Diagnostic accuracy of frozen section in ovarian masses: A single centre study.

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This study evaluated the diagnostic accuracy of intraoperative frozen sections for ovarian masses, finding 90.0% overall accuracy with high sensitivity and specificity for malignant and benign tumors, but lower sensitivity for borderline tumors.

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Abstract

BackgroundOvarian mass is not an uncommon imaging finding in women of all age groups. Hence, frozen section plays a very important role in determining the nature of the mass and, thus, deciding the appropriate surgical procedure. In the present study, we aim to analyze the accuracy of frozen sections at our center in diagnosing benign, borderline, and malignant tumors.MethodsA total data on 50 patients were collected who were operated between February 2020 and January 2022, and frozen sections were sent intraoperatively. The results were compared with the final histopathology report, and the accuracy, sensitivity, specificity, positive predictive value, and negative predictive value were analyzed for diagnosing benign, borderline, and malignant masses.ResultsThe accuracy of frozen section analysis at our center was 90.0%. The sensitivity for diagnosing malignant tumors was 89.4%, with a specificity of 100%. For benign tumors, the sensitivity and specificity were 96.2% and 86.9%, respectively. Borderline tumors had the lowest sensitivity of 50.0% with specificity of 95.6%.ConclusionIntraoperative frozen sections are a very good and necessary tool for the identification of ovarian tumors. It helps to prevent unnecessary extensive surgeries in benign tumors, especially in young patients, and complete surgery in one sitting in cases of malignancy.

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