","added_by":"auto","created_at":"2025-12-15 09:10:23","extension":"png","order_by":125,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":210395,"visible":true,"origin":"","legend":"","description":"","filename":"Onlinefloatimage16.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/9f4964aeaa2487bcaf565ae1.png"},{"id":98432678,"identity":"ebb9ed9e-8fa0-4223-b176-2c5e28ca16e6","added_by":"auto","created_at":"2025-12-17 16:49:47","extension":"png","order_by":126,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":4118,"visible":true,"origin":"","legend":"","description":"","filename":"Onlinefloatimage2.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/761bbf616542904a6e1e6667.png"},{"id":98208653,"identity":"b19e4e45-b663-4697-b7cd-39053181f981","added_by":"auto","created_at":"2025-12-15 09:10:20","extension":"png","order_by":127,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":46871,"visible":true,"origin":"","legend":"","description":"","filename":"Onlinefloatimage3.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/c8c0acaa0f4b8819b3a5ef0c.png"},{"id":98208664,"identity":"bab9c621-1f48-4267-a124-1558bc92aa3a","added_by":"auto","created_at":"2025-12-15 09:10:21","extension":"png","order_by":128,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":30450,"visible":true,"origin":"","legend":"","description":"","filename":"Onlinefloatimage4.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/ea7f4a034185b1a276196cdc.png"},{"id":98208802,"identity":"637f3aab-8c5d-4f96-8ce9-e8fcb9fe8f7f","added_by":"auto","created_at":"2025-12-15 09:10:29","extension":"png","order_by":129,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":45322,"visible":true,"origin":"","legend":"","description":"","filename":"Onlinefloatimage5.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/63a0dc3226e2532ae8b34adb.png"},{"id":98432674,"identity":"361a8b5d-044c-4257-9daa-446f8b497805","added_by":"auto","created_at":"2025-12-17 16:49:47","extension":"png","order_by":130,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":87530,"visible":true,"origin":"","legend":"","description":"","filename":"Onlinefloatimage6.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/409ab9faa5e457e1e3b2a8b5.png"},{"id":98431455,"identity":"11def35a-1248-4606-b448-2bdcca5a51e7","added_by":"auto","created_at":"2025-12-17 16:47:43","extension":"png","order_by":131,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":45970,"visible":true,"origin":"","legend":"","description":"","filename":"Onlinefloatimage7.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/7074ad7d4b29d7975d0d53d7.png"},{"id":98208698,"identity":"bc52ffca-ab3a-4a26-9cf9-33c4451109e3","added_by":"auto","created_at":"2025-12-15 09:10:23","extension":"png","order_by":132,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":21266,"visible":true,"origin":"","legend":"","description":"","filename":"Onlinefloatimage8.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/0b8f5b7180cbe61af3bdbfa5.png"},{"id":98431167,"identity":"23d348b8-edb4-43d6-9f38-c5347b082d39","added_by":"auto","created_at":"2025-12-17 16:47:11","extension":"png","order_by":133,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":16009,"visible":true,"origin":"","legend":"","description":"","filename":"Onlinefloatimage9.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/7a86ede112beda2b5c36f770.png"},{"id":98208744,"identity":"845273cb-3036-4865-93f9-3c94795c280c","added_by":"auto","created_at":"2025-12-15 09:10:26","extension":"png","order_by":134,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":337,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage10.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/f1d60f94e0a7f01206ba3bde.png"},{"id":98208713,"identity":"6743d3ca-1727-4f32-ae68-21e9d58500ef","added_by":"auto","created_at":"2025-12-15 09:10:24","extension":"png","order_by":135,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":287,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage101.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/a734d9520075d9519d348022.png"},{"id":98433036,"identity":"38e21df9-08d4-42b3-87af-1bac5f6a39bf","added_by":"auto","created_at":"2025-12-17 16:50:12","extension":"png","order_by":136,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":550,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage102.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/806e1dfe9d2a909ce54d87e7.png"},{"id":98431326,"identity":"04fe4eba-0f79-42b7-8bba-61428e5cfc79","added_by":"auto","created_at":"2025-12-17 16:47:32","extension":"png","order_by":137,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":290,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage103.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/ba1d8f14c6996c5f2da41972.png"},{"id":98432475,"identity":"f6bde67f-6851-42c6-b457-bc89c9f96dca","added_by":"auto","created_at":"2025-12-17 16:49:35","extension":"png","order_by":138,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":264,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage104.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/945ece53641a6ed3eb7e8422.png"},{"id":98208784,"identity":"489cb474-7741-480c-b371-6360a902515e","added_by":"auto","created_at":"2025-12-15 09:10:28","extension":"png","order_by":139,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":447,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage105.