Clinical Outcome of Endovascular Coil Embolization For Cerebral Aneurysms In Asian Population In Relation To Risk Factors: A 3-Year Retrospective Analysis

Background: 
This study reviews the impact of comorbidities on the success of endovascular coiling of both ruptured and unruptured intracranial aneurysms. Independent risk factors reviewed were age, sex, smoking and hypertension. Methods A 3-year retrospective analysis, performed to assess the clinical outcomes of patients with cerebral aneurysms treated endovascularly in Asian population. A total of 297 patients treated at a single center were included. Clinical outcomes were evaluated by regular follow-ups. A modified Rankin Scale was used to measure the clinical outcomes in patients. Results Study showed smoking had an adverse effect on clinical outcome, with smokers 35% less likely to recover, while hypertension played a minimal role with only 15%. It was found that aneurysms are more prevalent in women but women have a better chance of recovery. Men in their 20s and 30s have the best recovery, with comorbidities playing a negligible role. Similarly, patients who were above 40 had a lower chance of recovery compared to younger patients due to comorbidities irrespective of gender.
 Conclusions: Asian sub-continent has different genetic marker that lead to poorer outcomes of aneurysms in women, while outcomes are similar in men and women in developed nations. Smoking does not play a major role in women’s recovery. Men with comorbidity of smoking and hypertension were seen to be at higher risk and age played a major role in recovery.