Highly Sensitive Detection of Kojic Acid in Food Samples Using Fluorescent Carbon Dots derived from Pomegranate peel

preprint OA: closed
Full text JSON View at publisher
Full text 12,801 characters · extracted from preprint-html · click to expand
Highly Sensitive Detection of Kojic Acid in Food Samples Using Fluorescent Carbon Dots derived from Pomegranate peel | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Article Highly Sensitive Detection of Kojic Acid in Food Samples Using Fluorescent Carbon Dots derived from Pomegranate peel Omnia Omar, Ahmed Saad, Mohsen Ghali This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-4412905/v1 This work is licensed under a CC BY 4.0 License Status: Published Journal Publication published 10 Sep, 2024 Read the published version in Scientific Reports → Version 1 posted 13 You are reading this latest preprint version Abstract We report on this work development of a highly responsive optical sensor for the detection of Kojic acid (KA) using fluorescent Carbon dots (CDs) derived from pomegranate peel. The CDs were extensively characterized to validate their structural properties and intrinsic fluorescence. Utilizing the fluorescence of synthesized CDs, the optical sensor based on the CDs fluorescence quenching. Sensor was developed for the rapid and sensitive detection of KA in food products, such as vinegar and soy sauce. The sensor exhibited high performance in a wide KA concentration range of 120–1200 µM with a limit of detection LOD reached 30 µM, showcasing its potential for practical applications in assessing food quality and safety. Physical sciences/Nanoscience and technology/Graphene Physical sciences/Nanoscience and technology/Nanoscale devices Physical sciences/Nanoscience and technology/Nanoscale materials Physical sciences/Nanoscience and technology/Other nanotechnology Photoluminescence KA Optical sensors Nano-Carbon Biomass. Full Text Additional Declarations No competing interests reported. Cite Share Download PDF Status: Published Journal Publication published 10 Sep, 2024 Read the published version in Scientific Reports → Version 1 posted Editorial decision: Revision requested 05 Jun, 2024 Reviews received at journal 05 Jun, 2024 Reviewers agreed at journal 03 Jun, 2024 Reviews received at journal 03 Jun, 2024 Reviewers agreed at journal 25 May, 2024 Reviewers agreed at journal 24 May, 2024 Reviews received at journal 23 May, 2024 Reviewers agreed at journal 22 May, 2024 Reviewers invited by journal 22 May, 2024 Editor assigned by journal 22 May, 2024 Editor invited by journal 21 May, 2024 Submission checks completed at journal 20 May, 2024 First submitted to journal 13 May, 2024 You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-4412905","acceptedTermsAndConditions":true,"allowDirectSubmit":false,"archivedVersions":[],"articleType":"Article","associatedPublications":[],"authors":[{"id":307542562,"identity":"9624dfd1-384a-4198-9751-1534e306a738","order_by":0,"name":"Omnia Omar","email":"","orcid":"","institution":"Egypt-Japan University of Science and Technology","correspondingAuthor":false,"prefix":"","firstName":"Omnia","middleName":"","lastName":"Omar","suffix":""},{"id":307542563,"identity":"6c3e9709-5b76-42a4-b017-d1e5bc44892b","order_by":1,"name":"Ahmed Saad","email":"","orcid":"","institution":"Egypt-Japan University of Science and Technology","correspondingAuthor":false,"prefix":"","firstName":"Ahmed","middleName":"","lastName":"Saad","suffix":""},{"id":307542564,"identity":"e38d6bde-8565-40be-bf64-22df0b5f8874","order_by":2,"name":"Mohsen Ghali","email":"data:image/png;base64,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","orcid":"","institution":"Egypt-Japan University of Science and Technology","correspondingAuthor":true,"prefix":"","firstName":"Mohsen","middleName":"","lastName":"Ghali","suffix":""}],"badges":[],"createdAt":"2024-05-13 11:23:53","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-4412905/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-4412905/v1","draftVersion":[],"editorialEvents":[{"content":"https://doi.org/10.1038/s41598-024-70844-2","type":"published","date":"2024-09-10T15:58:02+00:00"}],"editorialNote":"","failedWorkflow":false,"files":[{"id":64619207,"identity":"fc07b2ae-e0b2-4e77-8a6a-76ac6ae421b2","added_by":"auto","created_at":"2024-09-16 16:12:41","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":1309599,"visible":true,"origin":"","legend":"","description":"","filename":"HighlySensitiveDetectionofKojicAcidinFoodSamplesUsingFluorescentCarbonDotsderivedfromPomegranatepeel.pdf","url":"https://assets-eu.researchsquare.com/files/rs-4412905/v1_covered_fe2687aa-c6a0-44a9-926f-372be1284721.pdf"}],"financialInterests":"No competing interests reported.","formattedTitle":"Highly Sensitive Detection of Kojic Acid in Food Samples Using Fluorescent Carbon Dots derived from Pomegranate peel","fulltext":[],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":false,"highlight":"","institution":"","isAcceptedByJournal":true,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":true,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"scientific-reports","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"scirep","sideBox":"Learn