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/b684ad80ba3876ae243d7bb5.png"},{"id":98432052,"identity":"91b9fc51-d908-4a85-a862-316f69446199","added_by":"auto","created_at":"2025-12-17 16:48:53","extension":"png","order_by":140,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":447,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage105.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/8337d22514044488058b987a.png"},{"id":98208868,"identity":"9f681cf7-4ed0-4299-99de-b5c4482d5e37","added_by":"auto","created_at":"2025-12-15 09:10:33","extension":"png","order_by":141,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":812,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage107.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/cfd817c92671df56d96f9500.png"},{"id":98432371,"identity":"dc88b596-3c15-46f6-9de3-433e9a68d577","added_by":"auto","created_at":"2025-12-17 16:49:28","extension":"png","order_by":142,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":443,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage108.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/9767a6e6a58ee340648b70e7.png"},{"id":98208715,"identity":"f98ca71f-c272-4525-be97-0051fc5beaeb","added_by":"auto","created_at":"2025-12-15 09:10:24","extension":"png","order_by":143,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1210,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage109.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/eab9454dfa6201bd67e3db98.png"},{"id":98433274,"identity":"b59ae5b2-19e0-44f3-8938-1e6b83794c11","added_by":"auto","created_at":"2025-12-17 16:50:33","extension":"png","order_by":144,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":586,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage11.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/9fd9377ffbaf2ecab878e2dc.png"},{"id":98432888,"identity":"068d6209-8684-43c2-a83c-513a381fca3f","added_by":"auto","created_at":"2025-12-17 16:50:05","extension":"png","order_by":145,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":437,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage110.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/564ab26ce7982d02686b9d74.png"},{"id":98208861,"identity":"81819fd2-242a-4410-8734-83644fe7e03d","added_by":"auto","created_at":"2025-12-15 09:10:32","extension":"png","order_by":146,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":979,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage111.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/efc5d33acbc7e7c40e77a380.png"},{"id":98208853,"identity":"7ffb62cb-1da5-4364-8842-6502bde32ff2","added_by":"auto","created_at":"2025-12-15 09:10:31","extension":"png","order_by":147,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":3141,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage12.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/9828ec522791d1172bd6de50.png"},{"id":98208810,"identity":"f3258cd7-bf22-4517-b122-c7e6abf9d84e","added_by":"auto","created_at":"2025-12-15 09:10:29","extension":"png","order_by":148,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":398,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage13.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/0c18783c7f67c7be17097f0e.png"},{"id":98208696,"identity":"1d981747-1c12-440a-9b45-136f11229e3f","added_by":"auto","created_at":"2025-12-15 09:10:23","extension":"png","order_by":149,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":741,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage14.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/c116569b2782a4a76fe79585.png"},{"id":98432074,"identity":"c591934f-3200-44f7-b3f9-4c40b18a720e","added_by":"auto","created_at":"2025-12-17 16:48:55","extension":"png","order_by":150,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":768,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage15.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/e8bd147299e315d29033a193.png"},{"id":98432128,"identity":"548c019a-f7fe-4546-82fd-3da79cd49b21","added_by":"auto","created_at":"2025-12-17 16:49:03","extension":"png","order_by":151,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":488,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage19.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/840fa8e2c9f7e086f1ca86e2.png"},{"id":98431956,"identity":"bd13ea75-e86e-4ec2-899f-186ce9d615e6","added_by":"auto","created_at":"2025-12-17 16:48:42","extension":"png","order_by":152,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":451,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage20.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/f49a29d36c9cfe3457691219.png"},{"id":98431733,"identity":"d579dbae-6f5f-4308-a7a6-378158ed2d52","added_by":"auto","created_at":"2025-12-17 16:48:15","extension":"png","order_by":153,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":210,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage21.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/a3a988918425bc1168c9415c.png"},{"id":98208871,"identity":"253c105c-999e-4e9b-b1c6-020371a9f44e","added_by":"auto","created_at":"2025-12-15 09:10:33","extension":"png","order_by":154,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":219,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage22.