Incidence of Persistent Neonatal Hypoglycemia and Associated Factors among Neonatal Intensive Care Unit Admissions in South Gondar Public Hospitals, Northcentral Ethiopia: a prospective cross sectional study

Incidence of Persistent Neonatal Hypoglycemia and Associated Factors among Neonatal Intensive Care Unit Admissions in South Gondar Public Hospitals, Northcentral Ethiopia: a prospective cross sectional study | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Article Incidence of Persistent Neonatal Hypoglycemia and Associated Factors among Neonatal Intensive Care Unit Admissions in South Gondar Public Hospitals, Northcentral Ethiopia: a prospective cross sectional study Solomon kebede, Tigabu Munye, Kindu Agmas, Worku Necho, Natnael Moges This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-3823404/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Objective The aim of this study was to determine the incidence of persistent neonatal hypoglycemia and associated factors in south Gondar public hospitals, northcentral Ethiopia. Design and setting Prospective cross-sectional study for 400 neonates admitted in NICUs at public hospitals. Main results The incidence of persistent neonatal hypoglycemia (PHG) was found to be 94 ((23.5%); 95%CI (19.3%-28%)). Neonates with hypothermia (AOR=4.41; 95% CI=2.72-10.92), preterm birth (AOR=3.5; 95%CI=1.69-11.97), those with perinatal asphyxia (AOR=2.5; 95% CI=1.34-9.67), and neonates with pathological jaundice (AOR=2.3; 95% CI=1.21-10.34) were factors associated with persistent hypoglycemia. On the contrary, spontaneous vaginal delivery (SVD) was a protective factor (AOR=0.72; 95% CI=0.35-0.88). Conclusions The incidence of persistent neonatal hypoglycemia (PHG) was lower compared to previous studies while factors increasing the risk of PHG were Hypothermia, Pretermbirth, perinatal asphyxia (PNA), early onset of sepsis (EONS), and pathological jaundice. And, Spontaneous vaginal delivery (SVD) was a protective factor. Health sciences/Risk factors Health sciences/Medical research/Epidemiology Persistent hypoglycemia Neonatal hypoglycemia South Gondar Full Text Additional Declarations There is NO conflict of interest to disclose. Supplementary Files Suplementaryfile1.GlucometerforRBSmeasurement.pdf Suplementary file 1. Glucometer for RBS testing suplementaryfile2.docx Suplementary figure 2. Maternal health problems during pregnancy for incidence and associated factors of persistent hypoglycemia among admitted neonates in NICU, at South Gondar Public Hospi Suplementaryfile3.docx Suplementary figure 3. Types of maternal pregnancy health problems for incidence and associated factors of persistent hypoglycemia among admitted neonates in NICU, South Gondar Public hospitals, 2022. Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-3823404","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Article","associatedPublications":[],"authors":[{"id":264895462,"identity":"1c8b71ec-2e6e-4d14-973d-4ade56c4b383","order_by":0,"name":"Solomon kebede","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAA4klEQVRIiWNgGAWjYFAC5gYQydgAQh+ALDZ2gloYEVoYZ4C0MBOvBWghD9haAhrk2xsbH92ouCPbL3a4+bPNr23yfMwMjB8+5uDWYnDmYLNxzplnxjNnJ7ZJ5/bdNmxjZmCWnLkNjxYJkMq2w4kbbie2Mef23GYEamFj5sWjRX4GVMv+24nNny17btsT1MJwA2aLdGKDNMMPkF0EtED9cth4BlCxZG/D7eQ2ZsZmvH6Rb28++Din4rBs/+z0xx9+/LltOx8o8uEjPoehAMY2MNlArHoQ+EOK4lEwCkbBKBgpAACKFVdc+pstTAAAAABJRU5ErkJggg==","orcid":"","institution":"Debre Tabor University","correspondingAuthor":true,"prefix":"","firstName":"Solomon","middleName":"","lastName":"kebede","suffix":""},{"id":264895463,"identity":"c50045f7-6113-4a3b-b712-1321342fae7d","order_by":1,"name":"Tigabu Munye","email":"","orcid":"","institution":"Debre Tabor University","correspondingAuthor":false,"prefix":"","firstName":"Tigabu","middleName":"","lastName":"Munye","suffix":""},{"id":264895464,"identity":"5cb61aff-c638-4061-a00a-fca1d44194f7","order_by":2,"name":"Kindu Agmas","email":"","orcid":"","institution":"Debre Tabor Comprehensive Specialized Hospital","correspondingAuthor":false,"prefix":"","firstName":"Kindu","middleName":"","lastName":"Agmas","suffix":""},{"id":264895465,"identity":"de2df932-3442-4d0d-9aa1-7de4982d7fdf","order_by":3,"name":"Worku Necho","email":"","orcid":"","institution":"Debre Tabor University","correspondingAuthor":false,"prefix":"","firstName":"Worku","middleName":"","lastName":"Necho","suffix":""},{"id":264895466,"identity":"b72766df-24a4-40d1-a100-dc42dc3c2ac7","order_by":4,"name":"Natnael Moges","email":"","orcid":"","institution":"Debre Tabor University","correspondingAuthor":false,"prefix":"","firstName":"Natnael","middleName":"","lastName":"Moges","suffix":""}],"badges":[],"createdAt":"2023-12-30 07:25:13","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-3823404/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-3823404/v1","draftVersion":[],"editorialEvents":[],"editorialNote":"","failedWorkflow":false,"files":[{"id":51652422,"identity":"7b55f52b-9a40-4770-8cb1-1e9fe502b408","added_by":"auto","created_at":"2024-02-26 15:48:54","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":530895,"visible":true,"origin":"","legend":"","description":"","filename":"ManuscriptPHGJOPed.pdf","url":"https://assets-eu.researchsquare.com/files/rs-3823404/v1_covered_f37377c8-6560-48c0-885c-26f37f381afe.pdf"},{"id":49179137,"identity":"ec4cf75c-749e-4b6e-abf7-edfca7b0c6aa","added_by":"auto","created_at":"2024-01-04 13:45:21","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"supplement","size":90499,"visible":true,"origin":"","legend":"Suplementary file 1. 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Types of maternal pregnancy health problems for incidence and associated factors of persistent hypoglycemia among admitted neonates in NICU, South Gondar Public hospitals, 2022.","description":"","filename":"Suplementaryfile3.docx","url":"https://assets-eu.researchsquare.com/files/rs-3823404/v1/78f305e7cc1304960bd85aaa.docx"}],"financialInterests":"There is \u003cb\u003eNO\u003c/b\u003e conflict of interest to disclose.","formattedTitle":"Incidence of Persistent Neonatal Hypoglycemia and Associated Factors among Neonatal Intensive Care Unit Admissions in South Gondar Public Hospitals, Northcentral Ethiopia: a prospective cross sectional study","fulltext":[],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":true,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":true,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"Persistent hypoglycemia, Neonatal hypoglycemia, South Gondar","lastPublishedDoi":"10.21203/rs.3.rs-3823404/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-3823404/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003e\u003cstrong\u003eObjective \u003c/strong\u003eThe aim of this study was to determine the incidence of persistent neonatal hypoglycemia and associated factors in south Gondar public hospitals, northcentral Ethiopia.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eDesign and setting\u003c/strong\u003e Prospective cross-sectional study for 400 neonates admitted in NICUs at public hospitals.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eMain results\u003c/strong\u003e The incidence of persistent neonatal hypoglycemia (PHG) was found to be 94 ((23.5%); 95%CI (19.3%-28%)). 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