Is There Any Relation Between Insulin Resistance and Menstrual Irregularity in Obese Women?

Objectives: Menstrual irregularity is a common issue in obese women that can cause anovulation and infertility. Insulin resistance is also common in obese women. We aimed to find the relation between menstrual pattern and insulin resistance in obese women. Results: : The samples were 233 obese women 18-36 years old coming to obesity clinic for treatment of obesity. We checked Homeostatic Model Assessment for Insulin Resistance (HOMA – IR) and lipid profile in the clients and also we filled a form including the age, educational status, marital status, menstrual pattern and severity of hirsutism. Sample size was 233. The mean age of women was 25.6±8 years. The mean Body mass index (BMI) was 44.6±4.8 kg/m2. 84.55% of women had insulin resistance. There was significant relation between menstrual pattern and fasting insulin level (p=0.05). There was no significant relation between presence of Insulin resistance and menstrual pattern (p=0.28). There was significant relation between age and menstrual pattern (p=0.007). Based on the results, there was no significant relation between HOMA- IR and menstrual pattern (p=0.28). Perhaps type of obesity (android) may have relation with menstrual pattern and also we need to a standard IR definition to explain the relation between different findings.