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/3b9caa164be246bd57f84681.png"},{"id":98431488,"identity":"aa04fe87-3ca4-4955-bbf9-45a63f4ddd5f","added_by":"auto","created_at":"2025-12-17 16:47:47","extension":"png","order_by":155,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":618,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage23.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/b16c4afaaf952d49ebfdcbe6.png"},{"id":98433251,"identity":"eacefe81-3326-440c-9537-527365213a06","added_by":"auto","created_at":"2025-12-17 16:50:31","extension":"png","order_by":156,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":3673,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage24.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/79805a2a701fa8985444386b.png"},{"id":98431217,"identity":"8f0ffc24-1aa1-4971-86ff-cacc500c5b31","added_by":"auto","created_at":"2025-12-17 16:47:16","extension":"png","order_by":157,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1132,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage25.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/8907412301379d2a9ec5bebd.png"},{"id":98208827,"identity":"2fcb4e1c-3eaa-4a1a-aa51-b418f023853f","added_by":"auto","created_at":"2025-12-15 09:10:30","extension":"png","order_by":158,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1100,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage26.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/b0f248f2ddff13760b9d7f34.png"},{"id":98431796,"identity":"9bd0b488-16f7-448e-928a-fbacc4ad8a78","added_by":"auto","created_at":"2025-12-17 16:48:22","extension":"png","order_by":159,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":983,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage27.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/9b9b4be969f7e8d234192b10.png"},{"id":98208732,"identity":"6e36b3bb-ebfe-4979-a215-7d294bd9bafb","added_by":"auto","created_at":"2025-12-15 09:10:26","extension":"png","order_by":160,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":995,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage28.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/edd4b27bc105fc52aeebe5b8.png"},{"id":98433042,"identity":"856597a2-74ec-4f3a-b55f-9899e9ff0c1f","added_by":"auto","created_at":"2025-12-17 16:50:12","extension":"png","order_by":161,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1002,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage29.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/278455254a46a1542f005fbc.png"},{"id":98431716,"identity":"5ed1e463-c32b-4c40-98e4-3c2d6919e2a5","added_by":"auto","created_at":"2025-12-17 16:48:13","extension":"png","order_by":162,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":273,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage3.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/0b1ecec7eb2ee2c6d3f58704.png"},{"id":98431216,"identity":"eba4b03a-691a-449d-ac54-297cecacc4c9","added_by":"auto","created_at":"2025-12-17 16:47:16","extension":"png","order_by":163,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1009,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage30.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/8a5cd319987c545c9e2cdfa0.png"},{"id":98208662,"identity":"5a0c636e-5732-4574-b810-5131c3a52a02","added_by":"auto","created_at":"2025-12-15 09:10:21","extension":"png","order_by":164,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":443,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage31.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/d30d49dffd4dd187ecf21aab.png"},{"id":98208860,"identity":"ec0b001c-4660-4840-b91e-f7b2cb914d26","added_by":"auto","created_at":"2025-12-15 09:10:32","extension":"png","order_by":165,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":443,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage31.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/e7455bafd1033c24deeb79cd.png"},{"id":98431259,"identity":"acac3952-5805-4369-a3fe-3594fe471210","added_by":"auto","created_at":"2025-12-17 16:47:23","extension":"png","order_by":166,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":2579,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage33.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/5eaea9cf494a940754734570.png"},{"id":98432105,"identity":"8e4b7dd9-35a2-49eb-b462-f6de96646fa5","added_by":"auto","created_at":"2025-12-17 16:48:58","extension":"png","order_by":167,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":443,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage31.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/9d80cc9fc86c7f9a9239d818.png"},{"id":98432926,"identity":"d7497513-063f-447d-bb02-6cc06e695988","added_by":"auto","created_at":"2025-12-17 16:50:07","extension":"png","order_by":168,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":806,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage35.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/8aab2df6538bd415edcbfb30.png"},{"id":98208776,"identity":"76db9e09-2d84-45ef-8aac-f99c597d6221","added_by":"auto","created_at":"2025-12-15 09:10:27","extension":"png","order_by":169,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":526,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage36.