more about [Scientific Reports](http://www.nature.com/srep/)","snPcode":"","submissionUrl":"","title":"Scientific Reports","twitterHandle":"","acdcEnabled":true,"dfaEnabled":true,"editorialSystem":"stoa","reportingPortfolio":"Scientific Reports","inReviewEnabled":true,"inReviewRevisionsEnabled":true},"keywords":"Photoluminescence, KA, Optical sensors, Nano-Carbon, Biomass.","lastPublishedDoi":"10.21203/rs.3.rs-4412905/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-4412905/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003eWe report on this work development of a highly responsive optical sensor for the detection of Kojic acid (KA) using fluorescent Carbon dots (CDs) derived from pomegranate peel. The CDs were extensively characterized to validate their structural properties and intrinsic fluorescence. Utilizing the fluorescence of synthesized CDs, the optical sensor based on the CDs fluorescence quenching. Sensor was developed for the rapid and sensitive detection of KA in food products, such as vinegar and soy sauce. The sensor exhibited high performance in a wide KA concentration range of 120\u0026ndash;1200 \u0026micro;M with a limit of detection LOD reached 30 \u0026micro;M, showcasing its potential for practical applications in assessing food quality and safety.\u003c/p\u003e","manuscriptTitle":"Highly Sensitive Detection of Kojic Acid in Food Samples Using Fluorescent Carbon Dots derived from Pomegranate peel","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2024-05-30 10:32:28","doi":"10.21203/rs.3.rs-4412905/v1","editorialEvents":[{"type":"communityComments","content":0},{"type":"decision","content":"Revision requested","date":"2024-06-05T12:25:38+00:00","index":"","fulltext":""},{"type":"editorInvitedReview","content":"","date":"2024-06-05T04:19:23+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"267939737691192852853614912221425884310","date":"2024-06-03T18:30:28+00:00","index":"hide","fulltext":""},{"type":"editorInvitedReview","content":"","date":"2024-06-03T16:15:17+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"71456952048652149123773297849798736645","date":"2024-05-26T01:56:06+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"150208328289054394453845484423747542371","date":"2024-05-24T09:11:55+00:00","index":"hide","fulltext":""},{"type":"editorInvitedReview","content":"","date":"2024-05-23T04:40:14+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"289500554561609047140785036189205904044","date":"2024-05-22T06:44:24+00:00","index":"hide","fulltext":""},{"type":"reviewersInvited","content":"","date":"2024-05-22T06:41:20+00:00","index":"","fulltext":""},{"type":"editorAssigned","content":"","date":"2024-05-22T06:21:56+00:00","index":"","fulltext":""},{"type":"editorInvited","content":"","date":"2024-05-21T08:05:38+00:00","index":"","fulltext":""},{"type":"checksComplete","content":"","date":"2024-05-20T07:29:06+00:00","index":"","fulltext":""},{"type":"submitted","content":"Scientific Reports","date":"2024-05-13T11:22:37+00:00","index":"","fulltext":""}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"scientific-reports","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"scirep","sideBox":"Learn more about [Scientific Reports](http://www.nature.com/srep/)","snPcode":"","submissionUrl":"","title":"Scientific Reports","twitterHandle":"","acdcEnabled":true,"dfaEnabled":true,"editorialSystem":"stoa","reportingPortfolio":"Scientific Reports","inReviewEnabled":true,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"2ed16e4d-a1f6-4f1e-9c3d-e0a53b650fcb","owner":[],"postedDate":"May 30th, 2024","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"published-in-journal","subjectAreas":[{"id":32480786,"name":"Physical sciences/Nanoscience and technology/Graphene"},{"id":32480787,"name":"Physical sciences/Nanoscience and technology/Nanoscale devices"},{"id":32480788,"name":"Physical sciences/Nanoscience and technology/Nanoscale materials"},{"id":32480789,"name":"Physical sciences/Nanoscience and technology/Other nanotechnology"}],"tags":[],"updatedAt":"2024-09-16T16:04:12+00:00","versionOfRecord":{"articleIdentity":"rs-4412905","link":"https://doi.org/10.1038/s41598-024-70844-2","journal":{"identity":"scientific-reports","isVorOnly":false,"title":"Scientific Reports"},"publishedOn":"2024-09-10 15:58:02","publishedOnDateReadable":"September 10th, 2024"},"versionCreatedAt":"2024-05-30 10:32:28","video":"","vorDoi":"10.1038/s41598-024-70844-2","vorDoiUrl":"https://doi.org/10.1038/s41598-024-70844-2","workflowStages":[]},"version":"v1","identity":"rs-4412905","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-4412905","identity":"rs-4412905","version":["v1"]},"buildId":"qtupq5eGEP_6zYnWcrvyt","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

Ask this paper AI returns verbatim quotes from the full text · source: preprint-html

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Citation neighborhood (no data yet)

We don't have any in-corpus citations linked to this paper yet. This is a recent paper (2024) — citers typically take a year or two to land, and the OpenAlex reference graph may still be filling in.

Source provenance

europepmc
last seen: 2026-05-20T01:45:00.602351+00:00