Near-Infrared AIE Dots with Chemiluminescence for Deep-Tissue Imaging
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AI-generated summary
Researchers developed near-infrared AIE dots based on luminol that exhibit deep-tissue chemiluminescence capable of penetrating 3 cm of pork ham and differentiating tumor from normal tissue.
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Abstract
A novel AIEgen named TBL was designed based on the classic CL emitter luminol. The NIR CL emission of TBL dots could penetrate through 3 cm-thick pork ham, which is much better than NIR fluorescence and blue CL emission. Moreover, the successful differentiation of tumor and normal tissue makes this system promising for CL-guided tumor diagnosis and surgery.
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- europepmc
- last seen: 2026-05-19T01:45:01.086888+00:00