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/3f3253b6885cb374bf841bce.png"},{"id":98433222,"identity":"896abd3a-d0e2-4e70-836c-86096043142c","added_by":"auto","created_at":"2025-12-17 16:50:28","extension":"png","order_by":170,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":11104,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage37.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/cb5e5b95f5bd0c07b0e6eeda.png"},{"id":98208838,"identity":"d14109c0-8b0e-4949-90df-4b8169eab77c","added_by":"auto","created_at":"2025-12-15 09:10:31","extension":"png","order_by":171,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":420,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage38.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/f2798a91c678e2aa1ae167f2.png"},{"id":98432724,"identity":"232aa958-427c-472c-b8f4-d79c91b5129f","added_by":"auto","created_at":"2025-12-17 16:49:51","extension":"png","order_by":172,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":281,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage39.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/4116cf7efac1fb61abb1e518.png"},{"id":98432856,"identity":"30ee1d8b-14de-48cb-807e-f64da166a0c3","added_by":"auto","created_at":"2025-12-17 16:50:03","extension":"png","order_by":173,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":292,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage4.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/beaa6835c60efc413abcab10.png"},{"id":98208816,"identity":"bfcd40cd-8613-4dfe-8fe5-8b65318175af","added_by":"auto","created_at":"2025-12-15 09:10:29","extension":"png","order_by":174,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1204,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage40.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/a940a744ac0ab98a4dcb2217.png"},{"id":98208688,"identity":"a2f05f19-a102-4847-99e4-ce730b49cfc3","added_by":"auto","created_at":"2025-12-15 09:10:23","extension":"png","order_by":175,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":271,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage42.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/5c7db9585bce0072b698242c.png"},{"id":98431192,"identity":"c5241d29-cbcb-489e-b5dd-35880769638f","added_by":"auto","created_at":"2025-12-17 16:47:14","extension":"png","order_by":176,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1060,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage43.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/8e45e94d541d53ab35e30aa3.png"},{"id":98208706,"identity":"7e6ade6d-faca-43cd-949b-0776bd6ed4c8","added_by":"auto","created_at":"2025-12-15 09:10:24","extension":"png","order_by":177,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":426,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage44.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/a2e960809644b3f9f0045ee5.png"},{"id":98431294,"identity":"9bca5240-5c3e-4b77-a218-1e6eba2f3a15","added_by":"auto","created_at":"2025-12-17 16:47:29","extension":"png","order_by":178,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1757,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage45.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/bbd97df68d083a0050b0bdd8.png"},{"id":98433002,"identity":"8468955c-f256-4531-9c11-d72b57139f84","added_by":"auto","created_at":"2025-12-17 16:50:11","extension":"png","order_by":179,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":822,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage46.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/9db0e0afb21edfc786f2f60c.png"},{"id":98432588,"identity":"cdcaa4af-2376-4e1e-a213-8c4762b7a670","added_by":"auto","created_at":"2025-12-17 16:49:43","extension":"png","order_by":180,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":296,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage47.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/e49ff416bff71687685bc992.png"},{"id":98432957,"identity":"f3bafdfa-42c9-48e4-9aff-d8837c4a5a30","added_by":"auto","created_at":"2025-12-17 16:50:08","extension":"png","order_by":181,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":351,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage48.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/fd29214a5c524d674cd1d062.png"},{"id":98432087,"identity":"6be23f56-a5fa-4ffe-b028-e261b902616a","added_by":"auto","created_at":"2025-12-17 16:48:57","extension":"png","order_by":182,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":340,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage49.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/6c9b5ae17a11b48748120c3f.png"},{"id":98208690,"identity":"418e588a-02ff-497e-a7ed-4b2b5f5d0fcc","added_by":"auto","created_at":"2025-12-15 09:10:23","extension":"png","order_by":183,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":466,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage5.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/e24e1af8f8fa4930132eaeff.png"},{"id":98208720,"identity":"2e9f964e-1016-4dab-959e-7a4063267af7","added_by":"auto","created_at":"2025-12-15 09:10:24","extension":"png","order_by":184,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":532,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage50.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/fa8134804d38c3ee6aa63064.png"},{"id":98432602,"identity":"bd27dbfc-92e0-4c1e-9008-985a92826d34","added_by":"auto","created_at":"2025-12-17 16:49:44","extension":"png","order_by":185,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":426,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage44.