Efficiency of different biopsy methods of adenomyosis diagnosis, comparative analisis

In: Journal of obstetrics and women's diseases · 2005 · vol. 54(5S) , pp. 45 · doi:10.17816/jowd87373 · W3214337424
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Abstract

Introduction.Usage of low invasive methods in adenomyosis diagnosis helps to diagnose adenomyosis definitely by histological examination of myometrium samples.
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Abstract

Introduction.Usage of low invasive methods in adenomyosis diagnosis helps to diagnose adenomyosis definitely by histological examination of myometrium samples. Full Text Introduction.Usage of low invasive methods in adenomyosis diagnosis helps to diagnose adenomyosis definitely by histological examination of myometrium samples.

Material

and methods. Hysterectomy specimen (n=32), in 24 (75%) cases the adenomyosis was confirmed by pathologic examination. Imitation of transcervical and transabdominal puncture biopsy, pinch and resection biopsy in vitro were performed.

Results

- pinch biopsy is characterized by low volume of myometrium sample ~lmm3, unavailability to obtain deep located areas of myometrium, - resectobiopsy is characterized by unavailability to obtain deep located areas of myometrium, high side thermal necrosis, making 70% of preparation impossible for histological analysis. - Sensitivity of transcervical puncture biopsy for 5-nodular is 48%, 6-8 nodular - 83%, this method provides possibility to obtain deep located areas of myometrium; - transabdominal puncture biopsy gets tissue samples from external zones of myometrium, making impossible determine the depth of endometrial invasion. Sensitivity of transabdominal biopsy is 58% for 8-nodular biopsy. - 6-nodular transcervical biopsy - is the optimal method to obtain histological samples confirming adenomyosis. About the authors S. A. Povzun The D.O.Ott Research Institution of Obstetrics and Gynecology RAMS' Author for correspondence. Email: [email protected] Department of Pathological Anatomy Russian Federation, Saint PetersburgV. F. Bezhenar The D.O.Ott Research Institution of Obstetrics and Gynecology RAMS' Email: [email protected] Department of Pathological Anatomy Russian Federation, Saint PetersburgY. V. Tsvelev Medical-Military Academy Email: [email protected] Department of Obstetrics and Gynecology Russian Federation, Saint PetersburgD. B. Fridman The D.O.Ott Research Institution of Obstetrics and Gynecology RAMS'; Medical-Military Academy Email: [email protected] Department of Pathological Anatomy, Department of Obstetrics and Gynecology Russian Federation, Saint Petersburg; Saint Petersburg

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adenomyosis

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