Long-Term Implications of Oophorectomy at the Time of Hysterectomy for Benign Disease

Donna Shoupe, Jonathan S. Berek
In: Amenorrhea · 2010 · pp. 187–201 · doi:10.1007/978-1-60327-864-5_11 · W195004484
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⚙ AI-generated summary by claude@2026-06, 2026-06-09 ⓘ

This paper reviews the long-term implications of concurrent hysterectomy and oophorectomy for benign disease, noting the high percentage of women undergoing both procedures.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-09 ⓘ

This paper/chapter discusses long-term implications of hysterectomy performed for benign disease, comparing outcomes when ovaries are removed (with oophorectomy) versus retained, drawing on national statistics on hysterectomy frequency and related long-term effects reported across the literature. It highlights that a large proportion of hysterectomies also involve oophorectomy, and it frames the need to consider downstream outcomes potentially influenced by earlier loss of ovarian hormones, including a range of physiologic domains discussed in cited studies. A major caveat is that the chapter is largely narrative and based on secondary data and references rather than presenting new original patient-level analyses. This paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Abstract

The National Center for Health Statistics report that in 2004, of the 617,000 ­hysterectomies performed in the USA, 73% also involved the surgical removal of the ovaries. In the United States, by age 60, about 1/3 of women undergo a hysterectomy [1, 2]. Over the past decade, an average of 622,000 hysterectomies per year have been performed, and it is now estimated that there are 22 million women in the USA who have undergone this procedure [2]. According to the CDC, 52% of all hysterectomies are performed in women aged 44 years of age or younger. Of over 3 million hysterectomies performed between 1994 and 1999 in the USA, slightly over 10% were done for a primary diagnosis of cancer (Table 11.1). It is important to recognize the long-term implications of hysterectomy with and without oophorectomy and to counsel patients accordingly.

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