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/7467f1ecdb02edd4777b1e98.png"},{"id":98208798,"identity":"60ac1b7e-c241-4965-bdbd-f715cbe0284c","added_by":"auto","created_at":"2025-12-15 09:10:28","extension":"png","order_by":186,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":508,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage52.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/cef01e885eeec23647540f0b.png"},{"id":98208849,"identity":"a8027411-dcc8-49d9-8c19-4c67db7f8083","added_by":"auto","created_at":"2025-12-15 09:10:31","extension":"png","order_by":187,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":647,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage53.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/d1c4766423a232a3d0af2b74.png"},{"id":98208657,"identity":"b29391dc-604a-4bb7-b9d6-8210b2208de2","added_by":"auto","created_at":"2025-12-15 09:10:20","extension":"png","order_by":188,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1519,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage54.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/944069c477d0ffe88ce62395.png"},{"id":98431649,"identity":"bff0325f-eee7-4ed3-8b7b-0bb67f6cf900","added_by":"auto","created_at":"2025-12-17 16:48:05","extension":"png","order_by":189,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1311,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage55.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/4bac3123ebfc24dc1e624b6c.png"},{"id":98431355,"identity":"153d0a78-ac46-4b36-a39f-11f92fa52811","added_by":"auto","created_at":"2025-12-17 16:47:33","extension":"png","order_by":190,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":438,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage56.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/a7f393cedaca3f0976be344f.png"},{"id":98208772,"identity":"f6f9d14f-8c8e-4a93-b341-deb4053a2ad8","added_by":"auto","created_at":"2025-12-15 09:10:27","extension":"png","order_by":191,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":925,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage57.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/e1c830e8a8178cf385801e41.png"},{"id":98432953,"identity":"6d2d7605-b31d-4adf-9855-012f832669b3","added_by":"auto","created_at":"2025-12-17 16:50:08","extension":"png","order_by":192,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":857,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage58.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/eb4d3d974f89fc8c52fe686b.png"},{"id":98208778,"identity":"dc040494-cc4b-42a2-b2d4-78365092bbe6","added_by":"auto","created_at":"2025-12-15 09:10:27","extension":"png","order_by":193,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":518,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage6.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/7e36aab101c205972605b201.png"},{"id":98208847,"identity":"f4670d33-cb12-4afd-a6ee-bbd1831e8f56","added_by":"auto","created_at":"2025-12-15 09:10:31","extension":"png","order_by":194,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":949,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage61.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/4db5d137d5564360b0844015.png"},{"id":98623055,"identity":"6e167643-b2d7-45fa-8dcf-7ca8b1ef996b","added_by":"auto","created_at":"2025-12-19 17:04:20","extension":"png","order_by":195,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":219,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage22.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/fd1fe83a55c8c8940d3308d1.png"},{"id":98431338,"identity":"59336caf-ce6f-47b9-8a72-87d516274698","added_by":"auto","created_at":"2025-12-17 16:47:33","extension":"png","order_by":196,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":323,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage63.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/3a14b8cf2ea0d092bab1ab1d.png"},{"id":98432736,"identity":"022ac6f1-5ca7-42e6-bd4d-5b24d0acc087","added_by":"auto","created_at":"2025-12-17 16:49:54","extension":"png","order_by":197,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":352,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage64.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/a3bb7d7e04518b0b41d66636.png"},{"id":98208699,"identity":"5a187749-33e1-4579-bceb-51645cfb3faf","added_by":"auto","created_at":"2025-12-15 09:10:23","extension":"png","order_by":198,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":318,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage65.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/05a515738a7e38dd843ae9d7.png"},{"id":98431274,"identity":"c5739fe0-2c1f-4976-acf5-dfa77f773859","added_by":"auto","created_at":"2025-12-17 16:47:25","extension":"png","order_by":199,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":446,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage66.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/868452b328a09c3d6ed92ac4.png"},{"id":98432086,"identity":"d14a3dbf-5256-4004-8b04-765071dc5a97","added_by":"auto","created_at":"2025-12-17 16:48:57","extension":"png","order_by":200,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":742,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage67.