Abnormal pathology seen on appendectomy in patients with predominant right-sided pelvic pain

Catherine W. Cai, Katelin Sisler, Jeffrey A. Gavard, Jose D Eugenio-Colon, P.P. Yeung
In: Journal of Endometriosis and Pelvic Pain Disorders · 2020 · vol. 12(3-4) , pp. 142–150 · doi:10.1177/2284026520924904 · W3037307598
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⚙ AI-generated summary by claude@2026-06, 2026-06-21 ⓘ

This study found no significant difference in abnormal appendix pathology between women with right-sided or non-right-sided chronic pelvic pain, despite a high overall rate of appendix pathology.

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Abstract

Introduction: Previous studies have linked chronic pelvic pain (CPP) to appendix pathologies. However, few studies have investigated appendix pathology specifically in the context of CPP that is right-side predominant (R-CPP). We hypothesized that women with R-CPP have higher rates of appendix pathology compared with women with CPP that is not right-side predominant (N-CPP). Methods: We conducted a retrospective case–control study of 220 women who underwent diagnostic laparoscopy and planned or incidental appendectomy for CPP and suspected endometriosis between January 2015 and December 2018 at a tertiary care center in Saint Louis, MO. Results: No significant difference in abnormal appendix pathology was found between women with R-CPP and women with N-CPP (30.9% vs 34.5%, p = 0.74, odds ratio = 0.85, 95% CI: (0.44, 1.62)). Gross abnormalities of the appendix were documented in 40 of 220 patients (18.2%), with the most common abnormal gross findings being adhesions (8.2%), followed by abnormal lesions (7.3%). Conclusion: In this study, the presence of abnormal pathology within the appendix did not correlate with R-CPP, indicating triage based on predominant pain location cannot help identify patients with underlying appendix pathology. However, consistent with previous studies, we identified a high rate of abnormal appendix pathology overall, supporting the practice of many surgeons to perform routine appendectomy in women with CPP.

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endometriosischronic_pelvic_pain

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