Ultra-deep three-dimensional optical coherence tomography in turbid media

Ultra-deep three-dimensional optical coherence tomography in turbid media | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Article Ultra-deep three-dimensional optical coherence tomography in turbid media Zhihua Ding, Lu Yang, Tao Han, Yun Tang, Changyong Chen, Cui Ma, and 1 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-4231224/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Ultra-deep three-dimensional (3D) optical coherence tomography (OCT) in turbid media is reported. Parallel detection along depth combined with scanning detection across lateral field is exploited in a swept-source OCT system to obtain the depth-resolved reflection matrices. Scanning detection enables the use of a highspeed swept source and a matched detector providing the required depth range for ultra-deep imaging. Disturbances intrinsic to scanning detection are compensated with negligible intra-frame phase variations to ensure satisfactory reconstruction by the inter-frame phase insensitive algorithm. 3D OCT imaging with an ultra-deep imaging depth of 11.5 times the scattering mean-free-path and a triple extension of the imaging depth achieved by a conventional SS-OCT is realized. The measurement time for 3D imaging (125μm×125μm×4mm ) is ~5 min, a significant leap over the time-domain matrix OCT where 6 min is taken for only one specified depth. Physical sciences/Optics and photonics/Other photonics/Biophotonics Biological sciences/Biological techniques/Imaging/Optical imaging Full Text Additional Declarations There is NO Competing Interest. Supplementary Files Supplementaryinformation.pdf Supplementary information Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-4231224","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Article","associatedPublications":[],"authors":[{"id":295041711,"identity":"4dd3a5cc-190e-4f63-bc8d-13ecd05424ee","order_by":0,"name":"Zhihua 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