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/46a6eb3d103fac6e3f028442.png"},{"id":98433220,"identity":"d7776490-90a9-447d-9eb5-dc177f9ba9da","added_by":"auto","created_at":"2025-12-17 16:50:28","extension":"png","order_by":201,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":297,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage68.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/420bb73057f7cc3b20fbde91.png"},{"id":98208875,"identity":"355d3634-c347-43bd-8ad9-b00dcc934859","added_by":"auto","created_at":"2025-12-15 09:10:33","extension":"png","order_by":202,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":323,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage63.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/0248f4e15a1aba4c3b5a78ef.png"},{"id":98433178,"identity":"0f4dbdd1-1f8b-46aa-940c-9d70a51ad971","added_by":"auto","created_at":"2025-12-17 16:50:22","extension":"png","order_by":203,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":330,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage70.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/c9bc183ff7a90e1ddce62bfe.png"},{"id":98208841,"identity":"a13e5939-44f4-42df-9c3f-aed56dabf186","added_by":"auto","created_at":"2025-12-15 09:10:31","extension":"png","order_by":204,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":460,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage71.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/1541263e152bfc4859f55ec8.png"},{"id":98432917,"identity":"55b0e80f-d7be-443b-b862-cc3941fa17f6","added_by":"auto","created_at":"2025-12-17 16:50:07","extension":"png","order_by":205,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":868,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage72.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/38ad3e8f67e2f6410fd65bfd.png"},{"id":98208749,"identity":"84081556-8253-4582-b6e5-dafaefff6936","added_by":"auto","created_at":"2025-12-15 09:10:26","extension":"png","order_by":206,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":905,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage73.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/66ff0e891849d8a2e4630812.png"},{"id":98208879,"identity":"56bc10f9-8983-4ccb-a570-b39015a8386a","added_by":"auto","created_at":"2025-12-15 09:10:34","extension":"png","order_by":207,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":918,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage74.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/62e0606c18d33f6c57f76d3b.png"},{"id":98432977,"identity":"dca45783-ee60-4dab-b00c-cec199cb4ca1","added_by":"auto","created_at":"2025-12-17 16:50:10","extension":"png","order_by":208,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1645,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage75.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/a360c4a9abbdb6f1e4c5ab6e.png"},{"id":98208702,"identity":"8845f0bb-4343-4926-8e12-aebdfbb106c7","added_by":"auto","created_at":"2025-12-15 09:10:24","extension":"png","order_by":209,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1740,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage76.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/e82b5d1296c95a19e6e001ac.png"},{"id":98208660,"identity":"50728005-28b4-4367-bded-c6cd11619ba6","added_by":"auto","created_at":"2025-12-15 09:10:20","extension":"png","order_by":210,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":261,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage77.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/310ebbe87dce30c50193816c.png"},{"id":98430790,"identity":"f8cfaeac-92a3-4a71-ae7a-3c21151194d2","added_by":"auto","created_at":"2025-12-17 16:46:13","extension":"png","order_by":211,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":219,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage78.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/5b6d9bdf6d3460d0f56a101b.png"},{"id":98431351,"identity":"69b8e65a-7760-4b75-b0b1-47b61abac23f","added_by":"auto","created_at":"2025-12-17 16:47:33","extension":"png","order_by":212,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":625,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage79.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/d8b830f639daa83b5104b4a9.png"},{"id":98208830,"identity":"a83ed4ed-f266-4f05-90e2-2cc65a1bd850","added_by":"auto","created_at":"2025-12-15 09:10:30","extension":"png","order_by":213,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":2535,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage8.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/64ef0fb12c1e2917dd5c7fb4.png"},{"id":98433293,"identity":"8ae9f45f-c22d-475b-942e-abc200f13bec","added_by":"auto","created_at":"2025-12-17 16:50:34","extension":"png","order_by":214,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":284,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage80.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/f65b71ee5e784c605c1b403a.png"},{"id":98208729,"identity":"2756400c-a0a5-4c95-a330-05ce55a49757","added_by":"auto","created_at":"2025-12-15 09:10:25","extension":"png","order_by":215,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":577,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage81.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/5d8c27064c8753cec22ca5ae.png"},{"id":98208765,"identity":"9bf652a0-d4e0-4148-b6dd-331432ec8523","added_by":"auto","created_at":"2025-12-15 09:10:27","extension":"png","order_by":216,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":317,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage82.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/700c5e5f81464b401f400258.png"},{"id":98208743,"identity":"0cf6c2c0-6dba-474f-835b-030087dadf92","added_by":"auto","created_at":"2025-12-15 09:10:26","extension":"png","order_by":217,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":299,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage83.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/117a12af3654373dbaa7c268.png"},{"id":98431299,"identity":"b31f0cf5-34ea-4aa7-9148-0289c4884406","added_by":"auto","created_at":"2025-12-17 16:47:29","extension":"png","order_by":218,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":498,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage84.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/b1744d7a7b2c8b8784a620e7.png"},{"id":98208759,"identity":"98d4f49d-614f-4c4c-85b4-e8a320f983d2","added_by":"auto","created_at":"2025-12-15 09:10:27","extension":"png","order_by":219,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":2296,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage85.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/47b610971acfaea4ff6645a1.png"},{"id":98208870,"identity":"52029cc0-9d67-4058-9418-6439a9433d05","added_by":"auto","created_at":"2025-12-15 09:10:33","extension":"png","order_by":220,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1170,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage86.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/cfe45d867ba4200017515d32.png"},{"id":98432869,"identity":"5305a104-3329-4631-93da-d76b0ff52da9","added_by":"auto","created_at":"2025-12-17 16:50:04","extension":"png","order_by":221,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":881,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage87.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/f030b2a304e2eb15efd272c5.png"},{"id":98432129,"identity":"7f1271b2-95d5-4fc5-9080-83c8f0905c4f","added_by":"auto","created_at":"2025-12-17 16:49:03","extension":"png","order_by":222,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":241,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage88.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/2f6d66ad467597b6f22de14b.png"},{"id":98208880,"identity":"b37e951c-4288-4888-97aa-d477c1b716d5","added_by":"auto","created_at":"2025-12-15 09:10:34","extension":"png","order_by":223,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":284,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage80.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/ef79f7cbd5b0a78a631ab4eb.png"},{"id":98432756,"identity":"b6835a60-d8da-4732-8d5c-3d3a9f69a384","added_by":"auto","created_at":"2025-12-17 16:49:54","extension":"png","order_by":224,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":608,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage9.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/d78259692f645ba158e7b384.png"},{"id":98432039,"identity":"6cf1e459-c481-4652-bb0a-746157dad9a2","added_by":"auto","created_at":"2025-12-17 16:48:53","extension":"png","order_by":225,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":313,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage90.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/34587fa73bb8ddd6776f9f0a.png"},{"id":98208737,"identity":"fc14b88a-2781-4214-ab84-f9f7cb2e01f8","added_by":"auto","created_at":"2025-12-15 09:10:26","extension":"png","order_by":226,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":299,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage83.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/7c127c8530c3f1e747e7b4f0.png"},{"id":98208716,"identity":"aaec2c52-84dc-4b56-ab59-fc31be20a1fe","added_by":"auto","created_at":"2025-12-15 09:10:24","extension":"png","order_by":227,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1390,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage92.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/363475557b34db0c8cd38e65.png"},{"id":98432382,"identity":"08e30245-21d7-4000-b15d-71feba776e3c","added_by":"auto","created_at":"2025-12-17 16:49:29","extension":"png","order_by":228,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":568,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage93.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/4390ed651020738dc8a0444b.png"},{"id":98208762,"identity":"e3ce2068-adae-42b6-aebc-1dc787db051b","added_by":"auto","created_at":"2025-12-15 09:10:27","extension":"png","order_by":229,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":1434,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage94.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/2c28ca3f9f3220a0d40841ca.png"},{"id":98208807,"identity":"8ae3e362-ff33-455f-aead-b2178b9024fa","added_by":"auto","created_at":"2025-12-15 09:10:29","extension":"png","order_by":230,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":485,"visible":true,"origin":"","legend":"","description":"","filename":"Onlineimage97.png","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/ab25015cd025c08e5dabb2df.png"},{"id":98208876,"identity":"dcf41e1c-a442-4142-9191-442f234a0957","added_by":"auto","created_at":"2025-12-15 09:10:34","extension":"xml","order_by":231,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":148884,"visible":true,"origin":"","legend":"","description":"","filename":"JAMTD25069340structuring.xml","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/561fa41b5e3a024e0d878a85.xml"},{"id":98431291,"identity":"1126006b-b094-4251-a2b2-0af637603919","added_by":"auto","created_at":"2025-12-17 16:47:28","extension":"html","order_by":232,"title":"","display":"","copyAsset":false,"role":"acdc-reference","size":162240,"visible":true,"origin":"","legend":"","description":"","filename":"earlyproof.html","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1/a750b0b477b3413462ed5c98.html"},{"id":98631287,"identity":"3dfbc177-908b-432c-a36b-729219f37fc1","added_by":"auto","created_at":"2025-12-19 17:19:45","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":1203765,"visible":true,"origin":"","legend":"","description":"","filename":"manuscript11.30.2.pdf","url":"https://assets-eu.researchsquare.com/files/rs-8241347/v1_covered_5df2cc54-8801-411e-801d-bfc424ce8a7b.pdf"}],"financialInterests":"","formattedTitle":"Axis-Space Synchronized Motion Error Estimation for Five-Axis Contour Error Control","fulltext":[],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":false,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":true,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"the-international-journal-of-advanced-manufacturing-technology","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"jamt","sideBox":"Learn more about [The International Journal of Advanced Manufacturing Technology](https://www.springer.com/journal/170)","snPcode":"170","submissionUrl":"https://submission.nature.com/new-submission/170/3","title":"The International Journal of Advanced Manufacturing Technology","twitterHandle":"","acdcEnabled":true,"dfaEnabled":true,"editorialSystem":"em","reportingPortfolio":"Springer Hybrid","inReviewEnabled":true,"inReviewRevisionsEnabled":false},"keywords":"—Five-axis machine tools, Sample generation, Tracking error prediction, LSTM, transformer","lastPublishedDoi":"10.21203/rs.3.rs-8241347/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-8241347/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003eThis study addresses the modeling and prediction of tracking error in CNC machine tool feed systems by developing a neural network prediction model based on an LSTM-Transformer architecture. To overcome the limitation of conventional data in adequately exciting the dynamic characteristics of servo systems, a featured trajectory construction method is proposed. By incorporating excitation trajectories that encompass various operating conditions\u0026mdash;such as startup stopping sequences, direction reversals, and speed variations\u0026mdash;the distribution of motion states in the training dataset is systematically enriched, thereby enhancing the model's ability to characterize nonlinear dynamic behaviors. Comparative experiments conducted under the same dataset with conventional LSTM and GRU networks demonstrate that the proposed modeling and featured trajectory design approach significantly reduces the prediction error of the feed system output while maintaining strong generalization performance under complex trajectories. This provides high-precision prior information for subsequent contour error analysis and compensation in CNC machine tools.\u003c/p\u003e","manuscriptTitle":"Axis-Space Synchronized Motion Error Estimation for Five-Axis Contour Error Control","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2025-12-15 09:09:31","doi":"10.21203/rs.3.rs-8241347/v1","editorialEvents":[{"type":"communityComments","content":0},{"type":"reviewerAgreed","content":"","date":"2025-12-13T13:00:56+00:00","index":0,"fulltext":""},{"type":"reviewersInvited","content":"","date":"2025-12-10T09:58:52+00:00","index":"","fulltext":""},{"type":"editorAssigned","content":"","date":"2025-12-02T05:47:31+00:00","index":"","fulltext":""},{"type":"submitted","content":"The International Journal of Advanced Manufacturing Technology","date":"2025-11-30T05:25:37+00:00","index":"","fulltext":""}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"the-international-journal-of-advanced-manufacturing-technology","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"jamt","sideBox":"Learn more about [The International Journal of Advanced Manufacturing Technology](https://www.springer.com/journal/170)","snPcode":"170","submissionUrl":"https://submission.nature.com/new-submission/170/3","title":"The International Journal of Advanced Manufacturing Technology","twitterHandle":"","acdcEnabled":true,"dfaEnabled":true,"editorialSystem":"em","reportingPortfolio":"Springer Hybrid","inReviewEnabled":true,"inReviewRevisionsEnabled":false}}],"origin":"","ownerIdentity":"a6eae179-fe43-48fb-befd-e48d68176172","owner":[],"postedDate":"December 15th, 2025","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"under-review","subjectAreas":[],"tags":[],"updatedAt":"2025-12-15T09:09:31+00:00","versionOfRecord":[],"versionCreatedAt":"2025-12-15 09:09:31","video":"","vorDoi":"","vorDoiUrl":"","workflowStages":[]},"version":"v1","identity":"rs-8241347","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-8241347","identity":"rs-8241347","version":["v1"]},"buildId":"XKTyCvWXoU3ODBz1xrDgd","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}